Patents by Inventor Marta Monjo
Marta Monjo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9849212Abstract: The present invention provides a biocompatible implant comprising one or more metal(s), metal alloy(s), metal oxide(s) or a combination thereof, wherein an antioxidant compound selected from the group of flavonoids or methoxytryptophols, an ester thereof, a pharmaceutically acceptable salt thereof or a combination thereof, is/are coated to at least a part of a metal, metal alloy or metal oxide surface of said biocompatible implant. This implant is useful for replace bone tissue in vertebrate animals, and furthermore restore the normal function of said tissue, mainly due to its ability of induce osseointegration and soft tissue attachment.Type: GrantFiled: April 18, 2013Date of Patent: December 26, 2017Assignee: NUMAT BIOMEDICAL S.L.Inventors: Marta Monjo Cabrer, Joana María Ramis Morey, Alba Córdoba Insensé, María Satué Sahún, Manuel Gómez Florit
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Patent number: 9433710Abstract: The present invention relates to a biocompatible implant comprising one or more metal(s), metal alloy(s), metal oxide(s) or a combination thereof, wherein a compound selected from the group consisting of an IP, an ester of an IP, and/or a pharmaceutically acceptable salt thereof, or a combination thereof, is/are covalently bound to at least a part of a metal, metal alloy or metal oxide surface of said biocompatible implant. The covalent bond between the IP and the metal, metal alloy or metal oxide surface can be further assisted by the use of a linker. An implant according to the invention provides for a modulated and/or improved osseointegrative effect when implanted into a body, such as a mammalian body, by virtue of the coating comprising covalently bound phytate.Type: GrantFiled: December 26, 2012Date of Patent: September 6, 2016Assignees: LABORATORIES SANIFIT, S. L., NUMAT BIOMEDICAL, S. L.Inventors: Marta Monjo Cabrer, Joan Perelló Bestard, Joana María Ramis Morey, Fernando Tur Espinosa, María del Mar Arriero Sánchez, Eva Martín Becerra, Bernat Isern Amengual, Rubén Henríquez Paláez
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Publication number: 20160082147Abstract: The present invention provides a biocompatible implant comprising one or more metal(s), metal alloy(s), metal oxide(s) or a combination thereof, wherein an antioxidant compound selected from the group of flavonoids or methoxytryptophols, an ester thereof, a pharmaceutically acceptable salt thereof or a combination thereof, is/are coated to at least a part of a metal, metal alloy or metal oxide surface of said biocompatible implant. This implant is useful for replace bone tissue in vertebrate animals, and furthermore restore the normal function of said tissue, mainly due to its ability of induce osseointegration and soft tissue attachment.Type: ApplicationFiled: April 18, 2013Publication date: March 24, 2016Applicant: NUMAT BIOMEDICAL S.L.Inventors: Marta MONJO CABRER, Joana María RAMIS MOREY, Alba CÓRDOBA INSENSÉ, María SATUÉ SAHÚN, Manuel GÓMEZ FLORIT
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Publication number: 20150004208Abstract: The present invention relates to a biocompatible implant comprising one or more metal(s), metal alloy(s), metal oxide(s) or a combination thereof, wherein a compound selected from the group consisting of an IP, an ester of an IP, and/or a pharmaceutically acceptable salt thereof, or a combination thereof, is/are covalently bound to at least a part of a metal, metal alloy or metal oxide surface of said biocompatible implant. The covalent bond between the IP and the metal, metal alloy or metal oxide surface can be further assisted by the use of a linker. An implant according to the invention provides for a modulated and/or improved osseointegrative effect when implanted into a body, such as a mammalian body, by virtue of the coating comprising covalently bound phytate.Type: ApplicationFiled: December 26, 2012Publication date: January 1, 2015Inventors: Marta Monjo Cabrer, Joan Perelló Bestard, Joana María Ramis Morey, Fernado Tur Espinosa, María del Mar Arriero Sánchez, Eva Martín Becerra, Bernat Isern Amengual, Rubén Henríquez Paláez
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Patent number: 8821568Abstract: An implant to be used as medical or dental implant, comprising a metallic or polymeric base which is covered by the vitamin D precursor cholecalciferol. The implant can be obtained by direct covering of the polymeric or metallic base with a solution comprising cholecalciferol or also covering the base with the 7-dehydrocholesterol (7-DHC), and subsequently irradiated with UV light to induce the formation of cholecalciferol. Optionally, the coating of the implant may include an antioxidant such as vitamin E. This implant enhances osseointegration in compromised patients by means of the endogenous synthesis and activity of vitamin D in hard and mineralized tissue regeneration. Furthermore, a method to obtain these implants which comprises coating the surface of the implant directly with cholecalciferol or with a specific concentration of 7-DHC and irradiated with UV light to induce the formation of cholecalciferol.Type: GrantFiled: July 26, 2012Date of Patent: September 2, 2014Assignee: Numat Biomedical S.L.Inventors: Ståle Petter Lyngstadaas, Marta Monjo, Christiane Petzold, Jan Erik Ellingsen
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Publication number: 20130017234Abstract: An implant to be used as medical or dental implant, comprising a metallic or polymeric base which is covered by the vitamin D precursor cholecalciferol. The implant can be obtained by direct covering of the polymeric or metallic base with a solution comprising cholecalciferol or also covering the base with the 7-dehydrocholesterol (7-DHC), and subsequently irradiated with UV light to induce the formation of cholecalciferol. Optionally, the coating of the implant may include an antioxidant such as vitamin E. This implant enhances osseointegration in compromised patients by means of the endogenous synthesis and activity of vitamin D in hard and mineralized tissue regeneration. Furthermore, a method to obtain these implants which comprises coating the surface of the implant directly with cholecalciferol or with a specific concentration of 7-DHC and irradiated with UV light to induce the formation of cholecalciferol.Type: ApplicationFiled: July 26, 2012Publication date: January 17, 2013Applicant: Numat Biomedical S.L.Inventors: Ståle Petter Lyngstadaas, Marta Monjo, Christlane Petzold, Jan Erik Ellingsen
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Publication number: 20110166670Abstract: A medical or dental implant which contains a metal material selected from the group consisting of titanium or an alloy thereof, wherein at least part of the surface of the metal material is coated with a layer of a polyunsaturated fatty acids (PUFA). In a preferred embodiment, the implant has been exposed to UV radiation for at least 30 seconds before, simultaneously with and/or after the coating with PUFA. Depending on the concentration of polyunsaturated fatty acids on the surface, at least parts of the implant exhibits improved effect on adhesion of mineralized and/or hard tissue, such as on bone remodeling and/or improved biocompatibility, or alternatively inhibits adhesion of mineralized and/or hard tissue to the implant. The metal material is preferably titanium, the polyunsaturated fatty acid is preferably EPA.Type: ApplicationFiled: May 29, 2009Publication date: July 7, 2011Inventors: Stale Petter Lyngstadaas, Marta Monjo, Christiane Petzold, Jan Erik Ellingsen