Patents by Inventor Martin Biehl
Martin Biehl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11933787Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.Type: GrantFiled: December 16, 2022Date of Patent: March 19, 2024Assignee: MILTENYI BIOTEC B.V. & CO. KGInventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
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Publication number: 20240033183Abstract: A valve unit for a system for producing a medical preparation for parenteral nutrition is described. The valve unit includes a housing having a duct extending along a longitudinal access of housing, upper inlets and lower inlets, and an outlet in fluid communication with each of the inlets via the duct. The valve unit includes valves that alternately connect a respective upper inlet of the upper inlets and a respective lower inlet of the lower inlets to the duct. Each of the valves have a first passage that fluidly connects the respective upper inlet and the duct, and a second passage that fluidly connects the respective lower inlet and the duct.Type: ApplicationFiled: October 10, 2023Publication date: February 1, 2024Inventors: Martin Biehl, Michael Hock, Lothar Tiedemann, Klaus Buettner
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Patent number: 11793723Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. The installation comprises a pump with which liquids can be transferred from a plurality of source containers into a target container. The installation has a modular construction and comprises a weighing module and a main module with the pump. According to a further aspect of the invention, the pump is arranged at an inclination with respect to a vertical plane. According to a further aspect of the invention, the installation comprises cascaded valve nodes.Type: GrantFiled: May 10, 2021Date of Patent: October 24, 2023Assignee: Fresenius Kabi Deutschland GmbHInventors: Martin Biehl, Michael Hock, Henrik Schaake, Ulla Schöbel, Holger Lenkeit, Marcel Borgward
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Patent number: 11793722Abstract: The invention relates to a valve unit for a system for producing a parenteral nutrition, in which a three-way valve is used for respectively two connections to a source container. The valve unit is a component which is mounted on the system and can be removed again following use. The valve unit is in particular provided as a replaceable disposable component.Type: GrantFiled: August 22, 2018Date of Patent: October 24, 2023Assignee: Fresenius Kabi Deutschland GmbHInventors: Martin Biehl, Michael Hock, Lothar Tiedemann, Klaus Buettner
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Publication number: 20230176062Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.Type: ApplicationFiled: December 16, 2022Publication date: June 8, 2023Applicant: Miltenyi Biotec B.V. & Co. KGInventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
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Patent number: 11531031Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.Type: GrantFiled: April 20, 2022Date of Patent: December 20, 2022Assignee: MILTENYI BIOTEC GMBHInventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
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Patent number: 11499976Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.Type: GrantFiled: June 1, 2020Date of Patent: November 15, 2022Assignee: MILTENYI BIOTEC B.V. & CO. KGInventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
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Patent number: 11499977Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.Type: GrantFiled: April 20, 2022Date of Patent: November 15, 2022Assignee: MILTENYI BIOTEC B.V. & CO. KGInventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
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Publication number: 20220326248Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.Type: ApplicationFiled: April 20, 2022Publication date: October 13, 2022Applicant: MILTENYI BIOTEC B.V. & CO. KGInventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
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Publication number: 20220244264Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.Type: ApplicationFiled: April 20, 2022Publication date: August 4, 2022Applicant: MILTENYI BIOTEC B.V. & CO. KGInventors: Stefan Miltenyi, Winfried Schimmelpfenning, Holger Lantow, Niklas Eimar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
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Publication number: 20210369568Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. The installation comprises a pump with which liquids can be transferred from a plurality of source containers into a target container. The installation has a modular construction and comprises a weighing module and a main module with the pump. According to a further aspect of the invention, the pump is arranged at an inclination with respect to a vertical plane. According to a further aspect of the invention, the installation comprises cascaded valve nodes.Type: ApplicationFiled: May 10, 2021Publication date: December 2, 2021Inventors: Martin Biehl, Michael Hock, Henrik Schaake, Ulla Schöbel, Holger Lenkeit, Marcel Borgward
