Patents by Inventor Markus Stein
Markus Stein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150027254Abstract: A motor vehicle drive train device includes a multi-group transmission with a main group providing at least one forward transmission gear and at least one reverse transmission gear, and a downstream group downstream from the main group. The device also includes a control and/or regulation unit having a gear change function for shifting the main group at least in one transmission gear change operation in order to engage a transmission gear opposite to the current direction of travel. The control and/or regulation unit has a synchronization function which is provided for shifting the downstream group in order to engage the transmission gear opposite to the current direction of travel.Type: ApplicationFiled: February 1, 2013Publication date: January 29, 2015Applicant: Daimler AGInventors: Manfred Guggolz, Juergen Hertlein, Werner Hillenbrand, Steffen Keppeler, Markus Stein, David Ulmer
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Patent number: 8561455Abstract: A sensor head for measurement of a film, includes a guide surface (14) for the film, at least one sensor element (28, 30) integrated in the guide surface for measuring a property of the film, and a generator for generating an air cushion between the guide surface (14) and the film, the generator including a system for supplying a pressure medium, and a guide member (12) that is made of a porous material and forms at least a part of the guide surface (14) and is adapted to distributedly discharge the pressure medium into the air cushion, the guide member (12) having a channel system (16, 18) that divides the guide surface (14) into a plurality of fields (20, 22) that, if not disconnected, are connected only by narrow lands, the channel system being configured for draining the pressure medium from the air cushion.Type: GrantFiled: November 3, 2010Date of Patent: October 22, 2013Assignee: Plast-Control GmbHInventors: Stefan Konermann, Markus Stein
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Patent number: 8561313Abstract: An apparatus for measuring film bubbles (10), includes a guide track (22) that extends in a circumferential direction of the film bubble with a constant spacing relative to the latter, the guide track guiding a carriage (20) which carries a measuring head (12) facing the peripheral surface of the film bubble (10), the measuring head (12) is connected to a free end of a cantilever (18) via an articulated joint (16), the cantilever having another end pivotally connected to the carriage (20), and a compensating drive mechanism (30) for correcting a change in the orientation of the measuring head (12) resulting from a pivotal movement of the cantilever (18) is associated with the articulated joint (16).Type: GrantFiled: April 27, 2011Date of Patent: October 22, 2013Assignee: Plast-Control GmbHInventors: Frank Müller, Markus Stein, Stefan Konermann
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Patent number: 8315833Abstract: A method for contactless capacitive thickness measurement of a flat material (10) that is placed in the fringe field (32) of a capacitor (C1,C2), with simultaneous measurement of the width L of an air gap (16) between the flat material and the capacitor plates, in which the capacities gL, kL of two capacitors (C1, C2) are measured whose fringe fields (32) decay at different rates towards the flat material (10), and in that both, the thickness D of the flat material (10) and the width L of the air gap (16) are determined on the basis of the condition that, for each capacitor (C1, C2), the measured capacity gL, kL is equal to the integral of the capacity gradient g?, k? over the thickness of the flat material (10).Type: GrantFiled: August 19, 2008Date of Patent: November 20, 2012Assignee: Plast-Control GmbHInventors: Stefan Konermann, Markus Stein
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Publication number: 20110265556Abstract: An apparatus for measuring film bubbles (10), includes a guide track (22) that extends in a circumferential direction of the film bubble with a constant spacing relative to the latter, the guide track guiding a carriage (20) which carries a measuring head (12) facing the peripheral surface of the film bubble (10), the measuring head (12) is connected to a free end of a cantilever (18) via an articulated joint (16), the cantilever having another end pivotally connected to the carriage (20), and a compensating drive mechanism (30) for correcting a change in the orientation of the measuring head (12) resulting from a pivotal movement of the cantilever (18) is associated with the articulated joint (16).Type: ApplicationFiled: April 27, 2011Publication date: November 3, 2011Applicant: PLAST-CONTROL GMBHInventors: Frank Müller, Markus Stein, Stefan Konermann
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Patent number: 8021861Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.Type: GrantFiled: March 29, 2007Date of Patent: September 20, 2011Assignee: University of British ColumbiaInventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai
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Publication number: 20110107818Abstract: A sensor head for measurement of a film, includes a guide surface (14) for the film, at least one sensor element (28, 30) integrated in the guide surface for measuring a property of the film, and a generator for generating an air cushion between the guide surface (14) and the film, the generator including a system for supplying a pressure medium, and a guide member (12) that is made of a porous material and forms at least a part of the guide surface (14) and is adapted to distributedly discharge the pressure medium into the air cushion, the guide member (12) having a channel system (16, 18) that divides the guide surface (14) into a plurality of fields (20, 22) that, if not disconnected, are connected only by narrow lands, the channel system being configured for draining the pressure medium from the air cushion.Type: ApplicationFiled: November 3, 2010Publication date: May 12, 2011Applicant: PLAST-CONTROL GMBHInventors: Stefan Konermann, Markus Stein
