Patents by Inventor Markus Wallgren
Markus Wallgren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230280308Abstract: A nanopore based sequencing system includes a plurality of nanopore sensors. Each nanopore sensor has a portion for receiving a fluid. The nanopore based sequencing system includes a fluid chamber configured to guide the fluid over the plurality of nanopore sensors and an inlet configured to deliver the fluid into the fluid chamber. At least a portion of the fluid chamber is made of a material that has been molded around at least a portion of an electrode.Type: ApplicationFiled: May 12, 2023Publication date: September 7, 2023Inventors: Edward Liu, Kenneth M. Stothers, Markus Wallgren, Janusz B. Wojtowicz, Robert A. Yuan
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Patent number: 11686706Abstract: A nanopore based sequencing system includes a plurality of nanopore sensors. Each nanopore sensor has a portion for receiving a fluid. The nanopore based sequencing system includes a fluid chamber configured to guide the fluid over the plurality of nanopore sensors and an inlet configured to deliver the fluid into the fluid chamber. At least a portion of the fluid chamber is made of a material that has been molded around at least a portion of an electrode.Type: GrantFiled: July 15, 2020Date of Patent: June 27, 2023Assignee: Roche Sequencing Solutions, Inc.Inventors: Edward Liu, Kenneth M. Stothers, Markus Wallgren, Janusz B. Wojtowicz, Robert A. Yuan
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Publication number: 20220299472Abstract: A nanopore based sequencing chip package is disclosed. The nanopore based sequencing chip package includes a reservoir defined by a plurality of surfaces. The chip package includes a nanopore cell array comprising a plurality of nanopore sensor cells enclosed by the reservoir. Each nanopore sensor cell has a working electrode. At least one surface of the reservoir is configured to be in contact with a conducting fluid when the conducting fluid is flowing through the reservoir. The chip package further includes a counter electrode disposed on the at least one surface of the reservoir.Type: ApplicationFiled: June 2, 2022Publication date: September 22, 2022Inventors: J. William Maney, JR., David Bruce Robinson, Markus Wallgren, Robert A. Yuan
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Publication number: 20200348261Abstract: A nanopore based sequencing system includes a plurality of nanopore sensors. Each nanopore sensor has a portion for receiving a fluid. The nanopore based sequencing system includes a fluid chamber configured to guide the fluid over the plurality of nanopore sensors and an inlet configured to deliver the fluid into the fluid chamber. At least a portion of the fluid chamber is made of a material that has been molded around at least a portion of an electrode.Type: ApplicationFiled: July 15, 2020Publication date: November 5, 2020Inventors: Edward Liu, Kenneth M. Stothers, Markus Wallgren, Janusz B. Wojtowicz, Robert A. Yuan
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Patent number: 10718737Abstract: A nanopore based sequencing system includes a plurality of nanopore sensors. Each nanopore sensor has a portion for receiving a fluid. The nanopore based sequencing system includes a fluid chamber configured to guide the fluid over the plurality of nanopore sensors and an inlet configured to deliver the fluid into the fluid chamber. At least a portion of the fluid chamber is made of a material that has been molded around at least a portion of an electrode.Type: GrantFiled: January 19, 2017Date of Patent: July 21, 2020Assignee: Roche Sequencing Solutions, Inc.Inventors: Robert A. Yuan, Janusz B. Wojtowicz, Edward Liu, Kenneth M. Stothers, Markus Wallgren
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Publication number: 20190256904Abstract: A method for sequencing a nucleic acid molecule includes providing a sequencing cell (200) having a nanopore (216) in a membrane (214) that resides over a well (205), a first electrode (202) at a bottom of the well, a second electrode (210) in a chamber (215) above the membrane, and an electrolyte (206, 208) in the well (205) and the chamber (215). The first electrode (202) is configured to facilitate non-Faradaic conduction of ionic current and forms a capacitance with ions in the electrolyte. A first voltage signal (1310) is applied across the first and second electrodes (202, 210), thereby creating a force that moves a nucleic acid molecule in the sequence cell through the nanopore (216). The first voltage signal (1310) increases to compensate for changes in the capacitance at the first electrode (202) during application of the first voltage signal.Type: ApplicationFiled: October 10, 2017Publication date: August 22, 2019Inventors: Randall DAVIS, Markus WALLGREN
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Patent number: 10371664Abstract: A nanopore cell includes a titanium nitride (TiN) counter electrode configured to be at a first electric potential. The nanopore cell also include a working electrode configured to be at a second electric potential and an insulating wall. The insulating wall and the working electrode form at least a portion of a well configured to contain an electrolyte at a voltage that is at least a portion of an electric potential difference between the first electric potential of the titanium nitride counter electrode and the second electric potential of the working electrode.Type: GrantFiled: January 19, 2017Date of Patent: August 6, 2019Assignee: Roche Molecular Systems, Inc.Inventors: Markus Wallgren, Janusz B. Wójtowicz, Robert A. Yuan, John Foster, Jason Komadina
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Publication number: 20170284962Abstract: A nanopore based sequencing chip package is disclosed. The nanopore based sequencing chip package includes a reservoir defined by a plurality of surfaces. The chip package includes a nanopore cell array comprising a plurality of nanopore sensor cells enclosed by the reservoir. Each nanopore sensor cell has a working electrode. At least one surface of the reservoir is configured to be in contact with a conducting fluid when the conducting fluid is flowing through the reservoir. The chip package further includes a counter electrode disposed on the at least one surface of the reservoir.Type: ApplicationFiled: April 14, 2017Publication date: October 5, 2017Inventors: J. William Maney, David Bruce Robinson, Markus Wallgren, Robert A. Yuan
