Abstract: A retrofittable remote control system is provided for enabling remote controlling of an on-board component of machine that is inherently incapable of being remote controlled. An interface control module is retrofitted on machine and is configured to communicate with off-board remote control over wireless communication channel. The interface control module detects presence of an on-board control module that communicates with the on-board component over a digital communication channel. The interface control module is configured to then establish either a digital communication link with the on-board control module or a direct Input/Output (I/O) communication link with the on-board component of the machine based on the detection. The interface control module is configured to send a control signal over either the direct I/O communication link or the digital communication channel via the detected on-board control module, for controlling the on-board component.

Abstract: The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods useful for detecting and treating esophageal cancer. In a specific embodiment, a method for identifying a subject having esophageal adenocarcinoma (EAC) comprises (a) extracting genomic DNA from a sample obtained from the subject; (b) performing a conversion reaction on the genomic DNA in vitro to convert unmethylated cytosine to uracil by deamination; and (c) detecting nucleic acid methylation of one or more genes in the converted genomic DNA, wherein detecting nucleic acid methylation identifies the subject as having EAC. The one or more genes can comprise ABCB1, BMP3, COL23A1, FBN1, FADS1 and PRDM2. In a more specific embodiment, the one or more genes comprise at least three of ABCB1, BMP3, COL23A1, FBN1, FADS1 and PRDM2.

Abstract: This application presents to an endoscope having a compact distal tip, and to a method for constructing same. In some embodiments one or more optical and sensing elements are mounted directly on an internal surface of a lumen within an external housing, which housing comprises an outer wall of the endoscope tip. Space saved by eliminating intervening containing elements can be used to enhance endoscope performance and/or reduce endoscope size.

Abstract: The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods useful for detecting and treating esophageal cancer. In a specific embodiment, a method for identifying a subject having esophageal squamous cell carcinoma (ESCC) comprises (a) extracting genomic DNA from a sample obtained from the subject; (b) performing a conversion reaction on the genomic DNA in vitro to convert unmethylated cytosine to uracil by deamination; and (c) detecting nucleic acid methylation of one or more genes in the converted genomic DNA, wherein detecting nucleic acid methylation e identifies the subject as having ESCC. The one or more genes can comprise ZNF542, ZNF132, cg20655070, TAC1 and SLC35F1. In a more specific embodiment, the one or more genes comprise ZNF542 and ZNF132 and can further comprise detecting the nucleic acid N methylation of one or more of cg20655070, TAC1 and SLC35F1.

Abstract: This application presents to an endoscope having a compact distal tip, and to a method for constructing same. In some embodiments one or more optical and sensing elements are mounted directly on an internal surface of a lumen within an external housing, which housing comprises an outer wall of the endoscope tip. Space saved by eliminating intervening containing elements can be used to enhance endoscope performance and/or reduce endoscope size.

Abstract: This application presents to an endoscope having a compact distal tip, and to a method for constructing same. In some embodiments one or more optical and sensing elements are mounted directly on an internal surface of a lumen within an external housing, which housing comprises an outer wall of the endoscope tip. Space saved by eliminating intervening containing elements can be used to enhance endoscope performance and/or reduce endoscope size.

Abstract: An optical system, including: (a) an emitter array including a plurality of individual emitters, wherein each emitter in the emitter array is operable to emit a light beam which is characterized by a native beam width; (b) an optical subunit, operable to transform a plurality of light beams emitted by the emitter array, wherein each of the transformed light beams is characterized by an expanded beam width that is wider than the native beam width of the corresponding light beam and is wider than a facilitating beam width; and (c) a diffractive optical element that is capable of diffracting the transformed light beams to provide light patterns whose angular resolution meets a light pattern target angular resolution criteria.

Abstract: An optical system, including: (a) an emitter array including a plurality of individual emitters, wherein each emitter in the emitter array is operable to emit a light beam which is characterized by a native beam width; (b) an optical subunit, operable to transform a plurality of light beams emitted by the emitter array, wherein each of the transformed light beams is characterized by an expanded beam width that is wider than the native beam width of the corresponding light beam and is wider than a facilitating beam width; and (c) a diffractive optical element that is capable of diffracting the transformed light beams to provide light patterns whose angular resolution meets a light pattern target angular resolution criteria.

