Patents by Inventor Martin A. Clements
Martin A. Clements has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090148309Abstract: Vane pump (10) mechanical losses are reduced by removing vane friction losses and replacing them with lower magnitude journal bearing fluid film viscous drag losses. A freely rotating cam ring (70) is supported by a journal bearing (80). A relatively low sliding velocity is imposed between the cam ring and the vanes (26). This permits the use of less expensive and less brittle materials in the pump by allowing the pump to operate at much higher speeds without concern for exceeding vane tip velocity limits.Type: ApplicationFiled: February 16, 2009Publication date: June 11, 2009Inventors: MARTIN A. CLEMENTS, Lowell D. Hansen
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Publication number: 20090068125Abstract: This invention relates to a medicament for protecting human mucosal cells from chemotherapy or radiotherapy induced cell death using formulations comprising adenosine or adenosine analogues as a reversible inhibitor of epithelial cell proliferation. The invention also relates to formulations containing adenosine for the prevention of or reduction in mucositis symptoms.Type: ApplicationFiled: January 25, 2006Publication date: March 12, 2009Applicant: HEPTAGEN LTDInventors: Richard Mark Edwards, John Martin Clements
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Patent number: 7491043Abstract: Vane pump (10) mechanical losses are reduced by removing vane friction losses and replacing them with lower magnitude journal bearing fluid film viscous drag losses. A freely rotating cam ring (70) is supported by a journal bearing (80). A relatively low sliding velocity is imposed between the cam ring and the vanes (26). This permits the use of less expensive and less brittle materials in the pump by allowing the pump to operate at much higher speeds without concern for exceeding vane tip velocity limits.Type: GrantFiled: August 4, 2006Date of Patent: February 17, 2009Assignee: Argo-Tech CorporationInventors: Martin A. Clements, Lowell D. Hansen
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Publication number: 20080229726Abstract: A fuel delivery system (10) comprises a variable displacement pump (20) for pressurizing fuel. The variable displacement pump has a distinct first pump displacement setting for a first desired mass flow of fuel and a distinct second pump displacement setting for a second desired mass flow of fuel. The variable displacement pump operates in only one of the first and second pump displacement settings. A fuel control (22) with a metering valve downstream of the variable displacement pump selectively regulates fuel delivery.Type: ApplicationFiled: March 29, 2005Publication date: September 25, 2008Inventor: Martin A. Clements
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Publication number: 20080075786Abstract: Methods for interfering with the growth of fungi by exposing the fungi to an antimicrobial agent derived from cream, and more particularly, to methods for treating human fungal pathogens such as Candida albicans and Aspergillus fumigatus, through exposing the fungi to free fatty acids with antimicrobial activity derived from cream.Type: ApplicationFiled: October 13, 2006Publication date: March 27, 2008Applicant: Universite de MontrealInventors: Michel Lange, Martin Clement, Jessy Tremblay, Jacques Thibodeau, Pierre Belhumeur, Julie Shareck
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Patent number: 7323448Abstract: Compounds of formula (I) or a pharmaceutically or veterinarily acceptable salts thereof wherein R1 represents hydrogen, C1-C6 alkyl or C1-C6 alkyl substituted by one or more halogen atoms; R2 represents a group R10-(ALK)m-, and A represents (i) a group of formula (IA): wherein the compounds inhibit the activity of bacterial PDF enzyme.Type: GrantFiled: August 2, 2006Date of Patent: January 29, 2008Assignee: British Biotech Pharmaceuticals Ltd.Inventors: Michael George Hunter, Raymond Paul Beckett, John Martin Clements, Mark Whittaker, Stephen John Davies, Lisa Marie Pratt, Zoe Marie Spavold, Steven Launchbury
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Patent number: 7323563Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:Type: GrantFiled: August 22, 2005Date of Patent: January 29, 2008Assignee: British Biotech Pharmaceuticals Ltd.Inventors: Michael George Hunter, Paul Raymond Beckett, John Martin Clements, Mark Whittaker, Zoe Marie Spavold
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Publication number: 20070189740Abstract: The present invention provides a heat exchange system for a closed loop fuel delivery system. The heat exchange system generally includes a first pump, a heat exchanger, a high pressure pump pressurizes fuel. The heat exchanger, which is located downstream of the first pump, receives the pressurized fuel flow. The high pressure pump, which is located downstream of the heat exchanger, delivers a predetermined amount of fuel flow to a jet engine. The circulating pump receives fuel flow downstream of the heat exchanger and recirculates the fuel flow upstream of the heat exchanger.Type: ApplicationFiled: June 21, 2005Publication date: August 16, 2007Inventor: Martin Clements
