Patents by Inventor Marshall Clark

Marshall Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11872236
    Abstract: Methods of treating presbyopia or cataract in a subject in need thereof are provided. The methods require administering to the subject an effective amount of a composition comprising a compound that inhibits the formation of high molecular weight aggregates of human ?-A-crystallin. Compositions containing certain compounds are believed to be also effective in the treatment of transthyretin (TTR)-associated amyloidosis and Parkinson's disease.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: January 16, 2024
    Assignee: CALASIA PHARMACEUTICALS, INC.
    Inventors: Surya Kanta De, Sridhar G. Prasad, Marshall Clarke Peterman, Bernard Collins
  • Publication number: 20220241247
    Abstract: Methods of treating presbyopia or cataract in a subject in need thereof are provided. The methods require administering to the subject an effective amount of a composition comprising a compound that inhibits the formation of high molecular weight aggregates of human ?-A-crystallin. A method of preventing and/or treating transthyretin (TTR)-associated amyloidosis using certain of these compounds is also provided.
    Type: Application
    Filed: June 1, 2020
    Publication date: August 4, 2022
    Inventors: Sridhar Govinda PRASAD, Marshall Clarke PETERMAN, Santosh SINHA
  • Publication number: 20210154213
    Abstract: Methods of treating presbyopia or cataract in a subject in need thereof are provided. The methods require administering to the subject an effective amount of a composition comprising a compound that inhibits the formation of high molecular weight aggregates of human ?-A-crystallin. Compositions containing certain compounds are believed to be also effective in the treatment of transthyretin (TTR)-associated amyloidosis and Parkinson's disease.
    Type: Application
    Filed: April 5, 2019
    Publication date: May 27, 2021
    Inventors: Surya Kanta DE, Sridhar G. PRASAD, Marshall Clarke PETERMAN, Bernard COLLINS
  • Patent number: 7816122
    Abstract: Devices, methods and kits for conducting an assay to determine the presence or amount of an analyte in a fluid sample. The device includes a sample application element and a flow path matrix that facilitates fluidic flow by capillary action. The sample application element includes a non-absorbent or absorbent carrier that has a conjugate reagent that is readily solubilized by the liquid sample. In various aspects of the invention, the sample application element and the matrix are associated with a housing that allows for releasable contact between the element and the matrix. In other aspects, the invention includes methods using the device and kits including the device.
    Type: Grant
    Filed: October 18, 2005
    Date of Patent: October 19, 2010
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Scott Marshall Clark, Keith Alan Nassif
  • Patent number: 7582472
    Abstract: There is provided a device for partitioning a liquefied sample into discrete volumes. The device includes a bottom member; a top member disposed adjacent the bottom member; and at least one channel member disposed between the top and bottom members. The at least one channel member is at least partially defined by the top and bottom members and has first and second end portions. The first end portion of the at least one channel has an opening to receive liquid and the second end portion of the at least one channel has a reaction compartment and a vent opening. Accordingly, when the liquefied sample is introduced to the first end portion, capillary action assists in causing the liquefied sample to travel from the first end portion to the second end portion and at least a portion of the liquefied sample is caused to remain in the reaction compartment.
    Type: Grant
    Filed: July 26, 2004
    Date of Patent: September 1, 2009
    Inventors: Kenneth E. Smith, Haoyi Gu, Scott William Wagner, Scott Marshall Clark, Chun-Ming Chen
  • Patent number: 7442557
    Abstract: A device for conducting an assay to determine the presence or amount of an analyte in a fluid sample. The device includes a flow path that facilitates fluidic flow by capillary action. The flow path has a first fluid permeable region, a second fluid permeable region, a barrier that inhibits fluidic flow between the first and second regions, and a fluidic bridge. The bridge includes a fluid permeable material overlapping at least a portion of each of the first region, the barrier and the second region.
    Type: Grant
    Filed: October 22, 2004
    Date of Patent: October 28, 2008
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Scott Marshall Clark, Michael Raymond Kepron
  • Patent number: 6393503
    Abstract: A parallel, fault-tolerant computer system in which data is transferred between processes in a single CPU by two methods. In a first method, the data is copied each time it is transferred. In a second method, the data is not copied, but is passed through a shared memory, queueing system. The first method is used to ensure fault-tolerance and linear expandability. The second method is used to minimize the time required for inter-process communication. Use of the shared memory queueing system allows for faster communication between processes executing in a same CPU.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: May 21, 2002
    Assignee: Compaq Computer Corporation
    Inventors: Leonard Richard Fishler, Thomas Marshall Clark
  • Patent number: 6032267
    Abstract: A parallel, fault-tolerant computer system in which data is transferred between processes in a single CPU by two methods. In a first method, the data is copied each time it is transferred. In a second method, the data is not copied, but is passed through a shared memory, queueing system. The first method is used to ensure fault-tolerance and linear expandability. The second method is used to minimize the time required for inter-process communication. Use of the shared memory queueing system allows for increased vertical and horizontal modularity for processes executing in a same CPU.
    Type: Grant
    Filed: August 14, 1997
    Date of Patent: February 29, 2000
    Assignee: Compaq Computer Corporation
    Inventors: Leonard Richard Fishler, Thomas Marshall Clark
  • Patent number: D268436
    Type: Grant
    Filed: January 28, 1980
    Date of Patent: March 29, 1983
    Inventor: Marshall Clark