Patents by Inventor Marnix Peferoen

Marnix Peferoen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10858666
    Abstract: This disclosure relates to a transgenic plant or plant tissue or plant cell comprising at least one polynucleotide encoding a polypeptide comprising a variable domain of a heavy-chain antibody (VHH) specifically binding to a sphingolipid of a fungus. This disclosure further relates to a method for protecting at least part of a plant, plant tissue or plant cell from an infection with a plant pathogen, for inhibiting the growth of a plant pathogen on at least part of a plant, plant tissue or plant cell, or for increasing pathogen resistance of at least part of a plant, plant tissue or plant cell.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: December 8, 2020
    Assignee: BIOTALYS
    Inventors: Peter Verheesen, Jan Geerinck, João Filipe Veloso Vieira, Marnix Peferoen, Inge Elodie Van Daele
  • Publication number: 20180222966
    Abstract: This disclosure relates to a transgenic plant or plant tissue. In particular, this disclosure relates to a transgenic plant or plant tissue or plant cell comprising at least one polynucleotide comprising at least one sequence encoding a variable domain of a heavy-chain antibody (VHH) specifically binding to a sphingolipid of a fungus. Advantageously, the expression of the polynucleotide in at least part of the transgenic plant or plant tissue or plant cell (i) protects at least part of the transgenic plant or plant tissue or plant cell from an infection with a plant pathogenic fungus, (ii) inhibits the growth of a plant pathogenic fungus on at least part of the transgenic plant or plant tissue or plant cell, or (iii) increases the resistance of at least part of the transgenic plant or plant tissue or plant cell against a plant pathogenic fungus.
    Type: Application
    Filed: March 20, 2018
    Publication date: August 9, 2018
    Inventors: Peter Verheesen, Chris De Jonghe, Jan Geerinck, Inge Elodie Van Daele, Miguel Francesco Coleta De Bolle, João Filipe Veloso Vieira, Marnix Peferoen, Karin Thevissen, Bruno Cammue
  • Publication number: 20180179551
    Abstract: This disclosure relates to a transgenic plant or plant tissue. In particular this disclosure relates to a transgenic plant or plant tissue or plant cell comprising at least one polynucleotide comprising at least one sequence encoding a variable domain of a heavy-chain antibody (VHH) specifically binding to a sphingolipid of a fungus. Advantageously, the expression of the polynucleotide in at least part of the transgenic plant or plant tissue or plant cell (i) protects at least part of the transgenic plant or plant tissue or plant cell from an infection with a plant pathogenic fungus, (ii) inhibits the growth of a plant pathogenic fungus on at least part of the transgenic plant or plant tissue or plant cell, or (iii) increases the resistance of at least part of the transgenic plant or plant tissue or plant cell against a plant pathogenic fungus.
    Type: Application
    Filed: November 5, 2015
    Publication date: June 28, 2018
    Applicant: AGROSAVFE N.V.
    Inventors: Peter Verheesen, Jan Geerinck, João Filipe Veloso Vieira, Marnix Peferoen, Inge Elodie Van Daele
  • Patent number: 7888471
    Abstract: Four novel Bacillus thuringiensis strains, which are deposited at the BCCM-LMG under accession nos. LMG P-12592, LMG P-12593, LMG P-12594, and LMG P-13493, produce new crystal proteins during sporulation that are toxic to Lepidoptera, more particularly against Noctuidae such as Spodoptera spp. and Agrotis ipsilon, against Pyralidae such as Ostrinta nubilalis, and against Yponomeutidae such as Plutella xylostella, and that are encoded by a novel gene. The crystal proteins contain protoxins, which can yield a toxin as trypsin-digestion product. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that encodes its respective toxin, is resistant to Lepidoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Lepidoptera.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: February 15, 2011
    Assignee: Bayer Bioscience N.V.
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen
  • Publication number: 20090192290
    Abstract: Four novel Bacillus thuringiensis strains, which are deposited at the BCCM-LMG under accession nos. LMG P-12592, LMG P-12593, LMG P-12594, and LMG P-13493, produce new crystal proteins during sporulation that are toxic to Lepidoptera, more particularly against Noctuidae such as Spodoptera spp. and Agrotis ipsilon, against Pyralidae such as Ostrinta nubilalis, and against Yponomeutidae such as Plutella xylostella, and that are encoded by a novel gene. The crystal proteins contain protoxins, which can yield a toxin as trypsin-digestion product. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that encodes its respective toxin, is resistant to Lepidoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Lepidoptera.
    Type: Application
    Filed: March 14, 2008
    Publication date: July 30, 2009
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen
  • Patent number: 7361751
    Abstract: Four novel Bacillus thuringiensis strains, which are deposited at the BCCM-LMG under accession nos. LMG P-12592, LMG P-12593, LMG P-12594, and LMG P-13493, produce new crystal proteins during sporulation that are toxic to Lepidoptera, more particularly against Noctuidae such as Spodoptera spp. and Agrotis ipsilon, against Pyralidae such as Ostrinta nubilalis, and against Yponomeutidae such as Plutella xylostella, and that are encoded by a novel gene. The crystal proteins contain protoxins, which can yield a toxin as trypsin-digestion product. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that encodes its respective toxin, is resistant to Lepidoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Lepidoptera.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: April 22, 2008
    Assignee: Bayer Bioscience N.V.
