Patents by Inventor Markus Thomas

Markus Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BISPECIFIC, BIVALENT ANTI-VEGF/ANTI-ANG2 ANTIBODIES
    Publication number: 20150191535
    Abstract: The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: December 15, 2014
    Publication date: July 9, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Monika Baehner, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Kay-Gunnar Stubenrauch, Markus Thomas
  • Bispecific, bivalent anti-VEGF/anti-ANG-2 antibodies
    Patent number: 8945552
    Abstract: The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: February 3, 2015
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Monika Baehner, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas, Wolfgang Schaefer, Kay-Gunnar Stubenrauch, Markus Thomas
  • BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20150004166
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: February 27, 2014
    Publication date: January 1, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • Production and use of highly functional, highly branched or hyperbranched polylysines
    Patent number: 8846842
    Abstract: The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: September 30, 2014
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernd Bruchmann, Harm-Anton Klok, Markus Thomas Scholl
  • Bispecific anti-VEGF/anti-ANG-2 antibodies
    Patent number: 8703130
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: April 22, 2014
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • Production and use of highly functional, highly branched or hyperbranched polylysines
    Patent number: 8378049
    Abstract: The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: February 19, 2013
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernd Bruchmann, Harm-Anton Klok, Markus Thomas Scholl
  • BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20120321627
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: August 9, 2012
    Publication date: December 20, 2012
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • Bispecific anti-VEGF/anti-ANG-2 antibodies
    Patent number: 8268314
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: September 18, 2012
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • BISPECIFIC, BIVALENT ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20110236388
    Abstract: The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: March 24, 2011
    Publication date: September 29, 2011
    Inventors: Monika Baehner, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Kay-Gunnar Stubenrauch, Markus Thomas
  • Production and use of highly functional, highly branched or hyperbranched polylysines
    Publication number: 20100249369
    Abstract: The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use.
    Type: Application
    Filed: June 4, 2010
    Publication date: September 30, 2010
    Applicant: BASF SE
    Inventors: Bernd Bruchmann, Harm-Anton Klok, Markus Thomas Scholl
  • Production and use of highly functional, highly branched or hyperbranched polylysines
    Publication number: 20100222539
    Abstract: The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use.
    Type: Application
    Filed: May 6, 2010
    Publication date: September 2, 2010
    Applicant: BASF SE
    Inventors: Bernd Bruchmann, Harm-Anton Klok, Markus Thomas Scholl
  • Production and use of highly functional, highly branched or hyperbranched polylysines
    Patent number: 7786240
    Abstract: The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: August 31, 2010
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernd Bruchmann, Harm-Anton Klok, Markus Thomas Scholl
  • BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20100111967
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: October 2, 2009
    Publication date: May 6, 2010
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • DEVICE FOR THE CONTROLLED RELEASE OF A PREDEFINED QUANTITY OF A SUBSTANCE
    Publication number: 20100063485
    Abstract: Device for the controlled release of a predefined quantity of a substance and method for the production of a device for the controlled release of a predefined quantity of a substance. To realize a controlled delivery of a substance based upon a multiplicity of individual compartments, the reservoirs are formed in plastic substrates that allow the substance delivery device to be flexible and conformal with both internal and external body parts. The fabrication technology for the plastic drug release reservoirs is compatible with active matrix array technology, allowing control of delivery to be based upon active matrix principles. Applications are for controlled external drug delivery (patches), implantable drug delivery and oral drug delivery (electronic pill).
    Type: Application
    Filed: September 6, 2007
    Publication date: March 11, 2010
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Markus Thomas Johnson, Ian French, Marc Wilhelmus Gijsbert Ponjee
  • PRODUCTION AND USE OF HIGHLY FUNCTIONAL, HIGHLY BRANCHED OR HYPERBRANCHED POLYLYSINES
    Publication number: 20090048416
    Abstract: The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use.
    Type: Application
    Filed: November 15, 2006
    Publication date: February 19, 2009
    Applicant: BASF SE
    Inventors: Bernd Bruchmann, Harm-Anton Klok, Markus Thomas Scholl
  • Method of forming shaped articles made from pre-processed starch
    Patent number: 5405564
    Abstract: The invention refers to a process of forming shaped articles from starch, which process comprises:(a) heating a composition comprising a pre-processed and essentially destructurized starch/water material, at a water content in the range of from 10 to 20% by weight based on the weight of the composition to a temperature sufficient to essentially destructure the starch.(b) transferring the melt to a mold while maintaining said water content and(c) cooling the melt in the mold to a temperature below its glass transition temperature to form a solid shaped articleand articles made by this process.
    Type: Grant
    Filed: September 15, 1993
    Date of Patent: April 11, 1995
    Assignee: Warner-Lambert Company
    Inventors: Robert F. T. Stepto, Ivan Tomka, Markus Thoma
  • Polymer compositions containing destructurized starch
    Patent number: 5095054
    Abstract: A thermoplastic polymer composition comprising:(a) a destructurized starch, and either(b) an effective amount of at least one compound selected from the following: (1) a polymer which contains at least two different types of functional groups, one of said types of these groups being hydroxyl groups; (2) at least one polymer which does not contain hydroxyl groups and is selected from the group consisting of polymers which contain at least two types of functional groups bound to the same molecule one type of these groups being carboxylate groups; (3) at least one polymer selected from the group consisting of polymers which contain tertiary amino groups and/or salts thereof and/or quaternary ammonium groups; (4) at least one polymer selected from the group of polysaccharides which have been chemically modified to contain added hydroxyalkyl groups and/or contain alkyl ether groups, and/or contain ester groups; (5) at least one compound selected from the group consisting of copolymers of vinyl pyrrolidone; (6) at
    Type: Grant
    Filed: June 18, 1990
    Date of Patent: March 10, 1992
    Assignee: Warner-Lambert Company
    Inventors: Gustav Lay, Johannes Rehm, Robert F. Stepto, Markus Thoma, Jean-Pierre Sachetto, David J. Lentz, Jakob Silbiger