Patents by Inventor Marlene Bainbridge

Marlene Bainbridge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10585085
    Abstract: Embodiments are described for separating/collecting components from a multi-component fluid such as whole blood. Some embodiments provide for controlling the amount of a component, such as platelets, introduced into a separation chamber to ensure that the density of fluid in the separation chamber does not exceed a particular value. This may provide for collecting purer components. Other embodiments may provide for determining a chamber flow rate based on a concentration of a component in the multi-component fluid, which may then be used to determine a centrifuge speed, to collect purer concentrated components.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: March 10, 2020
    Assignee: Terumo BCT, Inc.
    Inventors: Marlene Bainbridge, Todd Curtis Green, Logan Fender
  • Publication number: 20180106778
    Abstract: Embodiments are described for separating/collecting components from a multi-component fluid such as whole blood. Some embodiments provide for controlling the amount of a component, such as platelets, introduced into a separation chamber to ensure that the density of fluid in the separation chamber does not exceed a particular value. This may provide for collecting purer components. Other embodiments may provide for determining a chamber flow rate based on a concentration of a component in the multi-component fluid, which may then be used to determine a centrifuge speed, to collect purer concentrated components.
    Type: Application
    Filed: October 13, 2017
    Publication date: April 19, 2018
    Applicant: Terumo BCT, Inc.
    Inventors: Marlene BAINBRIDGE, Todd Curtis GREEN, Logan FENDER
  • Patent number: 7354415
    Abstract: Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extra-corporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: April 8, 2008
    Assignee: Gambro BCT, Inc.
    Inventors: Marlene Bainbridge, Muriel Keller, Timothy M. Gordon, Michael J. McAteer, Scott D. Butzke
  • Publication number: 20070232980
    Abstract: This invention provides an apparatus and method for controlling a fluid separation system, preferably a blood apheresis system, by sensing fluid pressure and comparing the sensed fluid pressure to a threshold value.
    Type: Application
    Filed: June 11, 2007
    Publication date: October 4, 2007
    Applicant: GAMBRO BCT, INC.
    Inventors: Thomas FELT, Marlene BAINBRIDGE
  • Publication number: 20070093774
    Abstract: This invention provides a method for controlling a fluid separation system, preferably a blood apheresis system having a leukocyte reduction chamber. The method utilizes at least a two-level alarm system. A first-level alarm condition is triggered in response to a pressure drop in the system to less than or equal to a specified system pressure and pauses fluid flow in at least a portion of the system. A second-level alarm condition is triggered in response to a specified number of said pressure drops within a specified period and reduces the flow rate of the fluid in the system. The alarm conditions may also trigger a visible and/or audible alarm. These alarm levels permit flow through the leukocyte reduction chamber to continue when the pressure drop is caused by a non-serious, self-resolving or easily-correctable condition such as misalignment of system components.
    Type: Application
    Filed: September 8, 2006
    Publication date: April 26, 2007
    Applicant: GAMBRO, INC.
    Inventors: Thomas Felt, Marlene Bainbridge
  • Publication number: 20070078368
    Abstract: This invention provides a method for controlling a fluid separation system, preferably a blood apheresis system having a leukocyte reduction chamber. The method utilizes a return-flow alarm system. A return-flow alarm-triggering pressure is specified, and when pressure of the return flow in the system is higher than or equal to the specified pressure, a return-flow alarm is triggered.
    Type: Application
    Filed: September 8, 2006
    Publication date: April 5, 2007
    Applicant: GAMBRO, INC.
    Inventors: Thomas Felt, Marlene Bainbridge
  • Publication number: 20070004997
    Abstract: This invention provides a method for controlling a fluid separation system, preferably a blood apheresis system having a leukocyte reduction chamber. The method utilizes a three-level alarm system. A first-level alarm condition is triggered in response to a pressure drop in the system to less than or equal to a specified system pressure and pauses fluid flow in at least a portion of the system. A second-level alarm condition is triggered in response to a specified number of said pressure drops within a specified period and reduces the flow rate of the fluid in the system. The alarm conditions may also trigger a visible and/or audible alarm. These alarm levels permit flow through the leukocyte reduction chamber to continue when the pressure drop is caused by a non-serious, self-resolving or easily-correctable condition such as misalignment of system components.
    Type: Application
    Filed: September 8, 2006
    Publication date: January 4, 2007
    Applicant: GAMBRO, INC.
    Inventors: Thomas Felt, Marlene Bainbridge
  • Patent number: 6945948
    Abstract: Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extra-corporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: September 20, 2005
    Assignee: Gambro, Inc.
    Inventors: Marlene Bainbridge, Muriel Keller, Timothy M. Gordon, Michael J. McAteer, Scott D. Butzke
  • Patent number: 6899691
    Abstract: A method and apparatus for controlling a fluid separation system in response to fluid pressure changes in a fluid flow, said method comprising the steps of sensing a fluid pressure; comparing the fluid pressure to a threshold value, and if the fluid pressure is below the threshold value, then pausing fluid flow for a selected period. During the selected period, either the fluid pressure sensed automatically resolves or the method further comprises a step of setting a fall alarm condition. The method and apparatus may further include interpreting a particular quantity of below threshold fluid pressure occurrences where the fluid pressure is below the threshold value occurring within a particular time period, and then, signalling an alarm. Threshold values may be calculated by the method or apparatus according to a formula such as the following: Threshold Value=Config+75?0.3309*Qin/(1?Hin)?0.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: May 31, 2005
    Assignee: Gambro Inc.
