Patents by Inventor Markus Roessler

Markus Roessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200141930
    Abstract: The present invention relates to a method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Schraeml, Markus Roessler, Michael Gerg
  • Patent number: 10564151
    Abstract: The present invention relates to a method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: February 18, 2020
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Michael Schraeml, Markus Roessler, Michael Gerg
  • Patent number: 10175241
    Abstract: The present invention relates to the assessment of lung cancer. It discloses the use of protein ASC in the assessment of lung cancer. It also relates to a method for assessing lung cancer in vitro using a liquid sample, derived from an individual by measuring ASC in the sample. Measurement of ASC can, e.g., be used in the early detection or in the follow-up of patients with lung cancer.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: January 8, 2019
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Herbert Andres, Marie-Luise Hagmann, Johann Karl, Markus Roessler, Michael Tacke
  • Publication number: 20160377625
    Abstract: Disclosed is a method aiding in the assessment of cancer. More specifically disclosed is the use of the arginine-rich metastasized in early tumors protein (=ARMET) as a universal marker of different cancer types. ARMET aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are, e.g., breast, ovary, cervix, head and neck, endometrium, melanoma, bladder, kidney, pancreas, prostate, esophagus, stomach or bile duct cancer. Further disclosed is a method for assessing cancer from a liquid sample, derived from an individual by measuring ARMET in the sample. Measurement of ARMET can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
    Type: Application
    Filed: September 8, 2016
    Publication date: December 29, 2016
    Inventors: Markus Roessler, Johann Karl, Julia Riedlinger, Ingo Lindner, Michael Tacke
  • Patent number: 9518990
    Abstract: Disclosed is a method aiding in the assessment of cancer. It involves the use of the secernin-1 protein (SCRN1) as a universal marker of different cancer types. More specifically disclosed is a method for assessing cancer from a liquid sample derived from an individual by measuring SCRN1 in the sample. Measurement of SCRN1 can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: December 13, 2016
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Norbert Wild, Marie-Luise Hagmann, Johann Karl, Julia Riedlinger, Markus Roessler, Michael Tacke
  • Publication number: 20160252500
    Abstract: The present invention relates to a method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto.
    Type: Application
    Filed: May 4, 2016
    Publication date: September 1, 2016
    Inventors: Michael Schraeml, Markus Roessler, Michael Gerg
  • Publication number: 20160169895
    Abstract: Methods aiding in the assessment of cancer comprising use of the Flap endonuclease-1 protein (=FEN1) as a universal marker of different cancer types are provided. In particular, methods for assessing cancer from a liquid sample derived from an individual, which comprise measuring FEN1 in the sample are disclosed. Measurement of FEN1 is useful for the early detection of cancer or in the monitoring of patients who undergo surgery for tumor removal.
    Type: Application
    Filed: February 18, 2016
    Publication date: June 16, 2016
    Inventors: Norbert Wild, Marie-Luise Hagmann, Johann Karl, Julia Riedlinger, Markus Roessler, Michael Tacke
  • Patent number: 8980573
    Abstract: The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the human fibroblast activation protein (FAP/seprase) as a universal marker of different cancer types. Seprase aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are, e.g., esophagus, head and neck cancer, stomach cancer, bile duct cancer, pancreas cancer, kidney cancer, cervix cancer, ovary cancer, breast cancer, bladder cancer, endometrium cancer or prostate cancer. Furthermore, it especially relates to a method for assessing cancer from a liquid sample, derived from an individual by measuring seprase in said sample. Measurement of seprase can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: March 17, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Wolfgang Rollinger, Johann Karl, Jarema Peter Kochan, Markus Roessler, Michael Tacke
  • Publication number: 20150072355
    Abstract: Methods aiding in the assessment of cancer comprising use of the Flap endonuclease-1 protein (=FEN1) as a universal marker of different cancer types are provided. In particular, methods for assessing cancer from a liquid sample derived from an individual, which comprise measuring FEN1 in the sample are disclosed. Measurement of FEN1 is useful for the early detection of cancer or in the monitoring of patients who undergo surgery for tumor removal.
    Type: Application
    Filed: October 31, 2014
    Publication date: March 12, 2015
    Inventors: Norbert Wild, Marie-Luise Hagmann, Johann Karl, Julia Riedlinger, Markus Roessler, Michael Tacke
  • Publication number: 20150056642
    Abstract: An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein ARMET in said sample in vitro.
