Abstract: A therapeutic effect assessment system, including: a probe shaped and sized to be inserted into a brain of a subject, having a proximal end and a distal end and a longitudinal axis, the probe including a plurality of contacts operably coupled thereto, disposed along the longitudinal axis, wherein the probe is selectively operable for stimulating an electrophysiological evoked responses; at least one electrode configured to record readings of evoked responses caused by the stimulating; and an analysis module electrically connected to the probe and to the at least one electrode, wherein the analysis module is configured to transform or reduce certain parameters from the recorded readings of evoked responses in order to identify a threshold of brain stimulation that produces a therapeutic effect.

Abstract: An electrode lead is provided having a distal side and a circumferential surface, the electrode lead comprising a plurality of interlocked filaments having a conductive core coated with a nonconductive coating and at least one 3D distinct conductive mass at the distal end, wherein the filaments in the conductive mass are having an exposed conductive core and wherein a portion of the filaments with the exposed conductive core are disposed on the circumferential surface. The 3d pattern of spaced-apart regions along or within the electrode lead, each one is a network of spaced-apart conductive segments determining together critical parameters of: directionality of the region and electrical property of the region.

Abstract: The present invention provides interlocked thread electrode leads, methods of fabrication thereof, and thread interlocking machines.

Abstract: The present invention provides interlocked thread electrode leads, methods of fabrication thereof, and thread interlocking machines.

Abstract: A kit including a medical guide template, and a sterilizable receptacle accommodating the guide template, the kit being configured to allow deformation of the template into an operational medical guide.

Abstract: A kit including a medical guide template, and a sterilizable receptacle accommodating the guide template, the kit being configured to allow deformation of the template into an operational medical guide.

Abstract: An electrode lead is provided having a distal side and a circumferential surface, the electrode lead comprising a plurality of interlocked filaments having a conductive core coated with a nonconductive coating and at least one 3D distinct conductive mass at the distal end, wherein the filaments in the conductive mass are having an exposed conductive core and wherein a portion of the filaments with the exposed conductive core are disposed on the circumferential surface. The 3d pattern of spaced-apart regions along or within the electrode lead, each one is a network of spaced-apart conductive segments determining together critical parameters of: directionality of the region and electrical property of the region.

Abstract: An electrode lead is provided having a distal side and a circumferential surface, the electrode lead comprising a plurality of interlocked filaments having a conductive core coated with a nonconductive coating and at least one 3D distinct conductive mass at the distal end, wherein the filaments in the conductive mass are having an exposed conductive core and wherein a portion of the filaments with the exposed conductive core are disposed on the circumferential surface. The 3d pattern of spaced-apart regions along or within the electrode lead, each one is a network of spaced-apart conductive segments determining together critical parameters of: directionality of the region and electrical property of the region.

Abstract: The disclosure relates to a surgical cranial drape, probe for mapping brain of a subject and their methods of use. Specifically, the disclosure relates to a sterile surgical cranial drape embedded with electrodes; an system for mapping physiologically functional brain regions using evoked electrophysiological responses in a first and a second region; and their methods of use in combination or separately.

Abstract: The disclosure relates to methods, systems and devices for positioning a stereotactic frame within a desired surgical site, and more particularly to stereotactic systems and methods of co-registration of stereotactic frames with imbedded fiducial markers.

Abstract: The disclosure relates to a surgical cranial drape, probe for mapping brain of a subject and their methods of use. Specifically, the disclosure relates to a sterile surgical cranial drape embedded with electrodes; an system for mapping physiologically functional brain regions using evoked electrophysiological responses in a first and a second region; and their methods of use in combination or separately.

Abstract: The present invention provides interlocked thread electrode leads, methods of fabrication thereof, and thread interlocking machines.

Abstract: An electrode lead is provided having a distal side and a circumferential surface, the electrode lead comprising a plurality of interlocked filaments having a conductive core coated with a nonconductive coating and at least one 3D distinct conductive mass at the distal end, wherein the filaments in the conductive mass are having an exposed conductive core and wherein a portion of the filaments with the exposed conductive core are disposed on the circumferential surface. The 3d pattern of spaced-apart regions along or within the electrode lead, each one is a network of spaced-apart conductive segments determining together critical parameters of: directionality of the region and electrical property of the region.

Abstract: A kit including a medical guide template, and a sterilizable receptacle accommodating the guide template, the kit being configured to allow deformation of the template into an operational medical guide.

Abstract: The disclosure relates to methods, systems and devices for positioning a stereotactic frame within a desired surgical site, and more particularly to stereotactic systems and methods of co-registration of stereotactic frames with imbedded fiducial markers.

Abstract: The disclosure relates to a surgical cranial drape, probe for mapping brain of a subject and their methods of use. Specifically, the disclosure relates to a sterile surgical cranial drape embedded with electrodes; an system for mapping physiologically functional brain regions using evoked electrophysiological responses in a first and a second region; and their methods of use in combination or separately.

Abstract: A multi-contact electrode for neural tissue stimulation is described. The electrode has an axis and includes a plurality of electrodes going along the axis. Each electrode ends with a contact, and at least one of the contacts has an internal edge, resulting in non-uniform electrical properties throughout the contact surface facing the tissue. Also described are methods of making an electrical contact with an internal edge, and methods and systems for characterizing internal edge.

Abstract: A multi-contact electrode for neural tissue stimulation is described. The electrode has an axis and includes a plurality of electrodes going along the axis. Each electrode ends with a contact, and at least one of the contacts has an internal edge, resulting in non-uniform electrical properties throughout the contact surface facing the tissue. Also described are methods of making an electrical contact with an internal edge, and methods and systems for characterizing internal edge.