Abstract: The present invention relates to a solid pharmaceutical preparation of of 8-(1,3-Dimethyl-1 H-pyrazol-4-yl)-1-(Sa)-(3-fluoro-5-methoxy-pyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one, as well as a method of making same, as well as medical uses thereof.

Abstract: The present invention relates to a solid pharmaceutical preparation of 3-(1-{3-[5-(1-Methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile, a method of making same, and medical uses thereof.

Abstract: The invention relates to a trigger shifter with virtually no takeup distance during the takeup process. In its original position, the takeup pawl is located in the immediate vicinity of the transport tooth set, such that the takeup pawl and takeup lever do not need to cover a takeup distance. In the release process, the takeup pawl, which is in the ready position to engage, is moved out of the region of the transport tooth set by means of a connecting link, preferably a shackle spring, and subsequently the retaining pawl is disengaged so that so that the cable coil can be rotated by the prestressed cable pull without any obstacles. In addition to its function of controlling the takeup pawl, the shackle spring can also provide initial tension in the retaining direction to the sliding element with the retaining pawl.