Abstract: The present invention relates to small-molecule inhibitors of the FRS2-FGFR interaction. The present invention relates the small-molecule inhibitors for use as a medicament and for use in cancer or metastasis treatment or prevention.

Abstract: The present invention relates to small-molecule inhibitors of the FRS2-FGFR interaction. The present invention relates the small-molecule inhibitors for use as a medicament and for use in cancer treatment or prevention.

Abstract: The invention is related to a device (1) for receiving a biological sample (3) wherein the device (1) comprises a plurality of wells (10) wherein each well (10) comprises an inner surface (14) facing a volume (60) for receiving a biological sample (3). The inner surface (14) comprises a top section (20) and a bottom section (30). The top section (20) and the bottom section (30) are connected via a circumferential step (40). The circumferential step (40) forms a stop for a tip of a pipette (70).

Abstract: The invention relates to a method for producing a sensor housing for a pressure sensor and to a sensor housing for a pressure sensor, to a pressure sensor having such a sensor housing, and to the use of an additive production device for producing such a sensor housing. A sensor body and/or at least one membrane stamp is applied to a provided metal plate by means of additive production. The additive production produces an integrally joined, in particular planar joint connection between the sensor body and/or the at least one membrane stamp, on the one side, and the metal plate, on the other side.

Abstract: The invention relates to a method for producing a sensor housing for a pressure sensor and to a sensor housing for a pressure sensor, to a pressure sensor having such a sensor housing, and to the use of an additive production device for producing such a sensor housing. A sensor body and/or at least one membrane stamp is applied to a provided metal plate by means of additive production. The additive production produces an integrally joined, in particular planar joint connection between the sensor body and/or the at least one membrane stamp, on the one side, and the metal plate, on the other side.

Abstract: A data communication method between a first communication user arranged at a motor vehicle and a second communication user arranged outside the motor vehicle is provided. The first communication user can be addressed by the second communication user by way of a network address. The network address of the first communication user is defined by an address management unit arranged outside the motor vehicle and is transmitted to the first communication user.

Abstract: A process is provided for transferring a first sequence control and/or first data into a first control device and a second sequence control and/or second data into a second control device in a motor vehicle. The transfer is carried out by way of a first data bus while using a first transmission protocol which has a data frame with a predetermined frame format or message format, and the transfer as a whole takes place by the transmission of a plurality of data frames. In a first step, by way of a first data frame, a portion of the first sequence control and/or of the first data is transmitted to the first control device. In a second step, by way of the second data frame, a portion of the second sequence control and/or of the second data is transmitted to the second control device.

Abstract: To render possible a high-quality, yet cost-effective provision suitable for mass production of a piezoelectric pressure transducer (1) with at least one piezoelectric measuring element (3, 3?, 3?) arranged on a housing base part (2), which measuring element is connected on the opposite side to a diaphragm (4), the measuring element (3, 3?, 3?) is fixed on an electrode sheet (5, 5?, 5?, 5??) or directly on the base part 2 or the diaphragm 4, wherein the electrode sheet (5, 5?, 5?, 5??) wraps conductively and positively as well as in a manner fixing the layers around a contact pin (7) insulated with respect to the base part (2) and projecting outwards.

Abstract: To render possible a high-quality, yet cost-effective provision suitable for mass production of a piezoelectric pressure transducer (1) with at least one piezoelectric measuring element (3, 3?, 3?) arranged on a housing base part (2), which measuring element is connected on the opposite side to a diaphragm (4), the measuring element (3, 3?, 3?) is fixed on an electrode sheet (5, 5?, 5?, 5??) or directly on the base part 2 or the diaphragm 4, wherein the electrode sheet (5, 5?, 5?, 5??) wraps conductively and positively as well as in a manner fixing the layers around a contact pin (7) insulated with respect to the base part (2) and projecting outwards.

Abstract: A process is provided for transferring a first sequence control and/or first data into a first control device and a second sequence control and/or second data into a second control device in a motor vehicle, which are each connected by way of a first data bus with a transmission device. The transmission device preferably is a vehicle-external transmission device. The transfer is carried out by way of the first data bus while using a first transmission protocol. The first transmission protocol has a data frame with a predetermined frame format or message format, and the transfer as a whole takes place by the transmission of a plurality of data frames. In order to rapidly transfer large quantities of data into the control devices of the vehicle, in a first step, by way of a first data frame, a portion of the first sequence control and/or of the first data is transmitted to the first control device.

Abstract: A data communication method between a first communication user arranged at a motor vehicle and a second communication user arranged outside the motor vehicle is provided. The first communication user can be addressed by the second communication user by way of a network address. The network address of the first communication user is defined by an address management unit arranged outside the motor vehicle and is transmitted to the first communication user.

Abstract: An optoelectronic measuring device for monitoring combustion processes in the combustion chamber of an internal combustion engine during operation includes optical sensors assigned to the combustion chamber and connected to an evaluation unit, the sensor ends on the side of the combustion chamber being essentially positioned in a plane and the sensors being aligned so that the individual viewing angles of the sensors will uniformly cover at least one predefined measuring sector of the combustion chamber. A simple way of localizing the origin of engine knocking in the combustion chamber is ensured by positioning the optical sensors in an essentially cylindrical component projecting into the combustion chamber with the sensor ends positioned essentially radially along the wall of the component.

Abstract: A process for preparing poly(vinyl acetals) or poly(vinyl ketals) by reacting poly(vinyl alcohol) with an aldehyde or ketone in the presence of a catalyst which contains acid groups which are chemically bound on a sheet-like support which is insoluble in the reaction medium.