Patents by Inventor Martin Biehl

Martin Biehl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11933787
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: March 19, 2024
    Assignee: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
  • Publication number: 20240033183
    Abstract: A valve unit for a system for producing a medical preparation for parenteral nutrition is described. The valve unit includes a housing having a duct extending along a longitudinal access of housing, upper inlets and lower inlets, and an outlet in fluid communication with each of the inlets via the duct. The valve unit includes valves that alternately connect a respective upper inlet of the upper inlets and a respective lower inlet of the lower inlets to the duct. Each of the valves have a first passage that fluidly connects the respective upper inlet and the duct, and a second passage that fluidly connects the respective lower inlet and the duct.
    Type: Application
    Filed: October 10, 2023
    Publication date: February 1, 2024
    Inventors: Martin Biehl, Michael Hock, Lothar Tiedemann, Klaus Buettner
  • Patent number: 11793723
    Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. The installation comprises a pump with which liquids can be transferred from a plurality of source containers into a target container. The installation has a modular construction and comprises a weighing module and a main module with the pump. According to a further aspect of the invention, the pump is arranged at an inclination with respect to a vertical plane. According to a further aspect of the invention, the installation comprises cascaded valve nodes.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: October 24, 2023
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Martin Biehl, Michael Hock, Henrik Schaake, Ulla Schöbel, Holger Lenkeit, Marcel Borgward
  • Patent number: 11793722
    Abstract: The invention relates to a valve unit for a system for producing a parenteral nutrition, in which a three-way valve is used for respectively two connections to a source container. The valve unit is a component which is mounted on the system and can be removed again following use. The valve unit is in particular provided as a replaceable disposable component.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: October 24, 2023
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Martin Biehl, Michael Hock, Lothar Tiedemann, Klaus Buettner
  • Publication number: 20230176062
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Application
    Filed: December 16, 2022
    Publication date: June 8, 2023
    Applicant: Miltenyi Biotec B.V. & Co. KG
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
  • Patent number: 11531031
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Grant
    Filed: April 20, 2022
    Date of Patent: December 20, 2022
    Assignee: MILTENYI BIOTEC GMBH
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
  • Patent number: 11499976
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: November 15, 2022
    Assignee: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
  • Patent number: 11499977
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Grant
    Filed: April 20, 2022
    Date of Patent: November 15, 2022
    Assignee: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
  • Publication number: 20220326248
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Application
    Filed: April 20, 2022
    Publication date: October 13, 2022
    Applicant: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
  • Publication number: 20220244264
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Application
    Filed: April 20, 2022
    Publication date: August 4, 2022
    Applicant: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Stefan Miltenyi, Winfried Schimmelpfenning, Holger Lantow, Niklas Eimar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
  • Publication number: 20210369568
    Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. The installation comprises a pump with which liquids can be transferred from a plurality of source containers into a target container. The installation has a modular construction and comprises a weighing module and a main module with the pump. According to a further aspect of the invention, the pump is arranged at an inclination with respect to a vertical plane. According to a further aspect of the invention, the installation comprises cascaded valve nodes.
    Type: Application
    Filed: May 10, 2021
    Publication date: December 2, 2021
    Inventors: Martin Biehl, Michael Hock, Henrik Schaake, Ulla Schöbel, Holger Lenkeit, Marcel Borgward
  • Patent number: 11090479
    Abstract: The invention relates to a valve unit for a system for producing parenteral nutrition, in which unit a three-way valve is used for each pair of connections to a source container. The valve unit is a component that can be mounted on die system and removed again after use. The valve unit is in particular provided as an interchangeable disposable component.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: August 17, 2021
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Martin Biehl, Michael Hock, Henrik Schaake, Marcel Borgward
  • Patent number: 11077023
    Abstract: The invention relates to a method and a system for synthesizing a medical preparation, a peristaltic pump being used for pumping liquid from a plurality of source containers. According to the invention, micro-amounts are extracted only in the linear region of the peristaltic pump.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: August 3, 2021
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Martin Biehl, Michael Hock, Henrik Schaake, Martin Bohm, Ulla Schöbel
  • Patent number: 11045393
    Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. Liquids are transferred by means of the installation from a plurality of source containers to a target container. The installation comprises a receptacle with drivers for a valve block, wherein the drivers of the valves are arranged offset from one another.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: June 29, 2021
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Martin Biehl, Michael Hock, Henrik Schaake, Stephan Gabriel, Martin Baecke
  • Patent number: 11013666
    Abstract: The invention relates to a set of scales and to an installation for producing a medical composition using a set of scales. The set of scales comprise interchangeable securing means for a target container, the weight thereof being measured by the set of scales.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: May 25, 2021
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Martin Biehl, Michael Hock, Ulla Schöbel, Marcel Borgward, Holger Lenkeit, Dirk Lamprecht, Sebastian Maier
  • Patent number: 11000451
    Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. The installation comprises a pump with which liquids can be transferred from a plurality of source containers into a target container. The installation has a modular construction and comprises a weighing module and a main module with the pump. According to a further aspect of the invention, the pump is arranged at an inclination with respect to a vertical plane. According to a further aspect of the invention, the installation comprises cascaded valve nodes.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: May 11, 2021
    Assignee: Fresenius Kabi Deutchland GmbH
    Inventors: Martin Biehl, Michael Hock, Henrik Schaake, Ulla Schöbel, Holger Lenkeit, Marcel Borgward
  • Patent number: 10966906
    Abstract: The invention relates to a method and a system for synthesizing a medical preparation, a peristaltic pump being used for pumping liquid from a plurality of source containers. According to the invention, the individual metering steps are verified by a weighing process, even the metering of micro-amounts being verifiable.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: April 6, 2021
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Martin Biehl, Michael Hock, Henrik Schaake, Ulla Schöbel, Martin Bohm
  • Publication number: 20200306139
    Abstract: The invention relates to a valve unit for a system for producing a parenteral nutrition, in which a three-way valve is used for respectively two connections to a source container. The valve unit is a component which is mounted on the system and can be removed again following use. The valve unit is in particular provided as a replaceable disposable component.
    Type: Application
    Filed: August 22, 2018
    Publication date: October 1, 2020
    Inventors: Martin Biehl, Michael Hock, Lothar Tiedemann, Klaus Buettner
  • Publication number: 20200292552
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Application
    Filed: June 1, 2020
    Publication date: September 17, 2020
    Applicant: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschaefer, Martin Biehl, Eiad Kabaha, Juergen Schulz
  • Publication number: 20200289372
    Abstract: The invention relates to a method and a system for synthesizing a medical preparation, a peristaltic pump being used for pumping liquid from a plurality of source containers. According to the invention, micro-amounts are extracted only in the linear region of the peristaltic pump.
    Type: Application
    Filed: March 15, 2017
    Publication date: September 17, 2020
    Inventors: Martin Biehl, Michael HOCK, Henrik SCHAAKE, Martin BOHM, Ulla SCHÕBEL