Patents by Inventor Marlieke Overdijk

Marlieke Overdijk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for amplifying nucleic acids
    Patent number: 9005896
    Abstract: The present invention describes methods for amplifying a target nucleic acid wherein target nucleic acids hybridize to capture probe nucleic acids which are immobilized to a support via their 5? end. The hybridization product is further extended with a polymerase to form a double stranded nucleic acid. To this double stranded nucleic acid, a hairpin nucleic acid is ligated. This ligation product is further amplified and sequenced.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: April 14, 2015
    Assignee: Koninklijke Philips N.V.
    Inventors: Harma Feitsma, Marlieke Overdijk, Anja Van De Stople, Pieter Jan Van Der Zaag
  • METHOD FOR AMPLIFYING NUCLEIC ACIDS
    Publication number: 20130210008
    Abstract: The present invention describes methods for amplifying a target nucleic acid wherein target nucleic acids hybridise to capture probe nucleic acids which are immobilized to a support via their 5? end. The hybridization product is further extended with a polymerase to form a double stranded nucleic acid. To this double stranded nucleic acid, a hairpin nucleic acid is ligated. This ligation product is further amplified and sequenced.
    Type: Application
    Filed: August 31, 2011
    Publication date: August 15, 2013
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Harma Feitsma, Marlieke Overdijk, Anja Van De Stople, Pieter Jan Van Der Zaag
  • Nucleic acid sequences that can be used as primers and probes in the amplification and detection of SARS coronavirus
    Patent number: 8106172
    Abstract: The present invention is related to nucleic acid sequences that can be used in the field of virus diagnostics, more specifically the diagnosis of infections with a novel human coronavirus causing Severe Acute Respiratory Syndrome (SARS). With the present invention nucleotide sequences are provided that can be used as primers and probes in the amplification and detection of SARS nucleic acid. The oligonucleotide sequences provided with the present invention are located in the replicase gene, the nucleocapsid gene and the 3? end non-coding region of the SARS Coronavirus genome. It has been found that, by using the sequences of the present invention in methods for the amplification and detection of nucleic acid a sensitive and specific detection of SARS Coronavirus can be obtained. The oligonucleotide sequences according to the present invention are especially useful in methods for the amplification of nucleic acid.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: January 31, 2012
    Assignee: Biomerieux, B.V.
    Inventors: Peter T. G. Sillekens, Marlieke Overdijk, Saskia van de Laar
  • Nucleic Acid Sequences That Can Be Used As Primers And Probes In The Amplification And Detection Of Sars Coronavirus
    Publication number: 20090226885
    Abstract: The present invention is related to nucleic acid sequences that can be used in the field of virus diagnostics, more specifically the diagnosis of infections with a novel human coronavirus causing Severe Acute Respiratory Syndrome (SARS). With the present invention nucleotide sequences are provided that can be used as primers and probes in the amplification and detection of SARS nucleic acid. The oligonucleotide sequences provided with the present invention are located in the replicase gene, the nucleocapsid gene and the 3? end non-coding region of the SARS Coronavirus genome. It has been found that, by using the sequences of the present invention in methods for the amplification and detection of nucleic acid a sensitive and specific detection of SARS Coronavirus can be obtained. The oligonucleotide sequences according to the present invention are especially useful in methods for the amplification of nucleic acid.
    Type: Application
    Filed: March 8, 2004
    Publication date: September 10, 2009
    Inventors: P.T.G Sillekens, Marlieke Overdijk, Saskia van de Laar