Patents by Inventor Marlene D. McElroy, deceased

Marlene D. McElroy, deceased has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinantly produced Coleoptera luciferase and fusion proteins thereof
    Patent number: 5700673
    Abstract: A method is disclosed for producing a protein which expresses bioluminescence activity which involves combining two polydeoxyribonucleotides, one containing a continuous sequence of codons encoding a polypeptide which comprises a single covalently bonded molecular structure and which catalyzes the oxidation of insect luciferin to yield light and the other which causes DNA transcription, and obtaining the polypeptide by transcription and subsequent translation. The insect luciferin is derived from bioluminescent insect, preferably Diptera and Coleoptera (fireflies and beetles). Hybrid proteins are similarly formed by inclusion of an additional polydeoxyribonucleotide encoding for a second polypeptide such that their respective polypeptide-encoding reading frames form a continuous reading frame.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: December 23, 1997
    Assignee: The Regents of the University of California
    Inventors: Marlene D. McElroy, deceased, Donald R. Helinski, Keith V. Wood, Jeffrey R. De Wet, David W. Ow, Stephen H. Howell
  • Recombinant expression of Coleoptera luciferase
    Patent number: 5583024
    Abstract: A method is disclosed for producing a protein which expresses bioluminescence activity which involves combining two polydeoxyribonucleotides, one containing a continuous sequence of codons encoding a polypeptide which comprises a single covalently bonded molecular structure and which catalyzes the oxidation of insect luciferin to yield light and the other which causes DNA transcription, and obtaining the polypeptide by transcription and subsequent translation. The insect luciferin is derived from bioluminescent insect, preferably Diptera and Coleoptera (fireflies and beetles). Hybrid proteins are similarly formed by inclusion of an additional polydeoxyribonucleotide encoding for a second polypeptide such that their respective polypeptide-encoding reading frames form a continuous reading frame.
    Type: Grant
    Filed: May 10, 1993
    Date of Patent: December 10, 1996
    Assignee: The Regents of the University of California
    Inventors: Marlene D. McElroy, deceased, W. D. McElroy, executor, Donald R. Helinski, Keith V. Wood, Jeffrey R. De Wet, David W. Ow, Stephen H. Howell