Patents by Inventor Marshall L. Stoller

Marshall L. Stoller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11844724
    Abstract: A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: December 19, 2023
    Assignees: California Institute of Technology, The Regents of the University of California, United States Government represented by the Department of Veterans Affairs
    Inventors: Robert H. Grubbs, Marshall L Stoller, Ying Han, Frank L. Brodie
  • Publication number: 20230285561
    Abstract: This invention related to manufactured microbubbles, as well as methods of using manufactured microbubbles, for example, in medicinal applications. The invention pertains to the physical structure and materials of the microbubbles, as well as to methods for manufacturing microbubbles, methods for targeting microbubbles for specific medicinal applications, and methods for delivering microbubbles in medical treatment.
    Type: Application
    Filed: March 22, 2023
    Publication date: September 14, 2023
    Inventors: Robert H. GRUBBS, Marshall L. STOLLER, Hoyong CHUNG, Alissa M. FITZGERALD, Thomas W. KENNY, Renee M. THOMAS
  • Patent number: 11642410
    Abstract: This invention related to manufactured microbubbles, as well as methods of using manufactured microbubbles, for example, in medicinal applications. The invention pertains to the physical structure and materials of the microbubbles, as well as to methods for manufacturing microbubbles, methods for targeting microbubbles for specific medicinal applications, and methods for delivering microbubbles in medical treatment.
    Type: Grant
    Filed: December 7, 2021
    Date of Patent: May 9, 2023
    Assignees: California Institute of Technology, The Regents of the University of California
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Hoyong Chung, Alissa M. Fitzgerald, Thomas W. Kenny, Renee M. Thomas
  • Publication number: 20220088198
    Abstract: This invention related to manufactured microbubbles, as well as methods of using manufactured microbubbles, for example, in medicinal applications. The invention pertains to the physical structure and materials of the microbubbles, as well as to methods for manufacturing microbubbles, methods for targeting microbubbles for specific medicinal applications, and methods for delivering microbubbles in medical treatment.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 24, 2022
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Hoyong Chung, Alissa M. Fitzgerald, Thomas W. Kenny, Renee M. Thomas
  • Publication number: 20220087897
    Abstract: The disclosure pertains to methods and devices for administering a vibration expulsion therapy (VET) to a subject to expulse a urinary stone. The method comprises circumferentially administering vibrations to a subject's torso to facilitate movement of a urinary stone through the urinary system or to alleviate pain associated with a urinary stone. In certain embodiments, the method comprises circumferentially administering vibrations to a subject via a vest configured to envelope and tightly fit contours on the subject's torso, particular, the subject's lower torso and cover the subject's kidneys, ureter, and/or urinary bladder. Further provided is a system comprising a processor and a computer-readable medium comprising instructions that, when executed by the processor, causes the processor to actuate a vest placed on the subject's torso to circumferentially administer vibrations to the subject's torso or a portion thereof.
    Type: Application
    Filed: August 27, 2021
    Publication date: March 24, 2022
    Inventors: Marshall L. Stoller, Avi Baskin, David Bayne, Ralph Wang
  • Publication number: 20220040000
    Abstract: A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification.
    Type: Application
    Filed: October 25, 2021
    Publication date: February 10, 2022
    Applicants: California Institute of Technology, The Regents of the University of California, United States Government represented by the Department of Veterans Affairs
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Ying Han, Frank L. Brodie
  • Patent number: 11166846
    Abstract: A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification.
    Type: Grant
    Filed: January 3, 2020
    Date of Patent: November 9, 2021
    Assignees: California Institute of Technology, The Regents of the University of California, United States Government represented by the Department of Veterans Affairs
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Ying Han, Frank L. Brodie
  • Publication number: 20200214890
    Abstract: A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification.
