Patents by Inventor Markus WALDHUBER

Markus WALDHUBER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CANINE ANTIBODY LIBRARIES
    Publication number: 20230399381
    Abstract: The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries.
    Type: Application
    Filed: May 31, 2023
    Publication date: December 14, 2023
    Inventors: Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
  • MODIFIED FC REGIONS
    Publication number: 20230348577
    Abstract: The present invention relates to the field of modified constant domains of canine or feline antibodies having altered immune-effector functions and their use. More specifically, the application relates to modified Fc fragments having significantly reduced Fc?RI and C1q binding.
    Type: Application
    Filed: February 18, 2021
    Publication date: November 2, 2023
    Applicant: adivo GmbH
    Inventors: Verena BRAND, Christina SCHNEIDER, Andrea STERNER, Markus WALDHUBER
  • Antibodies to PMEL17 and conjugates thereof
    Patent number: 11779649
    Abstract: This application discloses anti-PMEL17 antibodies, antigen binding fragments thereof, and antibody drug conjugates comprising antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor. The application also discloses methods of treating or preventing cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: October 10, 2023
    Assignee: Novartis AG
    Inventors: Matthew Burger, Joseph Anthony D'Alessio, Tony Fleming, Vivek Rauniyar, Eusebio Manchado Robles, Christian Kunz, Markus Waldhuber
  • Canine antibody libraries
    Patent number: 11702463
    Abstract: The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries.
    Type: Grant
    Filed: April 22, 2021
    Date of Patent: July 18, 2023
    Assignee: MORPHOSYS AG
    Inventors: Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
  • TREM2 STABILIZING ANTIBODIES
    Publication number: 20230167174
    Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.
    Type: Application
    Filed: September 23, 2022
    Publication date: June 1, 2023
    Inventors: Verena BRAND, Dominik FEUERBACH, Fabrizio GASPARINI, Nathalie GEORGE, Eveline SCHAADT, Derya SHIMSHEK, Honnappa SRINIVAS, Markus WALDHUBER, Rainer WILCKEN
  • TREM2 stabilizing antibodies
    Patent number: 11492402
    Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: November 8, 2022
    Assignee: NOVARTIS AG
    Inventors: Verena Brand, Dominik Feuerbach, Fabrizio Gasparini, Nathalie George, Eveline Schaadt, Derya Shimshek, Honnappa Srinivas, Markus Waldhuber, Rainer Wilcken
  • FACTOR XI ANTIBODIES AND METHODS OF USE
    Publication number: 20220162339
    Abstract: The present disclosure relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI (“Factor XIa”), and pharmaceutical compositions and methods of treatment comprising the same.
    Type: Application
    Filed: October 6, 2021
    Publication date: May 26, 2022
    Inventors: Maximilian AIGNER, Alexander Wolfgang KOCH, Markus WALDHUBER
  • Factor XI antibodies and methods of use
    Patent number: 11168147
    Abstract: The present disclosure relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI (“Factor XIa”), and pharmaceutical compositions and methods of treatment comprising the same.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: November 9, 2021
    Assignee: NOVARTIS AG
    Inventors: Maximilian Aigner, Alexander Wolfgang Koch, Markus Waldhuber
  • CANINE ANTIBODY LIBRARIES
    Publication number: 20210317190
    Abstract: The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries.
    Type: Application
    Filed: April 22, 2021
    Publication date: October 14, 2021
    Inventors: Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
  • Canine antibody libraries
    Patent number: 11014978
    Abstract: The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: May 25, 2021
    Assignee: MORPHOSYS AG
    Inventors: Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
  • CANINE ANTIBODY LIBRARIES
    Publication number: 20200223904
    Abstract: The present invention provides synthetic canine antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries.
    Type: Application
    Filed: June 21, 2018
    Publication date: July 16, 2020
    Inventors: Thomas Tiller, Markus Waldhuber, Ralf Strohner, Kathrin Ladetzki-Baehs, Josef Prassler
  • TREM2 STABILIZING ANTIBODIES
    Publication number: 20200140545
    Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.
    Type: Application
    Filed: October 14, 2019
    Publication date: May 7, 2020
    Inventors: Verena BRAND, Dominik FEUERBACH, Fabrizio GASPARINI, Nathalie GEORGE, Eveline SCHAADT, Derya SHIMSHEK, Honnappa SRINIVAS, Markus WALDHUBER, Rainer WILCKEN
  • FACTOR XI ANTIBODIES AND METHODS OF USE
    Publication number: 20190330372
    Abstract: The present disclosure relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI (“Factor XIa”), and pharmaceutical compositions and methods of treatment comprising the same.
    Type: Application
    Filed: December 21, 2017
    Publication date: October 31, 2019
    Inventors: Maximillian AIGNER, Alexander Wolfgang KOCH, Markus WALDHUBER