Abstract: Disclosed is a neurostimulation system comprising: a neuromodulation device for controllably delivering neural stimuli; a headset configured to be worn by the patient and to display images of a virtual object to the patient; one or more sensors configured to perceive a gesture of the patient; and an external computing device. The neuromodulation device comprises: a plurality of implantable electrodes; a stimulus source configured to deliver neural stimuli via selected ones of the implantable electrodes to a neural pathway of a patient; and a control unit configured to control the stimulus source to deliver each neural stimulus according to one or more stimulus parameters. The external computing device comprises a processor in communication with the neuromodulation device, the headset, and the one or more sensors.

Abstract: An implantable device comprising: stimulus electrodes and measurement electrodes; a stimulus source to provide a neural stimulus to be delivered to a neural pathway of a patient to evoke a neural response; measurement circuitry configured to capture a signal window sensed on the neural pathway; and a control unit configured to implement closed-loop neurostimulation therapy by: controlling the stimulus source to provide the neural stimulus according to a stimulus intensity parameter; measuring a characteristic of the signal window; computing a feedback variable from an intensity of an evoked neural response in the signal window; adjusting the stimulus intensity parameter using the feedback variable; and repeating the controlling, measuring, computing, and adjusting to maintain the feedback variable at a target, thereby obtaining multiple measured intensities of neural responses; and computing one or more quantitative indicators of efficacy of the closed-loop neurostimulation therapy using the measured characte

Abstract: Disclosed is a neuromodulation system comprising a neuromodulation device for controllably delivering a neural stimulus, and a processor.

Abstract: Disclosed is an implantable device for lead offset determination, comprising first and second electrode leads. A stimulus is delivered from one lead to tissue, and a signal is sensed from the tissue by the other lead. The sensed signal is processed to produce a measure of a stimulus artefact present in the signal. The stimulus artefact measure is used to produce a measure of an offset between the first electrode lead and the second electrode lead, such as by applying a distance-squared. analytical model to measures of stimulus artefact obtained from at least two sense electrodes. And/or, a compound action potential evoked by the stimulus is sensed from neural tissue, a latency of the evoked compound action potential is measured, and a measure of an offset between the first electrode lead and the second electrode lead is produced from the latency.

Abstract: Disclosed is a method of adapting the operation of an implantable device for delivering neurostimulation therapy to a patient. The method comprises: delivering the neurostimulation therapy to electrically excitable tissue of the patient according to at least one therapy parameter; measuring a physiological characteristic of the patient; adjusting the at least one therapy parameter according to a schedule of adjustment and the measured physiological characteristic; and repeating the delivering, measuring, and adjusting.

Abstract: An implantable device, or an associated computer program, for estimating a nerve conduction velocity. A stimulus is applied from one or more stimulus electrodes to a nerve. A digitised neural measurement of at least one compound action potential evoked by the at least one stimulus is obtained from one or more recording electrodes by measurement circuitry. The digitised neural measurement comprises a plurality of data sample points. The digitised neural measurement is processed in order to estimate within subsample precision a temporal position of a feature of interest of the compound action potential. From the estimated temporal position of the feature of interest, and from a propagation distance, a conduction velocity of the compound action potential is determined.

Abstract: A system and method for creating and for managing human resources over a decentralized human resources network is provided herein.

Abstract: A system for managing clinical data of an implanted neuromodulation device. An implanted neuromodulation device delivers electrical neurostimulation therapy, and captures recordings of neural responses to the electrical neurostimulation therapy. The device communicates clinical data including recordings of the neural responses to a non-implanted receiver. A supervisory device receives clinical data from the implanted neuromodulation device via the receiver, and presents the clinical data for review by a reviewer.

Abstract: A method for detecting cancer levels in a human patient by monitoring antigen levels in the blood stream of the patient. Polysilicon mirrors are administrated into the blood stream of the b patient orally or by injection. Near infrared light is transmitted through the patient's skin and reflected by the mirrors to a detector that converts the light to a readable signal for calculating the cancer level based on the level of antigen markers in the patients blood stream.

Abstract: A method for detecting cancer in a subject includes administering polysilicon mirrors to the subject, transmitting near infrared light through subject's skin, receiving light which is reflected from the polysilicon mirrors though the subject's skin, converting received light into a digital signal and calculating a level of CEA in the subject's blood from the digital signal.

Abstract: A method for detecting cancer in a subject includes administering polysilicon mirrors to the subject, transmitting near infrared light through subject's skin, receiving light which is reflected from the polysilicon mirrors though the subject's skin, converting received light into a digital signal and calculating a level of CEA in the subject's blood from the digital signal.