Abstract: The invention relates to substituted S-alaninate derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.

Abstract: A method for interactions during encounters between a mobile robot and an actor, a mobile robot configured for execution of delivery tasks in an outdoor environment, and a use of the mobile robot. The method comprises the mobile robot traveling on a pedestrian pathway; detecting an actor by the mobile robot via a sensor system; identifying a situation associated with the detected actor; in response to the identified situation, determining an action to execute by the mobile robot, and executing the determined action by the mobile robot. The mobile robot comprises a navigation component configured for at least partially autonomous navigation in an outdoor environment; a sensor system configured for collecting sensor data during an encounter between the mobile robot and an actor; a processing component configured to process the sensor data and output actions for the mobile robot to perform; and an output component configured for executing actions determined by the processing component.

Abstract: A filling device for dosed filling of a product from a product storage container into product dose receiving containers provided in a disposable isolator so to be protected against contamination. The device includes means for holding the product storage container together with the contents outside of the disposable isolator. The device includes a controllable product removal device for a dosed removal of the product from the product storage container. The device includes a product dispensing device for the dosed dispensing of the product to the product dose receiving containers. The device includes a line assembly interconnecting the product storage container and the product dispensing device to conduct the product to the product dispensing device. The device includes at least one ultrasonic flowmeter outside of the disposable isolator fixed to the outside of the line assembly to detect the flow rate. The device includes a controller for measuring the product dose.

Abstract: A vaporizer device for vaporizing a liquid and/or an aerosol, has at least one housing comprising at least one vaporizer space housing, which delimits a vaporizer space into which the liquid to be vaporized and/or the aerosol to be vaporized can be fed, and has at least one heating unit for a vaporization of the fed-in liquid and/or the fed-in aerosol, wherein the heating unit is realized as a matrix heating unit comprising a plurality of heating elements, which can be regulated and/or monitored separately, wherein the heating unit comprises the plurality of heating elements which are arranged irregularly and/or regularly in a plane, wherein the plurality of heating elements are arranged at a heating plate of the heating unit, wherein a surface of the heating plate forms a vaporizer surface of the heating unit for a vaporization of the liquid and/or of an aerosol.

Abstract: A mobile robot configured for vending consumable items. A system configured for vending consumable items comprising a mobile robot, a vending terminal, and a server communicating with each of the other two. A method for vending consumable items using a mobile robot. A method for on-demand consumable item delivery by a mobile robot.

Abstract: A filling device for metered filling of a filling material from a storage container into a dose receiving container. The device includes a single-use isolator with the receiving container provided therein to protect against contamination. The device includes a weighing device for holding and weighing the storage container with its contents outside of the isolator. The device includes a dispensing device inside the isolator to provide a dose-by-dose dispensing of the material. The device includes a conduit arrangement for connecting the storage container and the dispensing device and conveying the material from the storage container to the dispensing device via a removal device for a dose-by-dose removal of the material outside the isolator. The device includes a control device for controlling the removal device based on information from the weighing device about a decrease in weight of a unit consisting of the storage container and its contents during the removal.

Abstract: A filling device for dosed filling of a product from a product storage container into product dose receiving containers provided in a disposable isolator so to be protected against contamination. The device includes means for holding the product storage container together with the contents outside of the disposable isolator. The device includes a controllable product removal device for a dosed removal of the product from the product storage container. The device includes a product dispensing device for the dosed dispensing of the product to the product dose receiving containers. The device includes a line assembly interconnecting the product storage container and the product dispensing device to conduct the product to the product dispensing device. The device includes at least one ultrasonic flowmeter outside of the disposable isolator fixed to the outside of the line assembly to detect the flow rate. The device includes a controller for measuring the product dose.

Abstract: A production device including an isolator housing to receive functional components of the production device and products in an interior of the production device and to hermetically seal the components from the surroundings. The production device includes at least one robot received in the isolator housing, wherein the robot is one or more of operable to carry out specific tasks or operable to be remotely controllable by means of a remote controller. The production device includes at least one linear movement unit received in the isolator housing and configured to move the at least one robot long a linear movement axis. The production device includes at least one control unit to control one or more of a movement or an operation of the at least one robot.

Abstract: A mobile robot is configured for vending consumable items. The robot includes a mobile base; a body comprising an item space; a plurality of support elements located in the item space and configured to support consumable items; an item sensor configured to detect presence of one or more consumable items supported by each of the support elements; and an insert configured to removably fit into the item space, and wherein the insert comprises the support elements and the item sensor. A method for vending consumable items uses the mobile robot.

Abstract: Disclosed are a method for interactions during encounters between a mobile robot and an actor, a mobile robot configured for execution of delivery tasks in an outdoor environment, and a use of the mobile robot. The method comprises the mobile robot travelling on a pedestrian pathway; detecting an actor by the mobile robot via a sensor system; identifying a situation associated with the detected actor; in response to the identified situation, determining an action to execute by the mobile robot; and executing the determined action by the mobile robot. The mobile robot comprises a navigation component configured for at least partially autonomous navigation in outdoor environment; a sensor system configured for collecting sensor data during an encounter between the mobile robot and an actor; a processing component configured to process the sensor data and output actions for the mobile robot to perform; and an output component configured for executing actions determined by the processing component.

Abstract: A signaling device for increasing visibility of a mobile robot. The signaling device comprises (a) a base section, attached with a rotational joint to a side of the mobile robot, said rotational joint allowing the device to rotate clockwise and/or anticlockwise relative to the mobile robot, the rotational joint constructed and adapted to return the device to an equilibrium position; and (b) a body section comprising a mast, the body section flexibly attached to the base section at a lower extreme of the body section.

Abstract: A signaling device for increasing visibility of a mobile robot. The signaling device comprises a signaling section, a body section, and a base section. The invention also discloses a system for increasing visibility of a mobile robot. The system comprises a mobile robot, a signaling device attached to the mobile robot and a remote terminal configured to at least one of monitoring and controlling at least one of the mobile robot and the signaling device.

Abstract: A method for determining a reference focal position of a laser beam for processing a plate-like member, the method comprising producing at least two incisions in the plate-like member with the laser beam set at different focal positions, irradiating the plate-like member with the laser beam, detecting edges of the incisions by measuring one or more parameters relating to the irradiation of the plate-like member, and establishing a width of the at least two incisions using the detected one or more parameters.

Abstract: A mobile robot has a body having at least one item space; a lid constructed and adapted to assume at least an open position and a closed position, wherein the lid is to fit on top of the body in the closed position, so as to cover the item space, and the lid is to be lifted to the open position, so as to allow access to the item space; at least four wheels; and a plurality of light sources arranged as at least one row of lights.

Abstract: A mobile robot configured for vending consumable items. A system configured for vending consumable items comprising a mobile robot, a vending terminal, and a server communicating with each of the other two. A method for vending consumable items using a mobile robot. A method for on-demand consumable item delivery by a mobile robot.

Abstract: A signaling device for increasing visibility of a mobile robot. The signaling device comprises a signaling section, a body section, and a base section. The invention also discloses a system for increasing visibility of a mobile robot. The system comprises a mobile robot, a signaling device attached to the mobile robot and a remote terminal configured to at least one of monitoring and controlling at least one of the mobile robot and the signaling device.

Abstract: A method for determining a reference focal position of a laser beam for processing a plate-like member, the method comprising producing at least two incisions in the plate-like member with the laser beam set at different focal positions, irradiating the plate-like member with the laser beam, detecting edges of the incisions by measuring one or more parameters relating to the irradiation of the plate-like member, and establishing a width of the at least two incisions using the detected one or more parameters.

Abstract: This disclosure relates to methods and apparatuses for marking a data matrix code in the form of an n*m cell matrix of light and dark cells, which respectively consist of a light or dark s*t pixel matrix, on a workpiece by a laser beam, wherein a laser processing unit directs the laser beam onto the workpiece, scans, pixel row by pixel row, the workpiece region to be marked, respectively with a constant marking speed and alternately in opposite directions, and wherein the light pixels and/or the dark pixels are marked on the workpiece during the scan by temporarily switching on the laser beam, wherein the laser processing unit is guided from an already scanned pixel row along a curve having a diameter of which is at least two times the pixel row spacing, to the next pixel row to be scanned.

Abstract: A vehicle having an internal combustion engine mounted in the vehicle such that a crankshaft of the internal combustion engine runs in a longitudinal direction of the vehicle is provided with a flexible drive is provided that comprises a wheel, in particular a pulley, which is arranged such as to rotate about a longitudinal axis of the vehicle and which is arranged in front of the internal combustion engine when viewed in the direction of travel of the vehicle. The wheel has at least one weakened section which allows or facilitates a compression of the wheel in the longitudinal direction of the vehicle upon a head-on collision. In addition, the wheel may be arranged to cooperate with a recess in the front of the engine to permit further displacement of the wheel toward the engine during a collision.

Abstract: This disclosure relates to methods and apparatuses for marking a data matrix code in the form of an n*m cell matrix of light and dark cells, which respectively consist of a light or dark s*t pixel matrix, on a workpiece by a laser beam, wherein a laser processing unit directs the laser beam onto the workpiece, scans, pixel row by pixel row, the workpiece region to be marked, respectively with a constant marking speed and alternately in opposite directions, and wherein the light pixels and/or the dark pixels are marked on the workpiece during the scan by temporarily switching on the laser beam, wherein the laser processing unit is guided from an already scanned pixel row along a curve having a diameter of which is at least two times the pixel row spacing, to the next pixel row to be scanned.