Patents by Inventor Martha Gray

Martha Gray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrodynamic capture and release mechanisms for particle manipulation
    Publication number: 20060128006
    Abstract: A cell analysis and sorting apparatus is capable of monitoring over time the behavior of each cell in a large population of cells. The cell analysis and sorting apparatus contains individually addressable cell locations. Each location is capable of capturing and holding a specified number of cells, and selectively releasing that specified number of cells from that particular location. In one aspect of the invention, the cells are captured and held in wells, and released using vapor bubbles as a means of cell actuation. Disclosed are: a cell manipulation apparatus design; various resistive heater configurations for nucleating microbubbles; various well designs, each in communication with a nucleation chamber or channel, for capturing a specified number of cells; and methods of fabrication and cell population manipulation.
    Type: Application
    Filed: June 7, 2005
    Publication date: June 15, 2006
    Inventors: Antimony Gerhardt, Gwendolyn Gerhardt, Rebecca Maxwell, Joel Voldman, Martha Gray, Martin Schmidt, Mehmet Toner
  • Cell sorting apparatus and methods for manipulating cells using the same
    Publication number: 20040166555
    Abstract: A cell analysis and sorting apparatus is capable of monitoring over time the behavior of each cell in a large population of cells. The cell analysis and sorting apparatus contains individually addressable cell locations. Each location is capable of capturing and holding a single cell, and selectively releasing that cell from that particular location. In one aspect of the invention, the cells are captured and held in wells, and released using vapor bubbles as a means of cell actuation. In another aspect of the invention, the cells are captured, held and released using electric field traps.
    Type: Application
    Filed: February 13, 2004
    Publication date: August 26, 2004
    Inventors: Rebecca Braff, Joel Voldman, Martha Gray, Martin Schmidt, Mehmet Toner
  • Cell analysis and sorting apparatus for manipulation of cells
    Patent number: 6692952
    Abstract: A cell analysis and sorting apparatus is capable of monitoring over time the behavior of each cell in a large population of cells. The cell analysis and sorting apparatus contains individually addressable cell locations. Each location is capable of capturing and holding a single cell, and selectively releasing that cell from that particular location. In one aspect of the invention, the cells are captured and held in wells, and released using vapor bubbles as a means of cell actuation. In another aspect of the invention, the cells are captured, held and released using electric field traps.
    Type: Grant
    Filed: November 10, 2000
    Date of Patent: February 17, 2004
    Assignee: Massachusetts Institute of Technology
    Inventors: Rebecca Braff, Joel Voldman, Martha Gray, Martin Schmidt, Mehmet Toner