Abstract: The present invention relates to a crescent or tri-corner shaped orthopedic plate with at least a first and a second end, and generally coextensive top and bottom surfaces joined directly or indirectly by an edge. The plate includes a plurality of fixation holes the first end of the plate and a second end of the plate that receives locking screws and intermediate the two holes, the plate includes a recess that defines a screw hole edge at an angle relative to the top surface of the plate so as to receive and support a screw in the recess. The invention further relates to a method of fusion using the plate and a clamp designed for the method.

Abstract: A four corner fusion system can include a curved plate that is more aligned with the natural anatomy of the wrist joint, and/or fewer number of screws (for example, about three or four screws). The system can have a lower profile, resulting in less soft tissue impingement. A surgical tool with a pair of offsetting clamping arms can be used to aid in bone reduction during a wrist fusion procedure.

Abstract: The present invention relates to a crescent or tri-corner shaped orthopedic plate with at least a first and a second end, and generally coextensive top and bottom surfaces joined directly or indirectly by an edge. The plate includes a plurality of fixation holes the first end of the plate and a second end of the plate that receives locking screws and intermediate the two holes, the plate includes a recess that defines a screw hole edge at an angle relative to the top surface of the plate so as to receive and support a screw in the recess. The invention further relates to a method of fusion using the plate and a clamp designed for the method.

Abstract: The present invention relates to a crescent or tri-corner shaped orthopedic plate with at least a first and a second end, and generally coextensive top and bottom surfaces joined directly or indirectly by an edge. The plate includes a plurality of fixation holes the first end of the plate and a second end of the plate that receives locking screws and intermediate the two holes, the plate includes a recess that defines a screw hole edge at an angle relative to the top surface of the plate so as to receive and support a screw in the recess. The invention further relates to a method of fusion using the plate and a clamp designed for the method.

Abstract: The present invention relates to a crescent or tri-corner shaped orthopedic plate with at least a first and a second end, and generally coextensive top and bottom surfaces joined directly or indirectly by an edge. The plate includes a plurality of fixation holes the first end of the plate and a second end of the plate that receives locking screws and intermediate the two holes, the plate includes a recess that defines a screw hole edge at an angle relative to the top surface of the plate so as to receive and support a screw in the recess. The invention further relates to a method of fusion using the plate and a clamp designed for the method.

Abstract: Group B streptococcus (GBS) proteins and polynucleotides encoding them are disclosed. Said proteins are antigenic and therefore useful vaccine components for the prophylaxis or therapy of streptococcus infection in animals. Also disclosed are recombinant methods of producing the protein antigens as well as diagnostic assays for detecting streptococcus bacterial infection.

Abstract: Group B streptococcus (GBS) proteins and polynucleotides encoding them are disclosed. Said proteins are antigenic and therefore useful vaccine components for the prophylaxis or therapy of streptococcus infection in animals. Also disclosed are recombinant methods of producing the protein antigens as well as diagnostic assays for detecting streptococcus bacterial infection.

Abstract: Fusion proteins comprising an antigen derived from NY-ESO-1 linked to an antigen derived from LAGE-1, which may further comprise carriers, fusion partners, or the like, are provided. Methods for preparing, formulating, and using such fusion proteins are also provided. Such proteins are useful a vaccine components for inducing an immune response against a range of cancer-antigen-bearing cells.

Abstract: Group B streptococcus (GBS) proteins and polynucleotides encoding them are disclosed. Said proteins are antigenic and therefore useful vaccine components for the prophylaxis or therapy of streptococcus infection in animals. Also disclosed are recombinant methods of producing the protein antigens as well as diagnostic assays for detecting streptococcus bacterial infection.

Abstract: Group B streptococcus (GBS) proteins and polynucleotides encoding them are disclosed. Said proteins are antigenic and therefore useful vaccine components for the prophylaxis or therapy of streptococcus infection in animals. Also disclosed are recombinant methods of producing the protein antigens as well as diagnostic assays for detecting streptococcus bacterial infection.

Abstract: Group B streptococcus (GBS) proteins and polynucleotides encoding them are disclosed. Said proteins are antigenic and therefore useful vaccine components for the prophylaxis or therapy of streptococcus infection in animals. Also disclosed are recombinant methods of producing the protein antigens as well as diagnostic assays for detecting streptococcus bacterial infection.

Abstract: The present invention relates to antigens, more particularly an antigen of Streptococcus pyogenes (also called group A Streptococcus (GAS)) bacterial pathogen which is useful as vaccine component for therapy and/or prophylaxis.

Abstract: The present invention relates to antigens, more particularly antigens of Group B Streptococcus (GBS) (S. agalactiae) which may be useful to prevent, diagnose and/or treat streptococcal infections.

Abstract: Fusion proteins comprising an antigen derived from NY-ESO-1 linked to an antigen derived from LAGE-1, which may further comprise carriers, fusion partners, or the like, are provided. Methods for preparing, formulating, and using such fusion proteins are also provided. Such proteins are useful a vaccine components for inducing an immune response against a range of cancer-antigen-bearing cells.

Abstract: The present invention relates to antigens, more particularly antigens of Group B Streptococcus (GBS) (S. agalactiae) which may be useful to prevent, diagnose and/or treat streptococcal infections.

Abstract: Group B Streptococcus polypeptides and polynucleotides encoding them are disclosed. Said polypeptides may be useful for the prophylaxis, diagnostic and/or therapy of streptococcal infection in mammals. Also disclosed are recombinant methods of producing the polypeptide antigens as well as diagnostic assays for detecting streptococcal infections, particularly GBS.

Abstract: The present invention relates to antigens, more particularly antigens of Group B Streptococcus (GBS) (S. agalactiae) which may be useful to prevent, diagnose and/or treat streptococcal infections.

Abstract: Group B streptococcus polypeptides and polynucleotides encoding them are disclosed. Said polypeptides may be useful for the prophylaxis, diagnostic and/or therapy of streptococcal infection in mammals. Also disclosed are recombinant methods of producing the polypeptide antigens as well as diagnostic assays for detecting streptococcal infections, particularly GBS.

Abstract: The present invention relates to antigens, more particularly an antigen of Streptococcus pyogenes (also called group A Streptococcus (GAS)) bacterial pathogen which is useful as vaccine component for therapy and/or prophylaxis.

Abstract: The present invention relates to antigens, more particularly an antigen of Streptococcus pygenes (also called group A Streptococcus (GAS)) bacterial pathogen which is useful as vaccine component for therapy and/or prophylaxis.