Patents by Inventor Martha Knight

Martha Knight has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11365398
    Abstract: A spiral tube countercurrent chromatography rotor for separating virus in a two part aqueous solvent is described.
    Type: Grant
    Filed: November 29, 2020
    Date of Patent: June 21, 2022
    Assignee: CC Biotech LLC
    Inventor: Martha Knight
  • Publication number: 20220152523
    Abstract: A countercurrent chromatography method for separating cannabinoids using, for example, a solvent of hexane, methanol, ethyl acetate and water for separating THC and/or CBD, is provided.
    Type: Application
    Filed: March 2, 2020
    Publication date: May 19, 2022
    Inventor: Martha Knight
  • Publication number: 20210079361
    Abstract: A spiral tube countercurrent chromatography rotor for separating virus in a two part aqueous solvent is described.
    Type: Application
    Filed: November 29, 2020
    Publication date: March 18, 2021
    Inventor: Martha Knight
  • Patent number: 10851349
    Abstract: A spiral tube countercurrent chromatography rotor for separating virus in a two part aqueous solvent is described.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: December 1, 2020
    Inventor: Martha Knight
  • Publication number: 20190015761
    Abstract: A mixer-settler countercurrent chromatography centrifuge and rotor of increased capacity is described.
    Type: Application
    Filed: July 17, 2018
    Publication date: January 17, 2019
    Inventors: Martha Knight, Ben Feldman, Eric Cabahug
  • Patent number: 9713778
    Abstract: A method for constructing a spiral tube support apparatus used in countercurrent chromatography, improvements to countercurrent chromatography tube support design, and methods of using the improved countercurrent chromatography apparatus are described. The spiral tube support apparatus may be constructed by a shape forming process such as a three dimensional printing process that in turn uses a laser sintering technique, and can be made out of any easily formed material. Shape changes on both the tube support and the top improve the performance of the tube support and ease of manufacturing. The improved tube support and new method of creation permit use in both micro or macro scale preparations and use in small or large molecule preparations. In particular, specific solvent systems are described that permit purification of proteins.
    Type: Grant
    Filed: December 1, 2013
    Date of Patent: July 25, 2017
    Inventors: Martha Knight, Thomas Finn
  • Publication number: 20140091036
    Abstract: A method for constructing a spiral tube support apparatus used in countercurrent chromatography, improvements to countercurrent chromatography tube support design, and methods of using the improved countercurrent chromatography apparatus are described. The spiral tube support apparatus may be constructed by a shape forming process such as a three dimensional printing process that in turn uses a laser sintering technique, and can be made out of any easily formed material. Shape changes on both the tube support and the top improve the performance of the tube support and ease of manufacturing. The improved tube support and new method of creation permit use in both micro or macro scale preparations and use in small or large molecule preparations. In particular, specific solvent systems are described that permit purification of proteins.
    Type: Application
    Filed: December 1, 2013
    Publication date: April 3, 2014
    Applicant: CC Biotech LLC
    Inventors: Martha Knight, Thomas Finn
  • Patent number: 8597509
    Abstract: The present invention describes a method for constructing a spiral tube support apparatus used in countercurrent chromatography, improvements to countercurrent chromatography tube support design, and methods of using the improved countercurrent chromatography apparatus. The spiral tube support apparatus may be constructed by a shape forming process such as a three dimensional printing process that in turn uses a laser sintering technique, and can be made out of any easily formed material. Shape changes on both the tube support and the top improve the performance of the tube support and ease of manufacturing. The improved tube support and new method of creation permit use in both micro or macro scale preparations and use in small or large molecule preparations. In particular, specific solvent systems are described that permit purification of proteins.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: December 3, 2013
    Assignee: CC Biotech LLC
    Inventors: Martha Knight, Thomas M Finn
  • Publication number: 20120037567
    Abstract: The present invention describes a method for constructing a spiral tube support apparatus used in countercurrent chromatography, improvements to countercurrent chromatography tube support design, and methods of using the improved countercurrent chromatography apparatus. The spiral tube support apparatus may be constructed by a shape forming process such as a three dimensional printing process that in turn uses a laser sintering technique, and can be made out of any easily formed material. Shape changes on both the tube support and the top improve the performance of the tube support and ease of manufacturing. The improved tube support and new method of creation permit use in both micro or macro scale preparations and use in small or large molecule preparations. In particular, specific solvent systems are described that permit purification of proteins.
    Type: Application
    Filed: November 18, 2009
    Publication date: February 16, 2012
    Applicant: CC BIOTECH LLC
    Inventors: Martha Knight, Thomas Finn
  • Patent number: 5965524
    Abstract: This invention is directed to the analogs of viscosin, pharmaceutical compositions thereof and to methods of using viscosin and analogs thereof as biosurfactants and as antibacterial, antiviral and antitrypanosomal therapeutic compounds. In particular, compositions that inhibit the growth of the pathogens Mycobacterium tuberculosis, Herpes Simplex Virus 2 and/or Trypanosoma cruzi are disclosed.
    Type: Grant
    Filed: September 6, 1994
    Date of Patent: October 12, 1999
    Assignee: Peptide Technologies Corporation
    Inventors: Terrance Burke, Jr., Bhaskar Chandrasekhar, Martha Knight
  • Patent number: 5620955
    Abstract: Bombesin is an amphibian peptide that has a structure closely related to that of several mammalian peptides, including Gastrin Releasing Peptide (GRP) and Neuromedins B and C. Bombesin, GRP and related peptides exert their in vivo effects by binding to specific receptors present on cells of the gastrointestinal tract, the central nervous system, and tumors. The invention relates to novel bombesin derivatives which act as bombesin receptor antagonists by blocking the binding of bombesin, GRP or related peptides to cellular receptors. By blocking the binding of bombesin, GRP and related peptides to cellular receptors on cancer cells, these antagonists inhibit the growth of tumor cells that respond to the growth-promoting action of bombesin. These antagonists are expected to block the binding of bombesin, GRP or related peptides to similar receptors on cells in the gastrointestinal tract or the central nervous system.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: April 15, 1997
    Assignee: Peptide Technologies Corporation
    Inventors: Martha Knight, Kazuyuki Takahashi, Bhaskar Chandrasekhar
  • Patent number: 5169862
    Abstract: This invention is directed to the analogs of viscosin, pharmaceutical compositions thereof and to their use as antibacterial, antiviral and antitrypanosomal therapeutic compounds.
    Type: Grant
    Filed: November 18, 1991
    Date of Patent: December 8, 1992
    Assignee: Peptide Technologies Corporation
    Inventors: Terrence Burke, Jr., Bhaskar Chandrasekhar, Martha Knight