Patents by Inventor Marna Williams
Marna Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220403033Abstract: Methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases including ulcerative colitis and Crohn's disease are provided. Also provided are methods of administering integrin beta7 antagonists, such as anti-beta7 antibodies. In addition, particular dosing regimens, including dosing regimens comprising subcutaneous administration and administration using self-inject devices are provided.Type: ApplicationFiled: February 3, 2022Publication date: December 22, 2022Applicant: GENENTECH, INC.Inventors: Banmeet Anand, Eric Stefanich, Meina Tang, Jennifer Visich, Marna Williams, Sharon O'Byrne
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Publication number: 20210238288Abstract: Methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases including ulcerative colitis and Crohn's disease are provided. Also provided are methods of administering integrin beta7 antagonists, such as anti-beta7 antibodies. In addition, particular dosing regimens, including dosing regimens comprising subcutaneous administration and administration using self-inject devices are provided.Type: ApplicationFiled: February 4, 2020Publication date: August 5, 2021Applicant: GENENTECH, INC.Inventors: Banmeet Anand, Eric Stefanich, Meina Tang, Jennifer Visich, Marna Williams, Sharon O'Byrne
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Publication number: 20200031929Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: October 10, 2019Publication date: January 30, 2020Inventors: Marna WILLIAMS, J. Yun Tso, Nicholas F. Landolfi, Gao Liu
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Patent number: 10442859Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: September 22, 2015Date of Patent: October 15, 2019Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, Gao Liu
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Publication number: 20160002335Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: September 22, 2015Publication date: January 7, 2016Inventors: Marna WILLIAMS, J. Yun Tso, Nicholas F. Landolfi, Gao Liu
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Patent number: 9175081Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: May 15, 2013Date of Patent: November 3, 2015Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, Gao Liu
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Publication number: 20140120084Abstract: Methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases including ulcerative colitis and Crohn's disease are provided. Also provided are methods of administering integrin beta7 antagonists, such as anti-beta7 antibodies. In addition, particular dosing regimens, including dosing regimens comprising subcutaneous administration and administration using self-inject devices are provided.Type: ApplicationFiled: September 24, 2013Publication date: May 1, 2014Applicant: GENENTECH, INC.Inventors: Banmeet Anand, Eric Stefanich, Meina Tang, Jennifer Visich, Marna Williams, Sharon O'Byrne
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Publication number: 20140065063Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: May 15, 2013Publication date: March 6, 2014Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, Gao Liu
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Patent number: 8461306Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: July 1, 2011Date of Patent: June 11, 2013Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Patent number: 8444980Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: July 1, 2011Date of Patent: May 21, 2013Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Patent number: 8445646Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: June 30, 2011Date of Patent: May 21, 2013Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, Gao Liu
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Patent number: 8436146Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: July 1, 2011Date of Patent: May 7, 2013Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Patent number: 8349330Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: July 1, 2011Date of Patent: January 8, 2013Assignee: Abbott Biotherapeutics Corp.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Publication number: 20120070440Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: July 1, 2011Publication date: March 22, 2012Applicant: ABBOTT BIOTHERAPEUTICS CORP.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Publication number: 20120064068Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: July 1, 2011Publication date: March 15, 2012Applicant: Abbott Biotherapeutics Corp.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Publication number: 20120064067Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: July 1, 2011Publication date: March 15, 2012Applicant: ABBOTT BIOTHERAPEUTICS CORP.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Publication number: 20120064069Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: July 1, 2011Publication date: March 15, 2012Applicant: ABBOTT BIOTHERAPEUTICS CORP.Inventors: Marna WILLIAMS, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Llu
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Publication number: 20120064083Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: June 30, 2011Publication date: March 15, 2012Applicant: ABBOTT BIOTHERAPEUTICS CORP.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, Gao Liu
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Patent number: 8133981Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: March 10, 2009Date of Patent: March 13, 2012Assignee: Abbott Biotherapeutics Corp.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, Gao Liu
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Patent number: 8088898Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: March 3, 2009Date of Patent: January 3, 2012Assignee: Abbott Biotherapeutics Corp.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, Gao Liu