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Publication number: 20110003339Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.Type: ApplicationFiled: March 29, 2007Publication date: January 6, 2011Applicant: The University of British ColumbiaInventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai
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Publication number: 20100256951Abstract: A method for contactless capacitive thickness measurement of a flat material (10) that is placed in the fringe field (32) of a capacitor (C1, C2), with simultaneous measurement of the width L of an air gap (16) between the flat material and the capacitor plates, in which the capacities gL, kL of two capacitors (C1, C2) are measured whose fringe fields (32) decay at different rates towards the flat material (10), and in that both, the thickness D of the flat material (10) and the width L of the air gap (16) are determined on the basis of the condition that, for each capacitor (C1, C2), the measured capacity gL, kL is equal to the integral of the capacity gradient g?, k? over the thickness of the flat material (10).Type: ApplicationFiled: August 19, 2008Publication date: October 7, 2010Applicant: PLAST-CONTROL GMBHInventors: Stefan Konermann, Markus Stein
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Patent number: 7759462Abstract: A polypeptide, called Tir (for translocated intimin receptor, which is secreted by attaching and effacing pathogens, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli. These bacterial pathogens inserts their own receptors into mammalian cell surfaces, to which the bacterial pathogen then adheres to trigger additional host signaling events and actin nucleation. Diagnosis of disease caused by pathogenic E. coli can be performed by the use of antibodies which bind to Tir to detect the protein or the use of nucleic acid probes for detection of nucleic acids encoding Tir polypeptide. Isolated nucleic acid sequences encoding Tir polypeptide, Tir peptides, a recombinant method for producing recombinant Tir, antibodies which bind to Tir, and a kit for the detection of Tir-producing E. coli are provided. A method of immunizing a host with Tir to induce a protective immune response to Tir or a second polypeptide of interst is also provided.Type: GrantFiled: November 9, 2006Date of Patent: July 20, 2010Assignee: University of British ColumbiaInventors: Brett B. Finlay, Brendan Kenny, Rebekah DeVinney, Markus Stein
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Publication number: 20090299930Abstract: A method of measuring the thickness profile of a film produced in a blow film line having a rotatable pull-off rig in which a flattened film tube is scanned by performing individual measurements at measurement positions distributed over the width over the film tube and, in each individual measurement, the total thickness of two segments of the film tube is measured that are superposed at the measurement position, the thickness profile is calculated from the measured values obtained for a number individual measurements that is larger than the number of measurement positions, the improvement including the steps of training a neural network with measured values for the total thicknesses, which measured values have been obtained in simulated or real measurement processes with known thickness profiles and supplying the measured results obtained by scanning the film tube to the neural network for calculating the thickness profile.Type: ApplicationFiled: May 26, 2009Publication date: December 3, 2009Applicant: PLAST-CONTROL GMBHInventors: Stefan Konermann, Michael Gunther, Roland Pulch, Andreas Bartel, Markus Stein
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Patent number: 7531315Abstract: A polypeptide, called Tir (for translocated intimin receptor, which is secreted by attaching and effacing pathogens, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli. These bacterial pathogens inserts their own receptors into mammalian cell surfaces, to which the bacterial pathogen then adheres to trigger additional host signaling events and actin nucleation. Diagnosis of disease caused by pathogenic E. coli can be performed by the use of antibodies which bind to Tir to detect the protein or the use of nucleic acid probes for detection of nucleic acids encoding Tir polypeptide. Isolated nucleic acid sequences encoding Tir polypeptide, Tir peptides, a recombinant method for producing recombinant Tir, antibodies which bind to Tir, and a kit for the detection of Tir-producing E. coli are provided. A method of immunizing a host with Tir to induce a protective immune response to Tir or a second polypeptide of interest is also provided.Type: GrantFiled: November 9, 2006Date of Patent: May 12, 2009Assignee: The University of British ColumbiaInventors: Brett B. Finlay, Brendan Kenny, Rebekah DeVinney, Markus Stein
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Patent number: 7369255Abstract: Method for measuring thicknesses of a film, a foil or a material layer with a measuring head which is spaced away from the film and with which a capacitive thickness measurement is performed, in which an optical distance measurement is performed with a distance measuring device and a distance determined by the optical distance measurement is used in determining the film thickness in the capacitive thickness measurement.Type: GrantFiled: January 9, 2006Date of Patent: May 6, 2008Assignee: Plast-Control GmbHInventors: Stefan Konermann, Markus Stein
