Patents by Inventor Marshall Levesque

Marshall Levesque has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting mutations in single cells or single molecules
    Patent number: 10752954
    Abstract: The invention provides a high efficiency fluorescence in situ hybridization (FISH) method for detecting mutations on individual RNA transcripts, including both exonic and intronic RNA transcripts. In certain embodiments, the method is used to quantify allelic expression at the population and single cell level, and also to distinguish maternal chromosomes from paternal chromosomes in single cells.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 25, 2020
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Arjun Raj, Marshall Levesque
  • METHOD FOR DETECTING MUTATIONS IN SINGLE CELLS OR SINGLE MOLECULES
    Publication number: 20160046999
    Abstract: The invention provides a high efficiency fluorescence in situ hybridization (FISH) method for detecting mutations on individual RNA transcripts, including both exonic and intronic RNA transcripts. In certain embodiments, the method is used to quantify allelic expression at the population and single cell level, and also to distinguish maternal chromosomes from paternal chromosomes in single cells.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 18, 2016
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Arjun Raj, Marshall Levesque