Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: The invention is a light up toy with two or more lights manipulated by one or more strings to create patterns of light and light shows. The lights have covers to protect the lights from breaking and can protect the user or a bystander from the impact of the lights as well. The toy can be made with battery sections so that a dead battery can be changed and the toy can continue to be used with fresh batteries.

Abstract: An electronic toy with synchronized sound and lighting system that utilizes projectiles, and method, including a base, a projectile, pre-recorded sounds, a speaker, LED lights, and various circuitry. The invention can be programmed to operate in standby mode at all times, and will power-on when the user locks the projectile into the locking unit. The invention is programmed to initiate synchronized sequences of lights and sounds based on the user's locking and loading of a projectile into the invention, rather than through the use of unnecessary buttons or an on/off switch.

Abstract: The invention is a digital video camera and projector that is suitable for use by children or young adults, does not require the user to engage a mechanical switching of the lenses from video camera mode to Projection mode.

Abstract: A caged phosphine product is provided which can act as a ligand to form a metal complex. The metal complex can be used as a catalyst.

Abstract: The invention is a light up toy with two or more lights manipulated by one or more strings to create patterns of light and light shows. The lights have covers to protect the lights from breaking and can protect the user or a bystander from the impact of the lights as well. The toy can be made with battery sections so that a dead battery can be changed and the toy can continue to be used with fresh batteries.

Abstract: A head covering and insignia display assembly is structured in a sports helmet configuration and includes at least one insignia representative of a sports team. More in particular, the head covering assembly is constructed of a foldable material to facilitate transport and, additionally, the foldable material is structured to be weather resistant to at least partially protect the user from the elements, such as cold and/or precipitation. The head covering and insignia display assembly may include one or more auxiliary members such as, for example, a chin strap, a neckpiece, a face mask, and/or a visor. Further, an auxiliary accessory such as an audio or visual communication device and/or an illumination device may be incorporated in a cooperative and operational association with the head covering and insignia display assembly.

Abstract: An awning comprises an outer sheet of flexible material supported on a rigid translucent support. The awning is illuminated by strip lights mounted on a support framework, which is stepped back from the rigid translucent support. An even illumination is achieved with no shadow lines on the flexible sheet. The sheet may have advertising indicia or logos.

Abstract: Disclosed is a method of removing iodine-containing compounds from the reaction product of iodine-catalyzed acetoxylation, wherein an olefin is reacted with oxygen and a carboxylic acid, and the iodine is recycled to the reactor.

Abstract: A gas stream containing carbon monoxide and hydrogen is methanated by pasg the gas stream upwardly through a suspension of a finely divided hydrogenation catalyst in a fluidizing medium. The reaction takes place at a temperature of from 450 to 950.degree. F.