Abstract: This application presents to an endoscope having a compact distal tip, and to a method for constructing same. In some embodiments one or more optical and sensing elements are mounted directly on an internal surface of a lumen within an external housing, which housing comprises an outer wall of the endoscope tip. Space saved by eliminating intervening containing elements can be used to enhance endoscope performance and/or reduce endoscope size.

Abstract: This application presents to an endoscope having a compact distal tip, and to a method for constructing same. In some embodiments one or more optical and sensing elements are mounted directly on an internal surface of a lumen within an external housing, which housing comprises an outer wall of the endoscope tip. Space saved by eliminating intervening containing elements can be used to enhance endoscope performance and/or reduce endoscope size.

Abstract: Fluorescence imaging illumination fiber including a first fiber, a second fiber, and a diffuser, the second fiber concentrically enfolding the first fiber, the diffuser is coupled at the end of the first fiber and the second fiber, the first fiber having a first angular output, the second fiber having a second angular output, the diffuser increasing the first angular output by a first value and increasing the second angular output by a second value, the first value exceeding the second value.

Abstract: The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods for treating cancer using aqueous 32P. In certain embodiments, the present invention provides a method for treating cancer in a patient comprising the step of intravenously administering a low dose of aqueous 32P monophosphate or 32P pyrophosphate to the patient.

Abstract: An optical system, including: (a) an emitter array including a plurality of individual emitters, wherein each emitter in the emitter array is operable to emit a light beam which is characterized by a native beam width; (b) an optical subunit, operable to transform a plurality of light beams emitted by the emitter array, wherein each of the transformed light beams is characterized by an expanded beam width that is wider than the native beam width of the corresponding light beam and is wider than a facilitating beam width; and (c) a diffractive optical element that is capable of diffracting the transformed light beams to provide light patterns whose angular resolution meets a light pattern target angular resolution criteria.

Abstract: There is provided according to aspects of the present disclosure a structured light projector, a method of projecting a structured light pattern, and a depth sensing device. The projector includes an emitters array and a mask. The emitters array includes a plurality of individual light emitters. The light from each of the individual emitters diverges. The emitters array has a spatial intensity profile that is associated with the light divergence output of the array's individual emitters. The mask is designed to provide a structured light pattern when illuminated, and is positioned at a distance relative to the emitters array where rays from adjacent emitters overlap, and where such overlaps provide uniform light intensity distribution across the mask plane.

Abstract: Fluorescence imaging illumination fiber including a first fiber, a second fiber, and a diffuser, the second fiber concentrically enfolding the first fiber, the diffuser is coupled at the end of the first fiber and the second fiber, the first fiber having a first angular output, the second fiber having a second angular output, the diffuser increasing the first angular output by a first value and increasing the second angular output by a second value, the first value exceeding the second value.

Abstract: A 3D imaging apparatus comprising a projector, comprising a laser array comprising a plurality of individual emitters, a mask for providing a structured light pattern, wherein a distance between the laser array and the mask is substantially minimized according to a non-uniformity profile of the plurality of individual emitters and according to a uniformity criterion related to the light intensity distribution across the mask plane, projection optics to image the structured light pattern onto an object, an imaging sensor adapted to capture an image of the object with the structured light pattern projected thereon and a processing unit adapted to process the image to determine range parameters.

Abstract: Cancers are extremely heterogeneous in terms of the frequency and types of mutations present in different malignant tumors. Thus, it is likely that uniform clinical treatment is not optimal for all patients, and that the development of individualized therapeutic regimens may be beneficial. Multiple, unique small peptides bind to cell lines derived from different colon adenocarcinomas. Within two hours of contact, the colorectal cancer cells are able to transfer a 32P radioisotope from the small peptides to cellular proteins; the transfer occurs at a substantially higher rate than in the colorectal cancer cells than in cell lines derived from other cancers or from normal tissues.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.