Patents by Inventor Martin Acquadro

Martin Acquadro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12329513
    Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: June 17, 2025
    Inventors: Michael Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen
  • Patent number: 12207936
    Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: January 28, 2025
    Assignee: BRAINSTEM BIOMETRICS, INC.
    Inventors: Michael Baltay, Bruce Rasmussen, Yahya Shehabi, Ciaran Bolger, Martin Acquadro, Clark B. Foster
  • Publication number: 20210236051
    Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.
    Type: Application
    Filed: January 11, 2021
    Publication date: August 5, 2021
    Inventors: Michael Baltay, Bruce Rasmussen, Yahya Shehabi, Ciaran Bolger, Martin Acquadro, Clark B. Foster
  • Publication number: 20210113115
    Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.
    Type: Application
    Filed: December 7, 2020
    Publication date: April 22, 2021
    Inventors: Michael Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen
  • Patent number: 10888268
    Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brainstem activity is provided. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient is also provided.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: January 12, 2021
    Inventors: Michael Baltay, Bruce Rasmussen, Yahya Shehabi, Ciaran Bolger, Martin Acquadro, Clark B. Foster
  • Patent number: 10856774
    Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: December 8, 2020
    Inventors: Michael M Baltay, Clark B Foster, Ciaran Bolger, Martin Acquadro, Bruce A Rasmussen
  • Publication number: 20180160968
    Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brainstem activity is provided. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient is also provided.
    Type: Application
    Filed: December 8, 2016
    Publication date: June 14, 2018
    Inventors: Michael Baltay, Bruce Rasmussen, Yahya Shehabi, Ciaran Bolger, Martin Acquadro, Clark B. Foster
  • Publication number: 20180116558
    Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.
    Type: Application
    Filed: October 16, 2017
    Publication date: May 3, 2018
    Inventors: Michael M. Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen
  • Patent number: 9788760
    Abstract: An ocular micro tremor (OMT) sensor, system and method for measuring micromovements of an individual's eyeball having an amplitude of 40 micrometers or less to provide a variable voltage biosignal for measuring the individual's brain stem activity. The OMT sensor includes a flexible piezo-active sensing element mounted at the individual's closed or opened eyelid so as to be deflected by the micromovements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the piezo-active sensing element to an OMT amplifier located on the individual's skin where the biosignal is amplified. The OMT amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: October 17, 2017
    Inventors: Michael M Baltay, Clark B Foster, Ciaran Bolger, Martin Acquadro, Bruce A Rasmussen
  • Publication number: 20170156637
    Abstract: An ocular micro tremor (OMT) sensor, system and method for measuring micromovements of an individual's eyeball having an amplitude of 40 micrometers or less to provide a variable voltage biosignal for measuring the individual's brain stem activity. The OMT sensor includes a flexible piezo-active sensing element mounted at the individual's closed or opened eyelid so as to be deflected by the micromovements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the piezo-active sensing element to an OMT amplifier located on the individual's skin where the biosignal is amplified. The OMT amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician.
    Type: Application
    Filed: December 8, 2015
    Publication date: June 8, 2017
    Inventors: Michael M. Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen
  • Publication number: 20160095908
    Abstract: The invention provides methods for treating primary disorders of mood and affect, including depressive disorders, anxiety, and sleep disorders and CNS disorders comprising the administration of a neurotoxin.
    Type: Application
    Filed: December 11, 2015
    Publication date: April 7, 2016
    Inventors: Gary E. Borodic, Martin Acquadro
  • Publication number: 20060147471
    Abstract: Devices, methods and kits are disclosed for preparing and administering less-painful formulations of Botulinum toxin. The devices, methods and kits of the present invention are comprised of or use an acidic formulation of Botulinum toxin, or, in certain embodiments, a freeze- or flash-dried composition of Botulinum toxin, having a long shelf-life which is subsequently mixed with an acid-neutralizing solution and, optionally a sequestration agent prior to administration to a patient in need thereof. The pH-neutralized formulation of Botulinum toxin is pharmaceutically acceptable for administration to a patient and is significantly less painful than acidic formulations of Botulinum toxin or formulations of Botulinum toxin having unnecessary antigens.
    Type: Application
    Filed: February 1, 2005
    Publication date: July 6, 2006
    Inventors: Gary Borodic, Martin Acquadro