Patents by Inventor Markus Ringner

Markus Ringner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140221234
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Application
    Filed: December 30, 2013
    Publication date: August 7, 2014
    Applicant: Government of the United States Represented by the Secretary, Department of Health and Human Service
    Inventors: Javed Khan, Markus Ringner, Carsten Peterson, Paul Meltzer
  • Patent number: 8620592
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: December 31, 2013
    Assignee: The United States of America Represented by the Secretary, Department of Health and Human Services
    Inventors: Javed Khan, Markus Ringner, Carsten Peterson, Paul Meltzer
  • Patent number: 8263759
    Abstract: A method of diagnosing a disease that includes obtaining experimental data on gene selections. The gene selection functions to characterize a cancer when the expression of that gene selection is compared to the identical selection from a noncancerous cell or a different type of cancer cell. The invention also includes a method of targeting at least one product of a gene that includes administration of a therapeutic agent. The invention also includes the use of a gene selection for diagnosing a cancer.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: September 11, 2012
    Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: Javed Khan, Markus Ringner, Carsten Peterson, Paul Meltzer
  • Publication number: 20120046878
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Application
    Filed: October 31, 2011
    Publication date: February 23, 2012
    Applicants: SERVICES
    Inventors: JAVED KHAN, MARKUS RINGNÉR, CARSTEN PETERSON, PAUL MELTZER
  • Patent number: 8065092
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: November 22, 2011
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Javed Khan, Markus Ringnér, Carsten Peterson, Paul Meltzer
  • Publication number: 20100312486
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Application
    Filed: August 18, 2010
    Publication date: December 9, 2010
    Applicant: Government of the USA represented by the Secretary Dept. of Health and Human Services
    Inventors: Javed Khan, Markus Ringnér, Carsten Peterson, Paul Meltzer
  • Patent number: 7783431
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: August 24, 2010
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Javed Khan, Markus Ringner, Carsten Peterson, Paul Meltzer
  • Patent number: 7774143
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: August 10, 2010
    Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
    Inventors: Javed Khan, Markus Ringnér, Carsten Peterson, Paul Meltzer
  • Patent number: 7655397
    Abstract: A method of diagnosing a disease that includes obtaining experimental data on gene selections. The gene selection functions to characterize a cancer when the expression of that gene selection is compared to the identical selection from a noncancerous cell or a different type of cancer cell. The invention also includes a method of targeting at least one product of a gene that includes administration of a therapeutic agent. The invention also includes the use of a gene selection for diagnosing a cancer.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: February 2, 2010
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Javed Khan, Markus Ringnér, Carsten Peterson, Paul Meltzer
  • Publication number: 20090035766
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Application
    Filed: October 30, 2007
    Publication date: February 5, 2009
    Applicants: SERVICES
    Inventors: Javed Khan, Markus Ringner, Carsten Peterson, Paul Meltzer
  • Publication number: 20080181896
    Abstract: A method of diagnosing a disease that includes obtaining experimental data on gene selections. The gene selection functions to characterize a cancer when the expression of that gene selection is compared to the identical selection from a noncancerous cell or a different type of cancer cell. The invention also includes a method of targeting at least one product of a gene that includes administration of a therapeutic agent. The invention also includes the use of a gene selection for diagnosing a cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 31, 2008
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Javed Khan, Markus Ringner, Carsten Peterson, Paul Meltzer
  • Patent number: 6859736
    Abstract: This invention provides a method for protein structure alignment. More particularly, the present invention provides a method for identification, classification and prediction of protein structures. The present invention involves two key ingredients. First, an energy or cost function formulation of the problem simultaneously in terms of binary (Potts) assignment variables and real-valued atomic coordinates. Second, a minimization of the energy or cost function by an iterative method, where in each iteration (1) a mean field method is employed for the assignment variables and (2) exact rotation and/or translation of atomic coordinates is performed, weighted with the corresponding assignment variables.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: February 22, 2005
    Assignee: The Board of Trustees of the Lealand Stanford Junior University
    Inventors: Richard Blankenbecler, Mattias Ohlsson, Carsten Peterson, Markus Ringner
  • Publication number: 20040009154
    Abstract: A method of diagnosing a disease that includes obtaining experimental data on gene selections. The gene selection functions to characterize a cancer when the expression of that gene selection is compared to the identical selection from a noncancerous cell or a different type of cancer cell. The invention also includes a method of targeting at least one product of a gene that includes administration of a therapeutic agent. The invention also includes the use of a gene selection for diagnosing a cancer.
    Type: Application
    Filed: May 31, 2002
    Publication date: January 15, 2004
    Inventors: Javed Khan, Markus Ringner, Carsten Peterson, Paul Meltzer
  • Publication number: 20030207278
    Abstract: A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition.
    Type: Application
    Filed: April 25, 2002
    Publication date: November 6, 2003
    Inventors: Javed Khan, Markus Ringner, Carsten Peterson, Paul Meltzer
  • Publication number: 20020111781
    Abstract: This invention provides a method for protein structure alignment. More particularly, the present invention provides a method for identification, classification and prediction of protein structures. The present invention involves two key ingredients. First, an energy or cost function formulation of the problem simultaneously in terms of binary (Potts) assignment variables and real-valued atomic coordinates. Second, a minimization of the energy or cost function by an iterative method, where in each iteration (1) a mean field method is employed for the assignment variables and (2) exact rotation and/or translation of atomic coordinates is performed, weighted with the corresponding assignment variables.
    Type: Application
    Filed: April 2, 2001
    Publication date: August 15, 2002
    Inventors: Richard Blankenbecler, Mattias Ohlsson, Carsten Peterson, Markus Ringner