Abstract: Methods for controlling a perfusion bioprocess are described, the method comprising: controlling the value of one or more controlled variables selected from the number or density of viable cells in the bioreactor, the volume of culture in the bioreactor, and the concentration of one or more metabolites in the bioreactor using one or more control loops each configured to control a non-overlapping subset of the controlled variables by setting the value of one or more manipulated variables selected from the feed flow rate, the bleed flow rate and the permeate flow rate, wherein at least one of the control loops uses a controller that identifies a value of the one or more manipulated variables that optimises a control objective using a prediction of the value of the subset of controlled variables from a dynamic model of the bioprocess describing the rate of change of the one or more controlled variables.

Abstract: An adjusting apparatus for a comfort element swingable in relation to a support structure, in particular for an armrest of a vehicle, includes a latching device actuatable by adjusting the comfort element and having a latching arm connected to the comfort element and a latching lever interacting with the latching arm. A swing position of the comfort element is locked by providing a locking lever which is swingably articulated to the latching arm and has an engagement portion which locks the swing position by a spring force, when the engagement portion assumes an engagement position with a locking portion of a locking element that is fixed to the support structure, and the swing position of the comfort element is unlocked by an actuator by which the locking lever is disengageable from the engagement position with the locking element.

Abstract: An adjusting apparatus for a comfort element swingable in relation to a support structure, in particular for an armrest of a vehicle, includes a latching device actuatable by adjusting the comfort element and having a latching arm connected to the comfort element and a latching lever interacting with the latching arm. A swing position of the comfort element is locked by providing a locking lever which is swingably articulated to the latching arm and has an engagement portion which locks the swing position by a spring force, when the engagement portion assumes an engagement position with a locking portion of a locking element that is fixed to the support structure, and the swing position of the comfort element is unlocked by an actuator by which the locking lever is disengageable from the engagement position with the locking element.