Patents by Inventor Marta GIULIANI

Marta GIULIANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinazoline derivatives as LPA receptor 2 inhibitors
    Patent number: 12404270
    Abstract: The present invention relates to a compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are quinazoline derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: September 2, 2025
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Gabriele Amari, Elisabetta Armani, Mafalda Pagano, Luca Raveglia, Marta Giuliani, Claudia Beato
  • AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS
    Publication number: 20250188068
    Abstract: The present invention relates to compounds of general formula (I) inhibiting lysophosphatidic acid receptor 1 (LPA1), particularly the invention relates to compounds that are amido cyclopropyl derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Application
    Filed: March 7, 2023
    Publication date: June 12, 2025
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Elisabetta ARMANI, Gabriele AMARI, Mafalda PAGANO, Marta GIULIANI
  • CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS
    Publication number: 20250066341
    Abstract: The present invention relates to a compounds of general formula (I) inhibiting lysophosphatidic acid receptor 1 (LPA1), particularly the invention relates to compounds that are cyclohexane acid derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Application
    Filed: December 21, 2022
    Publication date: February 27, 2025
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Elisabetta ARMANI, Gabriele AMARI, Mafalda PAGANO, Marta GIULIANI
  • 8-CYCLO-SUBSTITUTED QUINAZOLINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS
    Publication number: 20240190860
    Abstract: The present invention relates to compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are 8-cyclo-substituted quinazoline derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Application
    Filed: March 24, 2021
    Publication date: June 13, 2024
    Inventors: Gabriele AMARI, Elisabetta ARMANI, Mafalda PAGANO, Marta GIULIANI, Luca RAVEGLIA, Claudia BEATO
  • QUINAZOLINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS
    Publication number: 20230063121
    Abstract: The present invention relates to a compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are quinazoline derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Application
    Filed: December 10, 2020
    Publication date: March 2, 2023
    Inventors: Gabriele AMARI, Elisabetta ARMANI, Mafalda PAGANO, Luca RAVEGLIA, Marta GIULIANI, Claudia BEATO