    Type: Application
    Filed: November 5, 2014
    Publication date: February 26, 2015
    Inventors: Johann Karl, Julia Riedlinger, Markus Roessler
  • Patent number: 8951738
    Abstract: The present invention relates to the assessment of lung cancer. It discloses the use of protein CYBP in the assessment of lung cancer. It also relates to a method for assessing lung cancer in vitro using a liquid sample, derived from an individual by measuring CYBP in said sample. Measurement of CYBP can, e.g., be used in the early detection or in the follow-up of patients with lung cancer.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: February 10, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Herbert Andres, Johann Karl, Julia Riedlinger, Markus Roessler, Michael Tacke, Michael Thierolf
  • Publication number: 20140219998
    Abstract: Disclosed is a method aiding in the assessment of cancer. More specifically disclosed is the use of the arginine-rich metastasized in early tumors protein (=ARMET) as a universal marker of different cancer types. ARMET aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are, e.g., breast, ovary, cervix, head and neck, endometrium, melanoma, bladder, kidney, pancreas, prostate, esophagus, stomach or bile duct cancer. Further disclosed is a method for assessing cancer from a liquid sample, derived from an individual by measuring ARMET in the sample. Measurement of ARMET can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
    Type: Application
    Filed: April 14, 2014
    Publication date: August 7, 2014
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Markus Roessler, Johann Karl, Julia Riedlinger, Ingo Lindner, Michael Tacke
  • Patent number: 8741587
    Abstract: Disclosed is a method aiding in the assessment of cancer. More specifically disclosed is the use of the arginine-rich metastasized in early tumors protein (=ARMET) as a universal marker of different cancer types. ARMET aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are, e.g., breast, ovary, cervix, head and neck, endometrium, melanoma, bladder, kidney, pancreas, prostate, esophagus, stomach or bile duct cancer. Further disclosed is a method for assessing cancer from a liquid sample, derived from an individual by measuring ARMET in the sample. Measurement of ARMET can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: June 3, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Markus Roessler, Johann Karl, Julia Riedlinger, Ingo Lindner, Michael Tacke
  • Publication number: 20130344516
    Abstract: An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein ARMET in said sample in vitro.
    Type: Application
    Filed: September 10, 2013
    Publication date: December 26, 2013
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Johann Karl, Julia Riedlinger, Markus Roessler
  • Patent number: 8252542
    Abstract: Disclosed is a method aiding in the assessment of squamous cell carcinoma (SCC). It involves the use of the protein serpin B13 as a marker of SCC. Furthermore, the disclosure relates to a method for assessing lung cancer in a tissue sample derived from a patient having non-small cell lung carcinoma (NSCLC) and for differentiating SCC from adenocarcinoma or large cell carcinoma of the lung.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: August 28, 2012
    Assignee: Roche Diagnostics Operations Inc.
    Inventors: Markus Roessler, Liliana Mantovani-Endl, Michael Tacke
  • Publication number: 20120196303
    Abstract: The present invention relates to the assessment of lung cancer. It discloses the use of protein CYBP in the assessment of lung cancer. It also relates to a method for assessing lung cancer in vitro using a liquid sample, derived from an individual by measuring CYBP in said sample. Measurement of CYBP can, e.g., be used in the early detection or in the follow-up of patients with lung cancer.
    Type: Application
    Filed: October 11, 2011
    Publication date: August 2, 2012
    Inventors: Herbert Andres, Johann Karl, Julia Riedlinger, Markus Roessler, Michael Tacke, Michael Thierolf
  • Publication number: 20120157335
    Abstract: Methods aiding in the assessment of cancer comprising use of the Flap endonuclease-1 protein (=FEN1) as a universal marker of different cancer types are provided. In particular, methods for assessing cancer from a liquid sample derived from an individual, which comprise measuring FEN1 in the sample are disclosed. Measurement of FEN1 is useful for the early detection of cancer or in the monitoring of patients who undergo surgery for tumor removal.
    Type: Application
    Filed: January 17, 2012
    Publication date: June 21, 2012
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Norbert Wild, Marie-Luise Hagmann, Johann Karl, Julia Riedlinger, Markus Roessler, Michael Tacke
  • Publication number: 20120028835
    Abstract: Disclosed is a method aiding in the assessment of cancer. It involves the use of the secernin-1 protein (SCRN1) as a universal marker of different cancer types. More specifically disclosed is a method for assessing cancer from a liquid sample derived from an individual by measuring SCRN1 in the sample. Measurement of SCRN1 can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
    Type: Application
    Filed: October 13, 2011
    Publication date: February 2, 2012
    Inventors: Norbert Wild, Marie-Luise Hagmann, Johann Karl, Julia Kloeckner, Markus Roessler, Michael Tacke
  • Publication number: 20110275100
    Abstract: Disclosed is a method aiding in the assessment of squamous cell carcinoma (SCC). It involves the use of the protein serpin B13 as a marker of SCC. Furthermore, the disclosure relates to a method for assessing lung cancer in a tissue sample derived from a patient having non-small cell lung carcinoma (NSCLC) and for differentiating SCC from adenocarcinoma or large cell carcinoma of the lung.
    Type: Application
    Filed: July 20, 2011
    Publication date: November 10, 2011
    Inventors: Markus Roessler, Liliana Mantovani-Endl, Michael Tacke
  • Publication number: 20110212464
    Abstract: The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the proapoptotic caspase adaptor protein (=PACAP) as a universal marker of different types of cancer. PACAP aids in the assessment of pulmonary or lung cancer (LC), particularly of non-small cell lung carcinoma (NSCLC), but also of other specific types of cancer. Such specific types of cancer are e.g. colon, bladder, cervix, ovary, endometrial, head and neck, breast, melanoma, pancreas, kidney, prostate, esophagus, stomach or bile duct cancer. Furthermore, the present invention especially relates to a method for assessing cancer from a liquid sample, derived from an individual by measuring PACAP in said sample. Measurement of PACAP can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
    Type: Application
    Filed: May 3, 2011
    Publication date: September 1, 2011
    Inventors: Marie-Luise Hagmann, Johann Karl, Julia Kloeckner, Markus Roessler, Michael Tacke