    Inventors: Marlene A. Bainbridge, Thomas J. Felt
  • Publication number: 20040249332
    Abstract: Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extra-corporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
    Type: Application
    Filed: April 20, 2004
    Publication date: December 9, 2004
    Applicant: GAMBRO, INC.
    Inventors: Marlene Bainbridge, Muriel Keller, Timothy M. Gordon, Michael J. McAteer, Scott D. Butzke
  • Publication number: 20040230152
    Abstract: Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extra-corporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
    Type: Application
    Filed: April 20, 2004
    Publication date: November 18, 2004
    Applicant: GAMBRO, INC.
    Inventors: Marlene Bainbridge, Muriel Keller, Timothy M. Gordon, Michael J. McAteer, Scott D. Butzke
  • Patent number: 6773413
    Abstract: An extracorporeal blood processing method includes a set-up phase establishing certain conditions in blood being processed prior to separation of the blood into components. Also, a blood processing method contemporaneously extracts selected multiple blood components from a blood processing vessel. Blood is separated into components in the blood processing vessel in a centrifugal field. Further, an extracorporeal blood processing method establishes a packing factor in the blood processing vessel prior to collecting red blood cells.
    Type: Grant
    Filed: December 4, 2000
    Date of Patent: August 10, 2004
    Assignee: Gamero Inc
    Inventors: Muriel Keller, Marlene Bainbridge
  • Patent number: 6730055
    Abstract: Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extracorporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
    Type: Grant
    Filed: March 9, 2001
    Date of Patent: May 4, 2004
    Assignee: Gambro Inc.
    Inventors: Marlene Bainbridge, Muriel Keller, Timothy M. Gordon, Michael J. McAteer, Scott D. Butzke
  • Publication number: 20020033370
    Abstract: Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extracorporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
    Type: Application
    Filed: March 9, 2001
    Publication date: March 21, 2002
    Inventors: Marlene Bainbridge, Muriel Keller, Timothy M. Gordon, Michael J. McAteer, Scott D. Butzke
  • Publication number: 20010048892
    Abstract: A method and apparatus for controlling a fluid separation system in response to fluid pressure changes in a fluid flow, said method comprising the steps of sensing a fluid pressure; comparing the fluid pressure to a threshold value, and if the fluid pressure is below the threshold value, then pausing fluid flow for a selected period. During the selected period, either the fluid pressure sensed automatically resolves or the method further comprises a step of setting a fall alarm condition. The method and apparatus may further include interpreting a particular quantity of below threshold fluid pressure occurrences where the fluid pressure is below the threshold value occurring within a particular time period, and then, signalling an alarm.
    Type: Application
    Filed: December 22, 2000
    Publication date: December 6, 2001
    Inventors: Marlene A. Bainbridge, Thomas J. Felt
  • Publication number: 20010000185
    Abstract: Improved extracorporeal blood processing methods and apparatus are disclosed. In one aspect of the invention, an extracorporeal method for the collection of platelets and red blood cells, and if desired plasma, is provided, wherein the collection of platelets and red blood cells may occur in differing time periods utilizing the same blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed and returned to a donor/patient during alternating blood removal and blood return submodes. Prior to red blood cell collection, a set-up phase may be carried out during which a predetermined hematocrit and AC ratio is established.
    Type: Application
    Filed: December 4, 2000
    Publication date: April 5, 2001
    Inventors: Muriel Keller, Marlene Bainbridge
  • Patent number: 6200287
    Abstract: Improved extracorporeal blood processing methods and apparatus are disclosed. In one aspect of the invention, an extracorporeal method for the collection of platelets and red blood cells, and if desired plasma, is provided, wherein the collection of platelets and red blood cells may occur in differing time periods utilizing the same blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed and returned to a donor/patient during alternating blood removal and blood return submodes. Prior to red blood cell collection, a set-up phase may be carried out during which a predetermined hematocrit and AC ratio is established.
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: March 13, 2001
    Assignee: Gambro, Inc.
    Inventors: Muriel Keller, Marlene Bainbridge
  • Patent number: 4824339
    Abstract: A peristaltic pump cartridge including a continuous flexible tube having two ends and a portion therebetween providing a U-shaped loop for use with a rotor and rollers to provide a peristaltic pump, a cartridge housing having supports for maintaining the portion of the flexible tube in the U-shaped loop external to the housing, the legs of the U-shaped loop leading into the housing, the housing having apertures through which connecting portions of the flexible tube remote from the U-shaped loop have been threaded from the interior to the exterior of the housing.
    Type: Grant
    Filed: August 19, 1987
    Date of Patent: April 25, 1989
    Assignee: Cobe Laboratories, Inc.
    Inventors: Marlene A. Bainbridge, Charles B. Powell, P. Michael Finsterwald