Abstract: The present teachings relate to a method for monitoring and/or controlling a production process for manufacturing at least one industrial product at an industrial plant comprising at least one equipment by processing at least one input, the method comprising: receiving, via an input inter-face, real-time process data from the equipment; determining, via the computing unit, a subset of the real-time process data; providing as output data the subset of the real-time process data. The present teachings also relate to a system, a use, and a software product.

Abstract: The present teachings relate to a method for controlling a production process, for manufacturing a chemical product, comprising: providing an upstream object identifier comprising input material data and at least one desired performance parameter related to the chemical product; determining a set of process and/or operation parameters based on the upstream object identifier and the at least one desired performance parameter; determining zone-specific control settings for each of the equipment zones based on the determined set of process and/or operation parameters and historical data; providing the zone-specific control settings for controlling the production of the chemical product related to the upstream object identifier. The present teachings also relate to a system for controlling a production process, a use of the control settings, and a software product for implementing the method steps disclosed herein.

Abstract: The present teachings relate to a method for digitally tracking a chemical product manufactured at an industrial plant comprising at least one equipment; and, the product being manufactured by processing, via the equipment, at least one input material using a production process, which method comprises: providing, via an interface, an object identifier comprising input material data; wherein the input material data is indicative of one or more property of the input material, receiving, via the interface, process data from the equipment; the process data being indicative of the process parameters and/or equipment operating conditions that the input material is processed under, appending, to the object identifier, at least a part of the process data. The present teachings also relate to a system for digitally tracking a chemical product and a software product.

Abstract: The present teachings relate to a method for controlling a downstream production process for manufacturing a chemical product using at least one precursor material, the method comprising: providing a set of downstream control settings for controlling the production of the chemical product, wherein the downstream control settings are determined based on: a downstream object identifier; the downstream object identifier comprising precursor data; at least one desired downstream performance parameter related to the chemical product; downstream historical data; and wherein the set of downstream control settings is usable for manufacturing the chemical product at the downstream industrial plant. The present teachings also relate to a system, a use and a software product.

Abstract: The invention provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein A and R1-R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, A, X, m and n are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein RA, RB, RC, RC1 and W are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: Compounds of formula (I) wherein R1, R2, A, W, m, n, p and q are as described herein, compositions including the compounds and methods of using the compounds as autotaxin inhibitors.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, X, W, m and n are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, A, X and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, Y and R2 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, A, X, m and n are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R9, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, A, X, m and n are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R8, X, A and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10 and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, Y and R2 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein RA, RB, RC, RC1 and W are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R9, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.