Abstract: The present disclosure relates to a new classes of water-soluble trypthantrin derivatives of Formula (I) and its salts or Formula (II) and its salts, and their use as soluble electrolytes (active materials) for aqueous organometallic and all-organic redox flow batteries (RFB) working at neutral pH with long-term stability. Electrochemical measurements show that water soluble trypthantrin derivatives display reversible peaks at several pH values, allowing its use as the anolyte together with organometallic and organic water-soluble catholytes in a neutral supporting electrolyte.