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen
  • Publication number: 20050097635
    Abstract: Four novel Bacillus thuringiensis strains, which are deposited at the BCCM-LMG under accession nos. LMG P-12592, LMG P-12593, LMG P-12594, and LMG P-13493, produce new crystal proteins during sporulation that are toxic to Lepidoptera, more particularly against Noctuidae such as Spodoptera spp. and Agrotis ipsilon, against Pyralidae such as Ostrinta nubilalis, and against Yponomeutidae such as Plutella xylostella, and that are encoded by a novel gene. The crystal proteins contain protoxins, which can yield a toxin as trypsin-digestion product. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that encodes its respective toxin, is resistant to Lepidoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Lepidoptera.
    Type: Application
    Filed: October 20, 2003
    Publication date: May 5, 2005
    Applicant: BAYER BIOSCIENCE N.V.
    Inventors: Bart Lambert, Stefan Jansens, Katrien Audenhove, Marnix Peferoen
  • Patent number: 6727409
    Abstract: Four novel Bacillus thuringiensis strains, which are deposited at the BCCM-LMG under accession nos. LMG P-12592, LMG P-12593, LMG P-12594, and LMG P-13493, produce new crystal proteins during sporulation that are toxic to Lepidoptera, more particularly against Noctuidae such as Spodoptera spp. and Agrotis ipsilon, against Pyralidae such as Ostrinta nubilalis, and against Yponomeutidae such as Plutella xylostella, and that are encoded by a novel gene. The crystal proteins contain protoxins, which can yield a toxin as trypsin-digestion product. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that encodes its respective toxin, is resistant to Lepidoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Lepidoptera.
    Type: Grant
    Filed: December 28, 1998
    Date of Patent: April 27, 2004
    Assignee: Bayer BioScience N.V.
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen
  • Patent number: 6448226
    Abstract: The present invention relates to transformed plants and plant cells comprising DNA molecules encoding Bacillus thuringiensis proteins with insecticidal activity. The invention relates more particularly to transformed plants and plant cells comprising DNA molecules encoding the protease resistant toxins BTS02618Aa or BTS02618Ab, as well as to methods of rendering plants or plant cells resistant to insects using these DNA molecules.
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: September 10, 2002
    Assignee: Aventis CropScience N.V.
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen, Jeroen Van Rie, Roel Van Aarssen
  • Patent number: 6143550
    Abstract: The present invention relates to transformed microrganisms comprising DNA molecules encoding Bacillus thuringiensis proteins with insecticidal activity. The invention relates more particularly to transformed microrganisms comprising DNA molecules encoding the protease resistant toxins BTS02618Aa or BTS02618Ab.
    Type: Grant
    Filed: February 6, 1998
    Date of Patent: November 7, 2000
    Assignee: Aventis CropScience
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen, Jeroen Van Rie, Roel Van Aarssen
  • Patent number: 6028246
    Abstract: Four novel Bacillus thuringiensis strains, which are deposited at the BCCM-LMG under accession nos. LMG P-12592, LMG P-12593, LMG P-12594, and LMG P-13493, produce new crystal proteins during sporulation that are toxic to Lepidoptera, more particularly against Noctuidae such as spodoptera spp. and Agotis ipsilon, against Pyralidae such as Ostrinia nubilalis, and against Yponomeutidae such as Plutella xylostella, and that are encoded by a novel gene. The crystal proteins contain protoxins, which can yield a toxin as trypsin-digestion product. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains nd that encodes its respective toxin, is resistant to Lipidoptera. Each strain, itself, or its crystal, crystal protein, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combating Lepidoptera.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: February 22, 2000
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen
  • Patent number: 5885571
    Abstract: Four novel Bacillus thurungienisis strains which are deposited at the BCCM-LMG under accesion nos. LMG P-12592, LMG P-12593, LMG P-12594, and LMG P-13493, produce new crystal proteins during sporulation that are toxic to Lepidoptera, more particularly against Noctuidae such as Spodoptera spp. and Agrotis ipsilon, against Pyralidae such as Ostrinia nubilalis, and against Yponomeutidae such as Plutella xylostella, and that are encoded by a novel gene. The crystal proteins contain protoxins, which can yield a toxin as trypsin-digestion product. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that encodes its respective toxin, is resistant to Lepidoptera. Each strain, itself, or its crystals, crystals proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Lepidoptera.
    Type: Grant
    Filed: March 23, 1995
    Date of Patent: March 23, 1999
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen
  • Patent number: 5861543
    Abstract: The present invention relates to transformed plants and plant cells comprising DNA molecules encoding Bacillus thuringiensis proteins with insecticidal activity. The invention relates more particularly to transformed plants and plant cells comprising DNA molecules encoding the protease resistant toxins BTS02618Aa or BTS02618Ab, as well as to methods of rendering plants or plant cells resistant to insects using these DNA molecules.