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Publication number: 20070218518Abstract: A polypeptide, called Tir (for translocated intimin receptor, which is secreted by attaching and effacing pathogens, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli. These bacterial pathogens inserts their own receptors into mammalian cell surfaces, to which the bacterial pathogen then adheres to trigger additional host signaling events and actin nucleation. Diagnosis of disease caused by pathogenic E. coli can be performed by the use of antibodies which bind to Tir to detect the protein or the use of nucleic acid probes for detection of nucleic acids encoding Tir polypeptide. Isolated nucleic acid sequences encoding Tir polypeptide, Tir peptides, a recombinant method for producing recombinant Tir, antibodies which bind to Tir, and a kit for the detection of Tir-producing E. coli are provided. A method of immunizing a host with Tir to induce a protective immune response to Tir or a second polypeptide of interest is also provided.Type: ApplicationFiled: November 9, 2006Publication date: September 20, 2007Applicant: The University of British ColumbiaInventors: Brett Finlay, Brendan Kenny, Rebekah DeVinney, Markus Stein
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Publication number: 20070213509Abstract: A polypeptide, called Tir (for translocated intimin receptor, which is secreted by attaching and effacing pathogens, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli. These bacterial pathogens inserts their own receptors into mammalian cell surfaces, to which the bacterial pathogen then adheres to trigger additional host signaling events and actin nucleation. Diagnosis of disease caused by pathogenic E. coli can be performed by the use of antibodies which bind to Tir to detect the protein or the use of nucleic acid probes for detection of nucleic acids encoding Tir polypeptide. Isolated nucleic acid sequences encoding Tir polypeptide, Tir peptides, a recombinant method for producing recombinant Tir, antibodies which bind to Tir, and a kit for the detection of Tir-producing E. coli are provided. A method of immunizing a host with Tir to induce a protective immune response to Tir or a second polypeptide of interst is also provided.Type: ApplicationFiled: November 9, 2006Publication date: September 13, 2007Applicant: The University of British ColumbiaInventors: Brett Finlay, Brendan Kenny, Rebekah DeVinney, Markus Stein
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Publication number: 20070184500Abstract: A polypeptide, called Tir (for translocated intimin receptor, which is secreted by attaching and effacing pathogens, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli. These bacterial pathogens inserts their own receptors into mammalian cell surfaces, to which the bacterial pathogen then adheres to trigger additional host signaling events and actin nucleation. Diagnosis of disease caused by pathogenic E. coli can be performed by the use of antibodies which bind to Tir to detect the protein or the use of nucleic acid probes for detection of nucleic acids encoding Tir polypeptide. Isolated nucleic acid sequences encoding Tir polypeptide, Tir peptides, a recombinant method for producing recombinant Tir, antibodies which bind to Tir, and a kit for the detection of Tir-producing E. coli are provided. A method of immunizing a host with Tir to induce a protective immune response to Tir or a second polypeptide of interest is also provided.Type: ApplicationFiled: November 9, 2006Publication date: August 9, 2007Applicant: The University of British ColumbiaInventors: Brett Finlay, Brendan Kenny, Rebekah DeVinney, Markus Stein
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Patent number: 7214499Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.Type: GrantFiled: April 25, 2006Date of Patent: May 8, 2007Assignee: University of British ColumbiaInventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai
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Patent number: 7208574Abstract: A polypeptide, called Tir (for translocated intimin receptor, which is secreted by attaching and effacing pathogens, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli. These bacterial pathogens inserts their own receptors into mammalian cell surfaces, to which the bacterial pathogen then adheres to trigger additional host signaling events and actin nucleation. Diagnosis of disease caused by pathogenic E. coli can be performed by the use of antibodies which bind to Tir to detect the protein or the use of nucleic acid probes for detection of nucleic acids encoding Tir polypeptide. Isolated nucleic acid sequences encoding Tir polypeptide, Tir peptides, a recombinant method for producing recombinant Tir, antibodies which bind to Tir, and a kit for the detection of Tir-producing E. coli are provided. A method of immunizing a host with Tir to induce a protective immune response to Tir or a second polypeptide of interest is also provided.Type: GrantFiled: November 10, 1998Date of Patent: April 24, 2007Assignee: The University of British ColumbiaInventors: B. Brett Finlay, Brendan Kenny, Rebekah DeVinney, Markus Stein
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Publication number: 20070010184Abstract: A tool exhibits a carrier part and a disc-shaped working part for chip-forming machining. The two parts are detachably connected with each other by means of a coupling part and a counter-coupling part that inter-lock. They exhibit convex and concave wall sections adapted to each other. Moreover, there is created a latch-in connection by an inside hexagon aperture and an outside hexagon.Type: ApplicationFiled: July 5, 2006Publication date: January 11, 2007Applicant: AUGUST RUGGEBERG GMBH & CO. KGInventors: Markus Stein, Nicolas Huth
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Publication number: 20060292180Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.Type: ApplicationFiled: April 25, 2006Publication date: December 28, 2006Applicant: The University of British ColumbiaInventors: B. Finlay, Brendan Kenny, Markus Stein, Michael Donnenberg, Li-Ching Lai