Patents by Inventor Martin Acquadro
Martin Acquadro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12329513Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.Type: GrantFiled: December 7, 2020Date of Patent: June 17, 2025Inventors: Michael Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen
-
Patent number: 12207936Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.Type: GrantFiled: January 11, 2021Date of Patent: January 28, 2025Assignee: BRAINSTEM BIOMETRICS, INC.Inventors: Michael Baltay, Bruce Rasmussen, Yahya Shehabi, Ciaran Bolger, Martin Acquadro, Clark B. Foster
-
Publication number: 20210236051Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.Type: ApplicationFiled: January 11, 2021Publication date: August 5, 2021Inventors: Michael Baltay, Bruce Rasmussen, Yahya Shehabi, Ciaran Bolger, Martin Acquadro, Clark B. Foster
-
Publication number: 20210113115Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.Type: ApplicationFiled: December 7, 2020Publication date: April 22, 2021Inventors: Michael Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen
-
Patent number: 10888268Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brainstem activity is provided. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient is also provided.Type: GrantFiled: December 8, 2016Date of Patent: January 12, 2021Inventors: Michael Baltay, Bruce Rasmussen, Yahya Shehabi, Ciaran Bolger, Martin Acquadro, Clark B. Foster
-
Patent number: 10856774Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.Type: GrantFiled: October 16, 2017Date of Patent: December 8, 2020Inventors: Michael M Baltay, Clark B Foster, Ciaran Bolger, Martin Acquadro, Bruce A Rasmussen
-
Publication number: 20180160968Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brainstem activity is provided. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient is also provided.Type: ApplicationFiled: December 8, 2016Publication date: June 14, 2018Inventors: Michael Baltay, Bruce Rasmussen, Yahya Shehabi, Ciaran Bolger, Martin Acquadro, Clark B. Foster
-
Publication number: 20180116558Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.Type: ApplicationFiled: October 16, 2017Publication date: May 3, 2018Inventors: Michael M. Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen
-
Patent number: 9788760Abstract: An ocular micro tremor (OMT) sensor, system and method for measuring micromovements of an individual's eyeball having an amplitude of 40 micrometers or less to provide a variable voltage biosignal for measuring the individual's brain stem activity. The OMT sensor includes a flexible piezo-active sensing element mounted at the individual's closed or opened eyelid so as to be deflected by the micromovements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the piezo-active sensing element to an OMT amplifier located on the individual's skin where the biosignal is amplified. The OMT amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician.Type: GrantFiled: December 8, 2015Date of Patent: October 17, 2017Inventors: Michael M Baltay, Clark B Foster, Ciaran Bolger, Martin Acquadro, Bruce A Rasmussen
-
Publication number: 20170156637Abstract: An ocular micro tremor (OMT) sensor, system and method for measuring micromovements of an individual's eyeball having an amplitude of 40 micrometers or less to provide a variable voltage biosignal for measuring the individual's brain stem activity. The OMT sensor includes a flexible piezo-active sensing element mounted at the individual's closed or opened eyelid so as to be deflected by the micromovements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the piezo-active sensing element to an OMT amplifier located on the individual's skin where the biosignal is amplified. The OMT amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician.Type: ApplicationFiled: December 8, 2015Publication date: June 8, 2017Inventors: Michael M. Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen
-
Publication number: 20160095908Abstract: The invention provides methods for treating primary disorders of mood and affect, including depressive disorders, anxiety, and sleep disorders and CNS disorders comprising the administration of a neurotoxin.Type: ApplicationFiled: December 11, 2015Publication date: April 7, 2016Inventors: Gary E. Borodic, Martin Acquadro
-
Publication number: 20060147471Abstract: Devices, methods and kits are disclosed for preparing and administering less-painful formulations of Botulinum toxin. The devices, methods and kits of the present invention are comprised of or use an acidic formulation of Botulinum toxin, or, in certain embodiments, a freeze- or flash-dried composition of Botulinum toxin, having a long shelf-life which is subsequently mixed with an acid-neutralizing solution and, optionally a sequestration agent prior to administration to a patient in need thereof. The pH-neutralized formulation of Botulinum toxin is pharmaceutically acceptable for administration to a patient and is significantly less painful than acidic formulations of Botulinum toxin or formulations of Botulinum toxin having unnecessary antigens.Type: ApplicationFiled: February 1, 2005Publication date: July 6, 2006Inventors: Gary Borodic, Martin Acquadro