    Type: Grant
    Filed: December 6, 1995
    Date of Patent: January 19, 1999
    Assignee: Plant Genetic Systems N.V.
    Inventors: Bart Lambert, Stefan Jansens, Katrien Van Audenhove, Marnix Peferoen, Jeroen Van Rie, Roel Van Aarssen
  • Patent number: 5837237
    Abstract: Two new Bacillus thuringiensis strains, which are deposited at the DSM under accession numbers 5870 and 5871, produce new crystal proteins during sporulation that are toxic to Coleoptera and that are encoded by new genes. The crystal proteins contain protoxins, which can yield toxins as trypsin-digestion products. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and encodes an insecticidally effective portion of its respective protoxin or encodes its respective toxin, is resistant to Coleoptera. Each strain, itself, or its crystals, crystal proteins, protoxin, toxin and/or insecticidally effective protoxin portion can be used as the active ingredient in an insecticidal composition for combatting Coleoptera.
    Type: Grant
    Filed: January 29, 1997
    Date of Patent: November 17, 1998
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Marnix Peferoen, Bart Lambert, Katrien Van Audenhove
  • Patent number: 5723756
    Abstract: Two new Bacillus thuringiensis strains, which are deposited at the DSM under accession numbers 5870 and 5871, produce new crystal proteins during sporulation that are toxic to Coleoptera and that are encoded by new genes. The crystal proteins contain protoxins, which can yield toxins as trypsin-digestion products. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and encodes an insecticidally effective portion of its respective protoxin or encodes its respective toxin, is resistant to Coleoptera. Each strain, itself, or its crystals, crystal proteins, protoxin, toxin and/or insecticidally effective protoxin portion can be used as the active ingredient in an insecticidal composition for combatting Coleoptera.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: March 3, 1998
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Marnix Peferoen, Bart Lambert, Katrien Van Audenhove
  • Patent number: 5683691
    Abstract: Two new Bacillus thuringiensis strains, which are deposited at the DSM under accession nos. 5131 and 5132, produce crystal proteins during sporulation that are toxic to Coleoptera. The crystal proteins contain 74 kDa and 129 kDa protoxins, respectively, which can yield 68 and 66 kDa toxins, respectively, as trypsin-digestion products. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that codes for its respective toxin, is resistant to Coleoptera. Each strain, itself, or its crystals, crystal proteins, protoxin or toxin can be used as the active ingredient in an insecticidal composition for combatting Coleoptera.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: November 4, 1997
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Marnix Peferoen, Bart Lambert, Henk Joos
  • Patent number: 5659123
    Abstract: New modified Cry proteins, particularly modified CryIIIA proteins, having significantly altered toxicity, and DNA sequences encoding these proteins, are designed. Analysis of solvent-accessible amino acid positions in domain II of the CryIIIA protein by alanine-scanning mutagenesis identified individual amino acids involved in corn rootworm toxicity. Random replacement of these amino acids identifies modified proteins with improved toxicity. A combination of all or most thus identified improved amino acids in a single protein yields modified CryIIIA proteins with significantly improved toxicity. Particularly regions protruding from the Cry molecule and located at the apex of the Cry proteins, were identified as involved in toxicity.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: August 19, 1997
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Jeroen Van Rie, Stefan Jansens, Marnix Peferoen
  • Patent number: 5628995
    Abstract: A method to combat or control Ostrinia nubilalis by contacting such insects with a CryIB protein or a combination of a CryIB protein and a CryIAb or CryIAc protein.
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: May 13, 1997
    Assignee: Plant Genetic Systems N.V.
    Inventors: Marnix Peferoen, Stefan Jansens, Peter Denolf
  • Patent number: 5530197
    Abstract: A method to combat or control Ostrinia nubilalis by contacting such insects with a CryIB protein or a combination of a CryIB protein and a CryIAb or CryIAc protein.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 25, 1996
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Marnix Peferoen, Stefan Jansens, Peter Denolf
  • Patent number: 5466597
    Abstract: Two new Bacillus thuringiensis strains, which are deposited at the DSM under accession nos 5870 and 5871, produce new crystal proteins during sporulation that are toxic to Coleoptera and that are encoded by new genes. The crystal proteins contain protoxins, which can yield toxins as trypsin-digestion products. A plant, the genome of which is transformed with a DNA sequence that comes from either one of the strains and that encodes an insecticidally effective portion of its respective protoxin or encodes its respective toxin, is resistant to Coleoptera. Each strain, itself, or its crystals, crystal proteins, protoxin, toxin and/or insecticidally effective protoxin portion can be used as the active ingredient in an insecticidal composition for combating Coleoptera.
    Type: Grant
    Filed: November 17, 1992
    Date of Patent: November 14, 1995
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Marnix Peferoen, Bart Lambert, Katrien Van Audenhove