Abstract: The invention relates to an immunogenic or vaccine composition comprising an inactivated bacterium from the species Brachyspira hyodysenteriae, to a method for producing said composition and to the medical use of this composition for inducing an immune response against a bacterium from the species Brachyspira hyodysenteriae or for protecting against an infection caused by a bacterium from the species Brachyspira hyodysenteriae. Further, the invention relates to a method for selecting a bacterium from the species Brachyspira hyodysenteriae useful for manufacturing a vaccine against swine dysentery.

Abstract: The present invention provides a combination vaccine comprising one or more antigens of Mycoplasmahyopneumoniae, one or more antigens of Porcine circovirus, and pharmaceutically acceptable excipients and/or carriers, for use in the prevention and/or treatment of porcine enzootic pneumonia and/or Porcine Circovirus-Associated Diseases (PCVAD) by administration of the vaccine into the dermis of livestock, wherein the one or more antigens of porcine circovirus comprises the PCV2 ORF2 protein in an amount from 0.1 ?g/dose to 10 ?g/dose.

Abstract: The present invention relates to a method for preparing cDNA infectious clones based on the genome of an attenuated Porcine Reproductive and Respiratory Syndrome virus (PRRSV) and uses thereof for preparing efficacious and safety-enhanced vaccines against PRRSV. The invention further comprises an infectious cDNA clone obtainable by such method. The invention further provides an attenuated modified PRRSV, and immunogenic compositions and vaccines comprising that attenuated PRRSV. The present invention further provides the attenuated PRRSV for use in the prophylaxis and/or the treatment of PRRSV infections, and the attenuated PRRSV for use as vaccine or medicament in the prophylaxis and/or the treatment of PRRSV infections.

Abstract: The present invention relates to an immunogenic composition comprising one or more C. difficile toxoid for use in a medicament for animals. The invention also encompasses an immunogenic composition comprising one or more C. difficile A toxoid and one or more C. difficile B toxoid and one or more C. perfringens Type A toxoid. The invention also encompasses vaccines comprising said immunogenic compositions, vaccines for use in the treatment and/or prevention of disease caused by C. difficile and C. perfringens, and kits thereof.

Abstract: The present invention relates to an immunogenic composition comprising one or more C. difficile toxoid for use in a medicament for animals. The invention also encompasses an immunogenic composition comprising one or more C. difficile A toxoid and one or more C. difficile B toxoid and one or more C. perfringens Type A toxoid. The invention also encompasses vaccines comprising said immunogenic compositions, vaccines for use in the treatment and/or prevention of disease caused by C. difficile and C. perfringens, and kits thereof.

Abstract: The present invention relates to a method for preparing cDNA infectious clones based on the genome of an attenuated Porcine Reproductive and Respiratory Syndrome virus (PRRSV) and uses thereof for preparing efficacious and safety-enhanced vaccines against PRRSV. The invention further comprises an infectious cDNA clone obtainable by such method. The invention further provides an attenuated modified PRRSV, and immunogenic compositions and vaccines comprising that attenuated PRRSV. The present invention further provides the attenuated PRRSV for use in the prophylaxis and/or the treatment of PRRSV infections, and the attenuated PRRSV for use as vaccine or medicament in the prophylaxis and/or the treatment of PRRSV infections.

Abstract: The present invention relates to mutant strains of Mycoplasma hyopneumoniae and to a method for preparing them. It also relates to carrier vectors which are used in said method, to vaccine compositions and to vaccination kits comprising the compositions against porcine enzootic pneumonia and other swine diseases. It also relates to the use of M. hyopneumoniae as a host for expressing recombinant proteins and other DNA sequences of interest.

Abstract: The present invention relates to mutant strains of Mycoplasma hyopneumoniae and to a method for preparing them. It also relates to carrier vectors which are used in said method, to vaccine compositions and to vaccination kits comprising the compositions against porcine enzootic pneumonia and other swine diseases. It also relates to the use of M. hyopneumoniae as a host for expressing recombinant proteins and other DNA sequences of interest.