Patents by Inventor Martha J. Smith

Martha J. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KRas G12D inhibitors
    Patent number: 11964989
    Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: April 23, 2024
    Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.
    Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
  • KRAS G12C INHIBITORS
    Publication number: 20240101553
    Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Application
    Filed: August 4, 2023
    Publication date: March 28, 2024
    Inventors: Matthew Arnold MARX, James Gail CHRISTENSEN, Christopher Ronald SMITH, James F. BLAKE, Laurence E. BURGESS, Mark Joseph CHICARELLI, Adam COOK, Jay Bradford FELL, John P. FISCHER, Macedonio J. MEJIA, Martha E. RODRIGUEZ, Pavel SAVECHENKOV, Tony P. TANG, Guy P.A. VIGERS
  • Undergarment
    Patent number: 4597110
    Abstract: A panty-type undergarment comprising a waistband connected to a body segment having front and back panels which terminate at leg openings, with a crotch segment located between the leg openings and a crotch opening situated between the leg openings and separating the crotch segment and the front panel along an edge of each extending generally parallel to the waistband, wherein the front panel adjacent to the crotch opening has first fastener means and the crotch segment adjacent to the crotch opening has second fastener means releasably engageable with the first fastener means so that the wearer can selectively open and close the crotch opening of the undergarment by selectively peeling apart and pressing together the first and second fastener means.
    Type: Grant
    Filed: November 19, 1984
    Date of Patent: July 1, 1986
    Assignee: Joe W. Johnson
    Inventors: James R. Smith, Sr., Martha J. Smith
  • Outergarment
    Patent number: 4578828
    Abstract: A novel and useful pants-type outergarment having a crotch opening and a padded fly attached to the interior of the outergarment on one side to the crotch opening seam line, beginning at a front placket of the outergarment and extending to the back waistband. First fastener means are provided on one side of the padded fly to cooperate with and releasably engage second fastener means provided on the inner thigh seam line adjacent to the crotch opening so that, when the two fastener means are engaged with each other, the padded fly cannot roll up while the garment is being worn, and third fastener means are provided to selectively close together and open apart the opposite sides of the crotch opening.
    Type: Grant
    Filed: November 19, 1984
    Date of Patent: April 1, 1986
    Assignee: Joe W. Johnson
    Inventors: James R. Smith, Sr., Martha J. Smith