Patents by Inventor Markus SPELBERG

Markus SPELBERG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPASE WITH IMPROVED STEREOSELECTIVITY AND LIPASE-BASED CHIRAL RESOLUTION METHODS
    Publication number: 20260258381
    Abstract: The present invention relates to proteins having improved lipase activity, nucleic acid molecules encoding respective proteins having improved lipase activity and methods for chiral resolution of secondary alcohols.
    Type: Application
    Filed: March 7, 2024
    Publication date: September 3, 2026
    Inventors: Elia Calderini, Alba Hernandez Martin, Oliver Kensch, Florian Richter, Christian Pitzler, Wahed Ahmed Moradi, Andreas Rembiak, Mark James Ford, Anton Lishchynskyi, Markus Spelberg, Nadine Zumbrägel, Fabian Basso, Florian Erver
  • Method for the preparation of chiral alpha haloalkanoic acids
    Patent number: 11053518
    Abstract: What is described herein relates to a method of selectively hydrolyzing an enantiomer of an alpha haloalkanoic acid according to formula I employing a polypeptide having dehalogenase activity comprising an amino acid sequence as set forth in SEQ ID NO. 1 or SEQ ID NO. 4 or a sequence with at least 80% sequence identity to either of said sequences and to the use of said method.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: July 6, 2021
    Assignee: Bayer Aktiengesellschaft
    Inventors: Markus Spelberg, Julian Egger
  • ENANTIONSELECTIVE ENZYMATIC SULFOXIDATION OF CHIRAL ARYLSULFIDES
    Publication number: 20200370080
    Abstract: What is described herein refers to isolated nucleic acid fragments encoding an oxygenase subunit (StyA) and a reductase subunit (StyB), wherein the polypeptide encoded for by the nucleotide sequence for the oxygenase subunit (StyA) and the nucleotide sequence for the reductase subunit (StyB) have activity towards chiral arylsulfides.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 26, 2020
    Inventors: Rainhard KOCH, Simon KLAFFL, Markus SPELBERG, Dirk TISCHLER, Michael SCHLOEMANN, Anika SCHOLTISSEK, Thomas HEINE, Bruno BUEHLER, Andreas SCHMID, Christian WILLRODT
  • METHOD FOR THE PREPARATION OF CHIRAL ALPHA HALOALKANOIC ACIDS
    Publication number: 20200277633
    Abstract: What is described herein relates to a method of selectively hydrolyzing an enantiomer of an alpha haloalkanoic acid according to formula I employing a polypeptide having dehalogenase activity comprising an amino acid sequence as set forth in SEQ ID NO. 1 or SEQ ID NO. 4 or a sequence with at least 80% sequence identity to either of said sequences and to the use of said method.
    Type: Application
    Filed: September 24, 2018
    Publication date: September 3, 2020
    Inventors: Markus SPELBERG, Julian EGGER