Patents by Inventor Marshall S. Scicchitano

Marshall S. Scicchitano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay to identify estrogen receptor dependent ligands that regulate the hepatic lipase promoter
    Patent number: 7521199
    Abstract: The present invention relates to an assay system and method for testing compounds for their ability to regulate the hepatic lipase (HL) promoter. In particular, the invention relates to the identification of estrogen receptor ligands having this activity. Compounds that inhibit HL promoter activity are useful as leads, or on their own, to develop therapeutics in the prevention of heart disease.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: April 21, 2009
    Assignee: Wyeth
    Inventors: Douglas C. Harnish, Marshall S. Scicchitano, Sotirios K. Karathanasis, Chu-Lai Hsiao
  • Member of the lysyl oxidase gene family
    Patent number: 7445920
    Abstract: The present invention relates to a novel lysyl oxidase genes, termed EER-7. The invention relates to the protein and nucleic acids encoding the protein. The invention further relates to an assay system to identify compounds that selectively modulate EER-7 protein activity by interaction with estrogen receptors.
    Type: Grant
    Filed: June 6, 2003
    Date of Patent: November 4, 2008
    Assignee: Wyeth
    Inventors: Mark J. Evans, Marshall S. Scicchitano, Ashok R. Bapat, Ramesh A. Bhat, Robert Mastroeni, Sotirios K. Karathanasis
  • Member of the lysyl oxidase gene family
    Patent number: 7208300
    Abstract: The present invention relates to a novel lysyl oxidase genes, termed EER-7. The invention relates to the protein and nucleic acids encoding the protein. The invention further relates to an assay system to identify compounds that selectively modulate EER-7 protein activity by interaction with estrogen receptors.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: April 24, 2007
    Assignee: Wyeth
    Inventors: Mark J. Evans, Marshall S. Scicchitano, Ashok R. Bapat, Ramesh A. Bhat, Robert Mastroeni, Sotirios K. Karathanasis
  • Assay to identify estrogen receptor dependent ligands that regulate the hepatic lipase promoter
    Patent number: 7094559
    Abstract: The present invention relates to an assay system and method for testing compounds for their ability to regulate the hepatic lipase (HL) promoter. In particular, the invention relates to the identification of estrogen receptor ligands having this activity. Compounds that inhibit HL promoter activity are useful as leads, or on their own, to develop therapeutics in the prevention of heart disease.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: August 22, 2006
    Assignee: Wyeth
    Inventors: Douglas C. Harnish, Marshall S. Scicchitano, Sotirios K. Karathanasis, Chu-Lai Hsiao
  • Novel member of the lysyl oxidase gene family
    Publication number: 20040171110
    Abstract: The present invention relates to a novel lysyl oxidase genes, termed EER-7. The invention relates to the protein and nucleic acids encoding the protein. The invention further relates to an assay system to identify compounds that selectively modulate EER-7 protein activity by interaction with estrogen receptors.
    Type: Application
    Filed: June 6, 2003
    Publication date: September 2, 2004
    Applicant: Wyeth
    Inventors: Mark J. Evans, Marshall S. Scicchitano, Ashok R. Bapat, Eric Beer, Ramesh A. Bhat, Elissa Ferris, Robert Mastroeni, Jianxiong Zhang, Sotirios K. Karathanasis
  • Novel member of the lysyl oxidase gene family
    Publication number: 20020102645
    Abstract: The present invention relates to a novel lysyl oxidase genes, termed EER-7. The invention relates to the protein and nucleic acids encoding the protein. The invention further relates to an assay system to identify compounds that selectively modulate EER-7 protein activity by interaction with estrogen receptors.
    Type: Application
    Filed: August 8, 2001
    Publication date: August 1, 2002
    Applicant: American Home Products Corporation
    Inventors: Mark J. Evans, Marshall S. Scicchitano, Ashok R. Bapat, Eric Beer, Ramesh A. Bhat, Elissa Ferris, Robert Mastroeni, Jianxiong Zhang, Sotirios K. Karathanasis