Patents by Inventor Marlene Jacobson

Marlene Jacobson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for identifying cell surface receptor protein modulators
    Publication number: 20060275835
    Abstract: The present invention makes available a rapid, effective assay for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a target cell surface protein, e.g., a receptor or ion channel. The subject assay enables rapid screening of large numbers of compounds to identify those which modulate the bioactivity of the cellular proteins. The subject assays are particularly amenable for high throughput formats and are particular useful in identifying modulators of a mammalian metabotropic glutamate receptor protein.
    Type: Application
    Filed: July 9, 2004
    Publication date: December 7, 2006
    Inventors: Marlene Jacobson, Ruiping Wang
  • Treatment of psychosis with a muscarinic m1 receptor ectopic activator
    Publication number: 20060233843
    Abstract: A muscarinic M1 receptor ectopic activator, such as a muscarinic M1 receptor allosteric potentiator or a muscarinic M1 receptor ectopic agonist is useful, alone or in combination with other antipsychotic agents, for treating or preventing psychosis, such as a schizophrenic disorder or psychosis in Alzheimer's disease or bipolar disorder, for enhancing cognition and for neuropathic pain.
    Type: Application
    Filed: February 17, 2004
    Publication date: October 19, 2006
    Inventors: P. Conn, Marlene Jacobson, Pierre Mallorga, Edward Scolnick, Cyrille Sur