Abstract: A joining connection with a weld seam running between a first metal component and a second metal component and produced by a beam welding method. The weld seam has a weld seam main section extending along a joining gap formed between the metal components, the weld seam has a weld seam starting section leading from the direction of the joining gap into the first or second component. The first or second component has a recess in the region of the weld seam starting section that is lowered in relation to the upper edges of the two components forming the joining gap, and/or the weld seam has a weld seam end section leading from the direction of the joining gap into the first or second component.

Abstract: Combustion gas of an internal combustion engine passes through an exhaust system to an outlet opening. A detection device generates a state signal that describes an engine noise of the internal combustion engine. A control apparatus actuates at least one loudspeaker to produce a sound at the outlet opening based on the state signal to compensate for the engine noise or produce another engine noise, independently of the state signal based on predetermined audio data and thereby to use the at least one loudspeaker to audibly output an advisory signal described by the audio data.

Abstract: Combustion gas of an internal combustion engine passes through an exhaust system to an outlet opening. A detection device generates a state signal that describes an engine noise of the internal combustion engine. A control apparatus actuates at least one loudspeaker to produce a sound at the outlet opening based on the state signal to compensate for the engine noise or produce another engine noise, independently of the state signal based on predetermined audio data and thereby to use the at least one loudspeaker to audibly output an advisory signal described by the audio data.

Abstract: A joining connection with a weld seam running between a first metal component and a second metal component and produced by a beam welding method. The weld seam has a weld seam main section extending along a joining gap formed between the metal components, the weld seam has a weld seam starting section leading from the direction of the joining gap into the first or second component. The first or second component has a recess in the region of the weld seam starting section that is lowered in relation to the upper edges of the two components forming the joining gap, and/or the weld seam has a weld seam end section leading from the direction of the joining gap into the first or second component.

Abstract: The invention provides a method of treating congenital muscular dystrophy due to a mutation in the LAMA2 gene in a mammal. The method comprises administering to the mammal a therapeutically effective amount of a protein comprising at least one binding domain for a laminin, at least one binding domain for ?-dystroglycan, and at least one follastatin-like domain.