Patents by Inventor Martha L. Bulyk

Martha L. Bulyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Space efficient polymer sets
    Patent number: 8530638
    Abstract: The disclosure features a collection that comprises a plurality of polymers, typically nucleic acid molecules in a compact form. The molecules include all possible sequences or at least a certain percentage of all possible sequences, of a particular length.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: September 10, 2013
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Martha L. Bulyk, Anthony A. Philippakis, Preston Wayne Estep
  • SPACE EFFICIENT POLYMER SETS
    Publication number: 20100267572
    Abstract: The disclosure features a collection that comprises a plurality of polymers, typically nucleic acid molecules in a compact form. The molecules include all possible sequences or at least a certain percentage of all possible sequences, of a particular length.
    Type: Application
    Filed: June 28, 2010
    Publication date: October 21, 2010
    Applicant: THE BRIGHAM AND WOMENS HOSPITAL, INC.
    Inventors: Martha L. Bulyk, Anthony A. Philippakis, Preston Wayne Estep
  • Surface-bound, double-stranded DNA protein arrays
    Publication number: 20030215856
    Abstract: The invention provides a synthetic array of surface-bound, bimolecular, double-stranded nucleic acid molecules, the array comprising a solid support and a plurality of bimolecular double-stranded nucleic acid molecule members, a member comprising a first nucleic acid strand linked to the solid support and a second nucleic acid strand which is substantially complementary to the first strand and complexed to the first strand by Watson-Crick base pairing, wherein for at least a portion of the members, each member comprises a recognition site within a nucleic acid sequence for a protein, wherein a recognition site within a nucleic acid sequence for a protein of a first member is different from a recognition site within a nucleic acid sequence for a protein of a second member and wherein a protein is bound to a member thereof.
    Type: Application
    Filed: April 1, 2003
    Publication date: November 20, 2003
    Applicant: President and Fellows of Harvard College
    Inventors: George M. Church, Martha L. Bulyk
  • Surface-bound, double-stranded DNA protein arrays
    Patent number: 6548021
    Abstract: The invention provides a synthetic array of surface-bound, bimolecular, double-stranded nucleic acid molecules, the array comprising a solid support and a plurality of bimolecular double-stranded nucleic acid molecule members, a member comprising a first nucleic acid strand linked to the solid support and a second nucleic acid strand which is substantially complementary to the first strand and complexed to the first strand by Watson-Crick base pairing, wherein for at least a portion of the members, each member comprises a recognition site within a nucleic acid sequence for a protein, wherein a recognition site within a nucleic acid sequence for a protein of a first member is different from a recognition site within a nucleic acid sequence for a protein of a second member and wherein a protein is bound to a member thereof.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: April 15, 2003
    Assignee: President and Fellows of Harvard College
    Inventors: George M. Church, Martha L. Bulyk
  • Surface-bound, bimolecular, double-stranded DNA arrays
    Patent number: 6326489
    Abstract: The invention provides an array of surface-bound, bimolecular, double-stranded, nucleic acid molecules, the array comprising a solid support, and a plurality of different double-stranded nucleic acid molecule members, a member comprising a first nucleic acid strand linked to the solid support and a second nucleic acid strand which is substantially complementary to the first strand and complexed to the first strand by Watson-Crick base pairing, wherein at least a portion of the members have a second nucleic acid strand is substantially complementary to and base paired with the first strand along the entire length of the first strand.
    Type: Grant
    Filed: August 5, 1997
    Date of Patent: December 4, 2001
    Assignees: Howard Hughes Medical Institute, President & Fellows of Harvard College
    Inventors: George M. Church, Martha L. Bulyk