Patents by Inventor Marlene Espinoza Moraga

Marlene Espinoza Moraga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENANTIOSELECTIVE SYNTHESIS OF ASYMMETRIC BETA-CARBOLINE INTERMEDIATES
    Publication number: 20110245503
    Abstract: Described herein is a new asymmetric synthesis of imines to obtain ?-carboline derivatives useful as key intermediate compounds for the synthesis of phosphodiesterase inhibitors using a new process with palladium or ruthenium hydride and/or nickel boride to reduce chiral intermediates. The use of chloroformate chiral auxiliaries is further described for the reduction and asymmetric hydrogenation of imines to obtain ?-carboline derivatives and intermediate compounds used in the preparation thereof.
    Type: Application
    Filed: November 27, 2009
    Publication date: October 6, 2011
    Applicant: UNIVERSIDAD DE TALCA
    Inventors: Leonardo Santos, Marlene Espinoza Moraga, Nagula Shankarajah