Patents by Inventor Markus ZETTL

Markus ZETTL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY MOLECULES FOR CANCER TREATMENT
    Publication number: 20240124581
    Abstract: The present invention relates to novel anti-PD1 and anti-LAG3 antibody molecules. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: September 1, 2023
    Publication date: April 18, 2024
    Inventors: Markus ZETTL, Ivo LORENZ, Otmar SCHAAF, Melanie WURM, Jean-Francois FORTIN, Scott Ronald BRODEUR, Keith A. CANADA, Lukasz CHLEWICKI, Walter Carroll DAVIDSON, Pankaj GUPTA, Priyanka GUPTA, Rocío K. PÉREZ, Joseph Robert WOSKA, Jr., Haiguang XIAO, Danlin YANG
  • BIOMARKER METHODS AND USES
    Publication number: 20230366884
    Abstract: The disclosure provides methods for predicting a positive clinical outcome for a cancer patient upon treatment with a 4-1BB agonistic agent, for assessing activity of such 4-1BB agonistic agent in a subject, preferably a cancer patient, and for selecting a dose of a 4-1BB agonistic agent for treating a disease, such as cancer. The disclosure also provides methods of treating cancer as well as uses of biomarkers and uses of kits for their detection.
    Type: Application
    Filed: September 17, 2021
    Publication date: November 16, 2023
    Inventors: Markus ZETTL, Aizea Morales KASTRESANA, Cornelia WURZENBERGER, Janet PEPER-GABRIEL, Marleen RICHTER, Nicole ANDERSEN, Rachida BEL AIBA, Andrea ALLERSDORFER, Verena NODERER
  • Antibody molecules for cancer treatment
    Patent number: 11795219
    Abstract: The present invention relates to novel anti-PD1 and anti-LAG3 antibody molecules. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: October 24, 2023
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Markus Zettl, Ivo Lorenz, Otmar Schaaf, Melanie Wurm, Jean-Francois Fortin, Scott Ronald Brodeur, Keith A. Canada, Lukasz Chlewicki, Walter Carroll Davidson, Pankaj Gupta, Priyanka Gupta, Rocío K. Pérez, Joseph Robert Woska, Jr., Haiguang Xiao, Danlin Yang
  • Antagonizing CD73 antibody
    Patent number: 11312785
    Abstract: The present invention relates to novel antagonizing antibodies for CD73. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: April 26, 2022
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Irmgard Maria Rita Hofmann, Jennifer Ahlberg, Rajkumar Ganesan, Priyanka Gupta, Sven Mostboeck, Simon Plyte, Otmar Schaaf, Chia-Hung Tsai, Melanie Wurm, Markus Zettl, Jark Boettcher, Bruna De Andrade Pereira
  • Antibody molecules for cancer treatment
    Patent number: 11028169
    Abstract: The present invention relates to novel anti-PD1 and anti-LAG3 antibody molecules. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: June 8, 2021
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Markus Zettl, Ivo Lorenz, Otmar Schaaf, Melanie Wurm, Jean-Francois Fortin, Scott Ronald Brodeur, Keith A. Canada, Lukasz Chlewicki, Priyanka Gupta, Rocío K. Pérez, Joseph Robert Woska, Haiguang Xiao, Danlin Yang
  • ANTIBODY MOLECULES FOR CANCER TREATMENT
    Publication number: 20210095020
    Abstract: The present invention relates to novel anti-PD1 and anti-LAG3 antibody molecules. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: May 11, 2020
    Publication date: April 1, 2021
    Inventors: Markus ZETTL, Ivo LORENZ, Otmar SCHAFF, Melanie WURM, Jean-Francois FORTIN, Scott Ronald BRODEUR, Keith A. CANADA, Lukasz CHLEWICKI, Walter Carroll DAVIDSON, Pankaj GUPTA, Priyanka GUPTA, Rocío K. PÉREZ, Joseph Robert WOSKA, JR., Haiguang XIAO, Danlin YANG
  • Antagonizing CD73 Antibody
    Publication number: 20190352420
    Abstract: The present invention relates to novel antagonizing antibodies for CD73. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: May 13, 2019
    Publication date: November 21, 2019
    Inventors: Irmgard Maria Rita HOFMANN, Jennifer AHLBERG, Rajkumar GANESAN, Priyanka Gupta, Sven MOSTBOECK, Simon PLYTE, Otmar SCHAAF, Chia-Hung TSAI, Melanie WURM, Markus ZETTL, Jark BOETTCHER, Bruna DE ANDRADE PEREIRA
  • ANTIBODY MOLECULES FOR CANCER TREATMENT
    Publication number: 20170334995
    Abstract: The present invention relates to novel anti-PD1 and anti-LAG3 antibody molecules. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: May 18, 2017
    Publication date: November 23, 2017
    Inventors: Markus ZETTL, Ivo LORENZ, Otmar SCHAFF, Melanie WURM, Jean-Francois FORTIN, Scott Ronald BRODEUR, Keith A. CANADA, Lukasz CHLEWICKI, Walter Carroll DAVIDSON, Pankaj GUPTA, Priyanka GUPTA, Rocío K. PÉREZ, Joseph Robert WOSKA, Jr., Haiguang XIAO, Danlin YANG