Patents by Inventor Marta Dueñas Porto

Marta Dueñas Porto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies and Fv fragment recognizing antigen IOR C2
    Patent number: 6891023
    Abstract: Novel recombinant antibodies from murine antibody IOR C5 produced by the hybridoma deposited with the ECCC 97061101. The recombinant antibodies were obtained using recombinant DNA technology and are characterized in that they recognize antigen ior C2. The recombinant antibodies are specifically chimeric antibody, humanized antibody, and single chain Fv fragment. The chimeric antibody contains the variable domains of the murine immunoglobuline and the constant regions of the human immunoglobuline. The humanized antibody contains the constant regions of human immunoglobuline and has been specifically modified in the murine frameworks regions (FRs) and within the latter, in those areas that may result in an antigenic site for cells T. The Fv fragment contains the variable domains of murine immunoglobuline. The invention also relates to the utilization of recombinant antibodies derived from murine antibody ior C5 in the diagnosis and therapy of colorectal tumors, the metastasis thereof and recurrences.
    Type: Grant
    Filed: November 16, 2000
    Date of Patent: May 10, 2005
    Assignee: Centro Inmunologia Molecular
    Inventors: Cristina Maria Mateo de Acosta Del Rio, Lourdes Tatiana Roque Navarro, Alejo Morales Morales, Rolando Pérez Rodríguez, Marta Ayala Ávila, Jorge Victor Gavilondo Cowley, Marta Dueñas Porto, Hanssel Bell García, Enrique Rengifo Calzado, Normando Iznaga Escobar, Mayra Ramos Zuzarte