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Patent number: 7247008Abstract: A bearing assembly is provided for a fuel delivery system that includes a pump (10) having a housing that rotatably receives a rotor (20) carrying vanes (26) thereon, a cam ring (70) received between the housing and rotor (20), and a support member of yoke (50) encompassing the cam ring (70) to selectively vary fuel flow. The bearing assembly (80) is a journal bearing between the yoke (50) and the cam ring (70) and includes an annular surface having a central opening therethrough. The annular surface includes a first, high pressure pad (102) and a second, low pressure pad (104) substantially diametrically opposite the first pad and separated by first and second lands (106, 108). The circumferential extent of the first pad (102) is at least as great as an inner diameter of the cam ring (70). Circumferential ends of the second pad (104) are wider than circumferential ends of the first pad.Type: GrantFiled: July 21, 2003Date of Patent: July 24, 2007Assignee: Argo-Tech CorporationInventors: Martin A. Clements, Robert Nyzen
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Patent number: 7148198Abstract: A compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof for the inhibition of activity of bacterial PDF enzyme: wherein A represents a group of formula (IA) or (IB) and wherein R1 is hydrogen, R2 is n-butyl, benzyl or cyclopentylmethyl, R3 is hydrogen, R4 is tert-butyl, iso-butyl, benzyl or methyl, R5 is hydrogen or methyl and R6 is methyl.Type: GrantFiled: July 29, 2004Date of Patent: December 12, 2006Assignee: British Biotech Pharmaceuticals, Ltd.Inventors: Michael George Hunter, Raymond Paul Beckett, John Martin Clements, Mark Whittaker, Stephen John Davies, Lisa Marie Pratt, Zoe Marie Spavold, Steven Launchbury
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Publication number: 20060269423Abstract: Vane pump (10) mechanical losses are reduced by removing vane friction losses and replacing them with lower magnitude journal bearing fluid film viscous drag losses. A freely rotating cam ring (70) is supported by a journal bearing (80). A relatively low sliding velocity is imposed between the cam ring and the vanes (26). This permits the use of less expensive and less brittle materials in the pump by allowing the pump to operate at much higher speeds without concern for exceeding vane tip velocity limits.Type: ApplicationFiled: August 4, 2006Publication date: November 30, 2006Inventors: Martin Clements, Lowell Hansen
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Publication number: 20060211732Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:Type: ApplicationFiled: August 22, 2005Publication date: September 21, 2006Applicant: British Biotech Pharmaceuticals Ltd.Inventors: Michael George Hunter, Raymond Beckett, John Martin Clements, Mark Whittaker, Zoe Spavold
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Patent number: 7108493Abstract: Vane pump (10) mechanical losses are reduced by removing vane friction losses and replacing them with lower magnitude journal bearing fluid film viscous drag losses. A freely rotating cam ring (70) is supported by a journal bearing (80). A relatively low sliding velocity is imposed between the cam ring and the vanes (26). This permits the use of less expensive and less brittle materials in the pump by allowing the pump to operate at much higher speeds without concern for exceeding vane tip velocity limits.Type: GrantFiled: March 27, 2002Date of Patent: September 19, 2006Assignee: Argo-Tech CorporationInventors: Martin A. Clements, Lowell D. Hansen
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Publication number: 20060099100Abstract: A bearing assembly is provided for a fuel delivery system that includes a pump (10) having a housing that rotatably receives a rotor (20) carrying vanes (26) thereon, a cam ring (70) received between the housing and rotor (20), and a support member of yoke (50) encompassing the cam ring (70) to selectively vary fuel flow. The bearing assembly (80) is a journal bearing between the yoke (50) and the cam ring (70) and includes an annular surface having a central opening therethrough. The annular surface includes a first, high pressure pad (102) and a second, low pressure pad (104) substantially diametrically opposite the first pad and separated by first and second lands (106, 108). The circumferential extent of the first pad (102) is at least as great as an inner diameter of the cam ring (70). Circumferential ends of the second pad (104) are wider than circumferential ends of the first pad.Type: ApplicationFiled: July 21, 2003Publication date: May 11, 2006Inventors: Martin Clements, Robert Nyzen
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Patent number: 6992190Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:Type: GrantFiled: June 26, 2002Date of Patent: January 31, 2006Assignee: British Biotech Pharmaceuticals Ltd.Inventors: Michael George Hunter, Paul Raymond Beckett, John Martin Clements, Mark Whittaker, Zoe Marie Spavold