    Type: Application
    Filed: January 3, 2020
    Publication date: July 9, 2020
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Ying Han, Frank L. Brodie
  • Patent number: 10357565
    Abstract: This invention related to manufactured microbubbles, as well as methods of using manufactured microbubbles, for example, in medicinal applications. The invention pertains to the physical structure and materials of the microbubbles, as well as to methods for manufacturing microbubbles, methods for targeting microbubbles for specific medicinal applications, and methods for delivering microbubbles in medical treatment.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: July 23, 2019
    Assignees: California Institute of Technology, The Regents of the University of California
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Hoyong Chung, Alissa M. Fitzgerald, Thomas W. Kenny, Renee M. Thomas
  • Patent number: 10258645
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: April 16, 2019
    Assignees: New York University, General Hospital Corporation, The Regents of the University of California
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Publication number: 20190038749
    Abstract: This invention related to manufactured microbubbles, as well as methods of using manufactured microbubbles, for example, in medicinal applications. The invention pertains to the physical structure and materials of the microbubbles, as well as to methods for manufacturing microbubbles, methods for targeting microbubbles for specific medicinal applications, and methods for delivering microbubbles in medical treatment.
    Type: Application
    Filed: October 8, 2018
    Publication date: February 7, 2019
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Hoyong Chung, Alissa M. Fitzgerald, Thomas W. Kenny, Renee M. Thomas
  • Patent number: 10149906
    Abstract: This invention related to manufactured microbubbles, as well as methods of using manufactured microbubbles, for example, in medicinal applications. The invention pertains to the physical structure and materials of the microbubbles, as well as to methods for manufacturing microbubbles, methods for targeting microbubbles for specific medicinal applications, and methods for delivering microbubbles in medical treatment.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: December 11, 2018
    Assignees: California Institute of Technology, The Regents of the University of California
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Hoyong Chung, Alissa M. Fitzgerald, Thomas W. Kenny, Renee M. Thomas
  • Patent number: 10052305
    Abstract: In various embodiments methods and composition are provided for the treatment and/or prophylaxis of cystinuria. In certain embodiments the methods involve administering to a mammal in need thereof (e.g., identified as at risk for, or having cystinuria) an effective amount of lipoic acid and/or one or more lipoic acid derivatives.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: August 21, 2018
    Assignee: BUCK INSTITUTE FOR RESEARCH ON AGING
    Inventors: Tiffany Zee, Marshall L. Stoller, Pankaj Kapahi
  • Publication number: 20180169144
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Application
    Filed: February 15, 2018
    Publication date: June 21, 2018
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Patent number: 9895396
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: February 20, 2018
    Assignees: New York University, General Hospital Corporation, The Regents of the University of California
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Publication number: 20170340664
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Application
    Filed: August 21, 2017
    Publication date: November 30, 2017
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Patent number: 9737564
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: August 22, 2017
    Assignees: New York University, General Hospital Corporation, The Regents of the University of California
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Publication number: 20170112804
    Abstract: In various embodiments methods and composition are provided for the treatment and/or prophylaxis of cystinuria. In certain embodiments the methods involve administering to a mammal in need thereof (e.g., identified as at risk for, or having cystinuria) an effective amount of lipoic acid and/or one or more lipoic acid derivatives.
    Type: Application
    Filed: October 3, 2016
    Publication date: April 27, 2017
    Inventors: TIFFANY ZEE, MARSHALL L. STOLLER, PANKAJ KAPAHI
  • Publication number: 20160367669
    Abstract: This invention related to manufactured microbubbles, as well as methods of using manufactured microbubbles, for example, in medicinal applications. The invention pertains to the physical structure and materials of the microbubbles, as well as to methods for manufacturing microbubbles, methods for targeting microbubbles for specific medicinal applications, and methods for delivering microbubbles in medical treatment.
    Type: Application
    Filed: June 30, 2016
    Publication date: December 22, 2016
    Inventors: Robert H. Grubbs, Marshall L. Stoller, Hoyong Chung, Alissa M. Fitzgerald, Thomas W. Kenny, Renee M. Thomas
  • Publication number: 20160184349
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Application
    Filed: March 7, 2016
    Publication date: June 30, 2016
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller