Patents by Inventor Marlen Schmidt

Marlen Schmidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICROORGANISM STRAIN FOR ANTIBIOTIC-FREE PLASMID-BASED FERMENTATION AND METHOD FOR GENERATION THEREOF
    Publication number: 20250179506
    Abstract: The present invention relates to means for recombinant manufacture. In particular, it relates to a recombinant bacterial cell comprising in its genome at least one essential gene the endogenous promoter of which has been replaced by a heterologous expression control sequence being inducible by an inducer molecule, such that the expression of said essential gene in the recombinant bacterial cell is dependent on the presence of said inducer molecule. Further contemplated are methods for generating the recombinant bacterial cell of the invention as well as a method for recombinant manufacture of a compound of interest. The present invention also provides for use the recombinant bacterial cell of the invention for recombinant manufacture of a compound of interest and a kit for manufacture of a compound of interest.
    Type: Application
    Filed: March 2, 2023
    Publication date: June 5, 2025
    Inventors: Harald KRANZ, Marlen SCHMIDT, Katherine Emily BRECHUN, Marion FOERSCHLE
  • MICROORGANISM STRAIN AND METHOD FOR ANTIBIOTIC-FREE PLASMID-BASED FERMENTATION
    Publication number: 20240271084
    Abstract: The present invention relates to means for recombinant manufacture. In particular, it relates to a recombinant bacterial cell comprising in its genome (i) at least one endogenous essential gene which is inactivated, and (ii) at least one introduced copy of the said at least one essential gene, wherein said introduced copy is operatively linked to a heterologous expression control sequence being inducible by an inducer molecule, such that the expression of said essential gene in the recombinant bacterial cell is dependent on the presence of said inducer molecule. The present invention, further relates to a method for generating the recombinant bacterial cell, a method for recombinant manufacture of a compound of interest and the use of a recombinant bacterial cell for the manufacture of a compound of interest. Moreover, the invention provides a kit for recombinant manufacture of a compound of interest.
    Type: Application
    Filed: May 19, 2022
    Publication date: August 15, 2024
    Inventors: Harald KRANZ, Marlen SCHMIDT, Marion FOERSCHLE
  • Esterases and their use for processes for kinetic resolution of butinolesters
    Patent number: 7704705
    Abstract: New enzymes having esterase activity and their use for processes for kinetic resolution of butinolesters.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: April 27, 2010
    Assignee: BASF SE
    Inventors: Uwe T. Bornscheuer, Marlen Schmidt, Markus Kaehler, Andre Rieks
  • Esterases and their Use for Processes for Kinetic Resolution of Butinolesters
    Publication number: 20090155865
    Abstract: New enzymes having esterase activity and their use for processes for kinetic resolution of butinolesters.
    Type: Application
    Filed: October 5, 2006
    Publication date: June 18, 2009
    Applicant: BASF Aktiengesellschaft
    Inventors: Uwe T. Bornscheuer, Marlen Schmidt, Markus Kaehler, Andre Rieks