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Patent number: 11090479Abstract: The invention relates to a valve unit for a system for producing parenteral nutrition, in which unit a three-way valve is used for each pair of connections to a source container. The valve unit is a component that can be mounted on die system and removed again after use. The valve unit is in particular provided as an interchangeable disposable component.Type: GrantFiled: February 17, 2017Date of Patent: August 17, 2021Assignee: Fresenius Kabi Deutschland GmbHInventors: Martin Biehl, Michael Hock, Henrik Schaake, Marcel Borgward
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Patent number: 11077023Abstract: The invention relates to a method and a system for synthesizing a medical preparation, a peristaltic pump being used for pumping liquid from a plurality of source containers. According to the invention, micro-amounts are extracted only in the linear region of the peristaltic pump.Type: GrantFiled: March 15, 2017Date of Patent: August 3, 2021Assignee: Fresenius Kabi Deutschland GmbHInventors: Martin Biehl, Michael Hock, Henrik Schaake, Martin Bohm, Ulla Schöbel
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Patent number: 11045393Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. Liquids are transferred by means of the installation from a plurality of source containers to a target container. The installation comprises a receptacle with drivers for a valve block, wherein the drivers of the valves are arranged offset from one another.Type: GrantFiled: February 17, 2017Date of Patent: June 29, 2021Assignee: Fresenius Kabi Deutschland GmbHInventors: Martin Biehl, Michael Hock, Henrik Schaake, Stephan Gabriel, Martin Baecke
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Patent number: 11013666Abstract: The invention relates to a set of scales and to an installation for producing a medical composition using a set of scales. The set of scales comprise interchangeable securing means for a target container, the weight thereof being measured by the set of scales.Type: GrantFiled: March 15, 2017Date of Patent: May 25, 2021Assignee: Fresenius Kabi Deutschland GmbHInventors: Martin Biehl, Michael Hock, Ulla Schöbel, Marcel Borgward, Holger Lenkeit, Dirk Lamprecht, Sebastian Maier
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Patent number: 11000451Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. The installation comprises a pump with which liquids can be transferred from a plurality of source containers into a target container. The installation has a modular construction and comprises a weighing module and a main module with the pump. According to a further aspect of the invention, the pump is arranged at an inclination with respect to a vertical plane. According to a further aspect of the invention, the installation comprises cascaded valve nodes.Type: GrantFiled: March 15, 2017Date of Patent: May 11, 2021Assignee: Fresenius Kabi Deutchland GmbHInventors: Martin Biehl, Michael Hock, Henrik Schaake, Ulla Schöbel, Holger Lenkeit, Marcel Borgward
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Patent number: 10966906Abstract: The invention relates to a method and a system for synthesizing a medical preparation, a peristaltic pump being used for pumping liquid from a plurality of source containers. According to the invention, the individual metering steps are verified by a weighing process, even the metering of micro-amounts being verifiable.Type: GrantFiled: March 15, 2017Date of Patent: April 6, 2021Assignee: Fresenius Kabi Deutschland GmbHInventors: Martin Biehl, Michael Hock, Henrik Schaake, Ulla Schöbel, Martin Bohm
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Publication number: 20200306139Abstract: The invention relates to a valve unit for a system for producing a parenteral nutrition, in which a three-way valve is used for respectively two connections to a source container. The valve unit is a component which is mounted on the system and can be removed again following use. The valve unit is in particular provided as a replaceable disposable component.Type: ApplicationFiled: August 22, 2018Publication date: October 1, 2020Inventors: Martin Biehl, Michael Hock, Lothar Tiedemann, Klaus Buettner
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Publication number: 20200292552Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.Type: ApplicationFiled: June 1, 2020Publication date: September 17, 2020Applicant: MILTENYI BIOTEC B.V. & CO. KGInventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
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Publication number: 20200289372Abstract: The invention relates to a method and a system for synthesizing a medical preparation, a peristaltic pump being used for pumping liquid from a plurality of source containers. According to the invention, micro-amounts are extracted only in the linear region of the peristaltic pump.Type: ApplicationFiled: March 15, 2017Publication date: September 17, 2020Inventors: Martin Biehl, Michael HOCK, Henrik SCHAAKE, Martin BOHM, Ulla SCHÕBEL