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Patent number: 6908911Abstract: Selected compounds of formula (I) are antibacterial agents: formula (I) wherein R2 represents a substituted or unsubstituted C1-C6 alkyl, cycloalkyl (C1-C6 alkyl)- or aryl (C1-C6 alkyl)-group, and A represents a group of formula (IA), or (IB) wherein R4 represents the side chain of a natural or non-natural alpha amino acid, and R5 and R6 are each independently hydrogen or C1-C6 alkyl, heterocyclic or aryl (C1-C6 alkyl)-, R5 and R6 when taken together with the nitrogen atom to which they are attached from an optionally substituted saturated heterocyclic ring of 3 to 8 atoms which ring is optionally fused to a carbocyclic or second heterocyclic ringType: GrantFiled: August 10, 1999Date of Patent: June 21, 2005Assignee: British Biotech Pharmaceuticals LimitedInventors: Michael George Hunter, Raymond Paul Beckett, John Martin Clements, Mark Whittaker, Stephen John Davies, Lisa Marie Pratt, Zoe Marie Spavold, Steven Launchbury
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Patent number: 6810674Abstract: A fuel delivery system provides for closed loop mass flow control of fuel between a metering valve and a pump, such as a variable delivery pump. Changes in pressure across the metering valve are monitored and pump operation is altered in response thereto. A thermal controller monitors fuel temperature and recirculates a portion of the fuel flow through a heat exchanger. The fuel delivery system can be provided as original equipment or as a retrofit.Type: GrantFiled: July 18, 2002Date of Patent: November 2, 2004Assignee: Argo-Tech CorporationInventor: Martin A. Clements
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Patent number: 6787522Abstract: Compounds of formula (I) are antibacterials: wherein: R1 represents hydrogen, or C1-C6 alkyl or C1-C6 alkyl substituted by one or more halogen atoms; R2 represents a group R10—(X)n—(ALK)m— wherein R10 represents hydrogen, or a C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, cycloalkyl, aryl, or heterocyclyl group, any of which may be unsubstituted or substituted by (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy, mercapto, (C1-C6)alkylthio, amino, halo (including fluoro, chloro, bromo and iodo), trifluoromethyl, cyano, nitro, —COOH, —CONH2, —COORA, —NHCORA, —CONHRA, —NHRA, —NRARB, or —CONRARB wherein RA and RB are independently a (C1-C6)alkyl group, and ALK represents a straight or branched divalent C1-C6 alkylene, C2-C6 alkenylene, or C2-C6 alkynylene radical, and may be interrupted by one or more non-adjacent —NH—, —O— or —S— linkages, X represents —NH—, —O— or —S—, anType: GrantFiled: April 30, 2002Date of Patent: September 7, 2004Assignee: British Biotech PharmaceuticalsInventors: Michael George Hunter, Raymond Paul Beckett, John Martin Clements, Mark Whittaker, Stephen John Davies, Lisa Marie Pratt, Zoe Marie Spavold, Steven Launchbury
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Publication number: 20040136853Abstract: Vane pump (10) mechanical losses are reduced by removing vane friction losses and replacing them with lower magnitude journal bearing fluid film viscous drag losses. A freely rotating cam ring (70) is supported by a journal bearing (80). A relatively low sliding velocity is imposed between the cam ring and the vanes (26). This permits the use of less expensive and less brittle materials in the pump by allowing the pump to operate at much higher speeds without concern for exceeding vane tip velocity limits.Type: ApplicationFiled: October 3, 2003Publication date: July 15, 2004Inventors: Martin A. Clements, Lowell D. Hansen
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Patent number: 6723569Abstract: A dropping tool for transferring drops of a liquid onto a substrate wherein a surface of the dropping tool for contact with the liquid has a first region which exhibits an affinity to the liquid to be transferred directly surrounded by a second region which exhibits a lower affinity to the liquid to be transferred than the first region; the topography of the first and second regions and the relative affinities of the first and second regions for the liquid to be transferred being selected such that when the dropping tool is dipped into and then removed from a source of the liquid to be transferred, the liquid adheres to the first region without substantially any adherence of the liquid to the second region. A dropping tool for transferring drops of liquid onto a substrate, the dropping tool comprising a tip, at least one surface tapered towards the tip, and a capillary channel which leads from a position of the tapered surface remote from the tip to a reservoir located within the dropping tool.Type: GrantFiled: August 13, 2001Date of Patent: April 20, 2004Assignee: Genomic Solutions Acquisitions LimitedInventors: David Frank Moore, William Ireland Milne, Martin Clement Davies, Stuart Antony Elmes