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Publication number: 20170212078Abstract: A nanopore based sequencing system includes a plurality of nanopore sensors. Each nanopore sensor has a portion for receiving a fluid. The nanopore based sequencing system includes a fluid chamber configured to guide the fluid over the plurality of nanopore sensors and an inlet configured to deliver the fluid into the fluid chamber. At least a portion of the fluid chamber is made of a material that has been molded around at least a portion of an electrode.Type: ApplicationFiled: January 19, 2017Publication date: July 27, 2017Inventors: Robert A. Yuan, Janusz B. Wójtowicz, Edward Liu, Kenneth M. Stothers, Markus Wallgren
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Publication number: 20170212079Abstract: A nanopore cell includes a titanium nitride (TiN) counter electrode configured to be at a first electric potential. The nanopore cell also include a working electrode configured to be at a second electric potential and an insulating wall. The insulating wall and the working electrode form at least a portion of a well configured to contain an electrolyte at a voltage that is at least a portion of an electric potential difference between the first electric potential of the titanium nitride counter electrode and the second electric potential of the working electrode.Type: ApplicationFiled: January 19, 2017Publication date: July 27, 2017Inventors: Markus Wallgren, Janusz B. Wójtowicz, Robert A. Yuan, John Foster, Jason Komadina
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Patent number: 9658190Abstract: A nanopore based sequencing chip package is disclosed. The nanopore based sequencing chip package includes a reservoir defined by a plurality of surfaces. The chip package includes a nanopore cell array comprising a plurality of nanopore sensor cells enclosed by the reservoir. Each nanopore sensor cell has a working electrode. At least one surface of the reservoir is configured to be in contact with a conducting fluid when the conducting fluid is flowing through the reservoir. The chip package further includes a counter electrode disposed on the at least one surface of the reservoir.Type: GrantFiled: December 18, 2014Date of Patent: May 23, 2017Assignee: Genia Technologies, Inc.Inventors: Bill Maney, David Bruce Robinson, Markus Wallgren, Robert A. Yuan
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Publication number: 20160178576Abstract: A nanopore based sequencing chip package is disclosed. The nanpore based sequencing chip package includes a reservoir defined by a plurality of surfaces. The chip package includes a nanopore cell array comprising a plurality of nanopore sensor cells enclosed by the reservoir. Each nanopore sensor cell has a working electrode. At least one surface of the reservoir is configured to be in contact with a conducting fluid when the conducting fluid is flowing through the reservoir. The chip package further includes a counter electrode disposed on the at least one surface of the reservoir.Type: ApplicationFiled: December 18, 2014Publication date: June 23, 2016Inventors: Bill Maney, David Bruce Robinson, Markus Wallgren, Robert A. Yuan
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Patent number: 6680601Abstract: A power mediation method and circuit for powering a communications controller based device using battery cells that exhibit non stable power delivery characteristics. The use of a servo-loop creates an energy potential in an energy storage element and maintains that required energy potential using the functionality of the communications controller that concurrently draws required power from the energy storage element.Type: GrantFiled: May 31, 2002Date of Patent: January 20, 2004Assignee: Telespree CommunicationsInventor: Markus Wallgren
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Publication number: 20030222625Abstract: A power mediation method and circuit for powering a communications controller based device using battery cells that exhibit non stable power delivery characteristics. The use of a servo-loop creates an energy potential in an energy storage element and maintains that required energy potential using the functionality of the communications controller that concurrently draws required power from the energy storage element.Type: ApplicationFiled: May 31, 2002Publication date: December 4, 2003Inventor: Markus Wallgren
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Patent number: 5420493Abstract: An integrated AC adapter and battery charger is disclosed. The apparatus comprises an AC adapter unit for converting AC power to a DC power and a battery charging apparatus coupled to the AC adapter unit for charging a battery pack. The battery charging apparatus further comprises a microcontroller for sensing the condition of the battery pack or tacks being charged, a memory for storing the proper charging profile for a number of different types of battery packs, and a charging current generator capable of generating a varying charging current based on the microcontroller's determination of the battery's condition and the charging profile stored in the memory.Type: GrantFiled: June 30, 1992Date of Patent: May 30, 1995Assignee: Apple Computer, Inc.Inventors: Andrew Hargadon, Steven J. Young, Kihachiro Tonomura, Markus Wallgren, Mark Gurries
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Patent number: 5254928Abstract: A power management system for a portable computer is disclosed. The system can determine which one of a plurality of battery packs has been coupled to the system. After determining the type of battery pack, the system recalls from storage the recommended charging pattern for the particular battery pack and begins to charge the battery at the recommended rate. The system's information is used during charging to determine if the battery pack is defective. When the computer is running off the battery pack, the charge counter measures the total amount of charge supplied to the computer and provides this information to the system. When the difference betweem the total amount of charge supplied to the computer and the total charge available from the battery reaches a predefined limit, the system indicates to the computer that a low-power situation exists and that the computer should prepare for a possible loss-of-power event.Type: GrantFiled: October 1, 1991Date of Patent: October 19, 1993Assignee: Apple Computer, Inc.Inventors: Steven J. Young, Markus Wallgren