Patents by Inventor Martha KOUKIDOU

Martha KOUKIDOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene Expression System
    Publication number: 20240016132
    Abstract: Two or more conditional, dominant, lethal gene expression systems provide high levels of penetrance in insects. Lethality is induced at an earlier stage of development and the risk of biochemical resistance is reduced, as compared to a single insect conditional, dominant, lethal gene expression system. The invention is useful for the control of insect populations.
    Type: Application
    Filed: July 14, 2023
    Publication date: January 18, 2024
    Applicant: Oxitec Limited
    Inventors: Martha Koukidou, Luke Alphey, Simon Warner
  • Gene expression system
    Patent number: 11737436
    Abstract: Two or more conditional, dominant, lethal gene expression systems provide high levels of penetrance in insects. Lethality is induced at an earlier stage of development and the risk of biochemical resistance is reduced, as compared to a single insect conditional, dominant, lethal gene expression system. The invention is useful for the control of insect populations.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: August 29, 2023
    Assignee: Oxitec Limited
    Inventors: Martha Koukidou, Luke Alphey, Simon Warner
  • Self-Selecting Sterile Male Arthropods
    Publication number: 20210324409
    Abstract: The invention provides a gene expression system that imparts homozygous, sex-specific lethality in arthropods, particularly Tephritid insects, such as Ceratitis capitata. The arthropod strains produce males that are also engineered to be sterile. The sterile may be released to mate with wild female to suppress propagation of the arthropod population.
    Type: Application
    Filed: August 13, 2019
    Publication date: October 21, 2021
    Inventors: Ryan Turkel, Martha Koukidou, Tarig Dafa'alla, Nathan Rose, Romisa Asadi, Simon Warner
  • Gene Expression System
    Publication number: 20210137083
    Abstract: Two or more conditional, dominant, lethal gene expression systems provide high levels of penetrance in insects. Lethality is induced at an earlier stage of development and the risk of biochemical resistance is reduced, as compared to a single insect conditional, dominant, lethal gene expression system. The invention is useful for the control of insect populations.
    Type: Application
    Filed: August 19, 2020
    Publication date: May 13, 2021
    Inventors: Martha Koukidou, Luke Alphey, Simon Warner
  • Insect muscle actin promoter
    Patent number: 10426147
    Abstract: Provided is a gene expression system, suitable for expression in an insect, comprising an insect muscle actin promoter operably linked to a marker gene, which overcomes or ameliorates one or more of: cost of rearing; amount of handling; errors in identification due to human error or loss of marker by the insect; and health concerns related to the effects of marker powders on workers in mass rearing facilities.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: October 1, 2019
    Assignee: Oxitec Limited
    Inventors: Martha Koukidou, Sarah Scaife, Luke Alphey
  • INSECT MUSCLE ACTIN PROMOTER
    Publication number: 20170360015
    Abstract: Provided is a gene expression system, suitable for expression in an insect, comprising an insect muscle actin promoter operably linked to a marker gene, which overcomes or ameliorates one or more of: cost of rearing; amount of handling; errors in identification due to human error or loss of marker by the insect; and health concerns related to the effects of marker powders on workers in mass rearing facilities.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 21, 2017
    Applicant: Oxitec Limited
    Inventors: Martha KOUKIDOU, Sarah SCAIFE, Luke ALPHEY
  • GENE EXPRESSION SYSTEM
    Publication number: 20170188559
    Abstract: Two or more conditional, dominant, lethal gene expression systems provide high levels of penetrance in insects. Lethality is induced at an earlier stage of development and the risk of biochemical resistance is reduced, as compared to a single insect conditional, dominant, lethal gene expression system. The invention is useful for the control of insect populations.
    Type: Application
    Filed: June 4, 2015
    Publication date: July 6, 2017
    Applicant: Oxitec Limited
    Inventors: Martha KOUKIDOU, Luke ALPHEY, Simon WARNER
  • INSECT MUSCLE ACTIN PROMOTER
    Publication number: 20160106078
    Abstract: Provided is a gene expression system, suitable for expression in an insect, comprising an insect muscle actin pro-moter operably linked to a marker gene, which overcomes or ameliorates one or more of: cost of rearing; amount of handling; errors in identification due to human error or loss of marker by the insect; and health concerns related to the effects of marker powders on workers in mass rearing facilities.
    Type: Application
    Filed: March 5, 2014
    Publication date: April 21, 2016
    Applicant: Oxitec Limited
    Inventors: Martha KOUKIDOU, Sarah SCAIFE, Luke ALPHEY