Abstract: A sachet (10) for containing solid tablets (30) having a cavity (11) with an outlet tunnel (20) a long which a tablet (30) can be moved in an outward direction, the outlet tunnel (20) comprising sequential sections (20A, 20B) in the outward direction aligned at a non-180° angle to each other, and the cavity (20) contains at least one solid tablet (30) which can be urged into the inlet opening (21), along the outlet tunnel and out through the outlet opening (22). The angled sections of the outlet tunnel impart child-resistance to the sachet.

Abstract: A sachet (10) for containing solid tablets (30) having a cavity (11) with an outlet tunnel (20) a long which a tablet (30) can be moved in an outward direction, the outlet tunnel (20) comprising sequential sections (20A, 20B) in the outward direction aligned at a non-180° angle to each other, and the cavity (20) contains at least one solid tablet (30) which can be urged into the inlet opening (21), along the outlet tunnel and out through the outlet opening (22). The angled sections of the outlet tunnel impart child-resistance to the sachet.

Abstract: A low profile scoop for dosing of powdered infant formula has a handle portion and a bowl with an open mouth and a closed underside. The bowl has a width that is relatively smaller than both its length and its depth, allowing it to be placed on its side in areas of relatively low head space. The scoop may be used in package for powdered infant nutrition including a tub defining a product containing space and a lid having limited head space.

Abstract: An inhaler (1) for dispensing doses of medicament from a container under user activation includes a body (7) which includes a mouthpiece (5) through which the medicament is dispensed and a cap (2) which can be place in a position to substantially occlude the mouthpiece (5). The cap (2) is attached to the body (7) by a strap (3) which pivots from the body (7), the cap (2) being arranged to slide on the strap (3) such that the cap (2) must translate away from the mouthpiece (5) prior to the pivoting of the strap (3).

Abstract: The protein NM23 is disclosed as an agent for the maintenance of undifferentiated biological cells in culture. The NM23 protein may act as a survival factor for such cultured cells, or to prevent the differentiation and maturation of the cultured cells. The use of NM23 protein is applicable to culture of stem and/or progenitor cells, and particularly to such cells cultured and adapted for therapeutic use. The invention provides methods, media and media supplements for use in the culture of biological cells, and further provides methods of preparing biological cells for therapeutic use, as well as methods of therapy utilising biological cells and medicaments comprising biological cells adapted for therapeutic use.

Abstract: An inhaler (1) for dispensing doses of medicament from a container under user activation said inhaling which comprises a body (7) which includes a mouthpiece (5) through which the medicament is dispensed and a cap (2) which can be place in a position to substantially occlude the mouthpiece (5). The cap (2) is attached to said body (7) by a strap (3) which pivots from said body (7), said cap (2) being arranged to slide on the strap (3) such that the cap (2) must translate away from the mouthpiece (5) prior to the pivoting of the strap (3).

Abstract: A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body and a cartridge with one or more compartments each containing one dose of a drug. The compartment has holes to admit air and holes to deliver powder, which, in use, communicate with an inhalation channel in the inhaler body. To prevent the powder from leaking through the compartment holes before use, the air admission holes are of reduced dimension, thereby blocking or hindering powder exit under the force of gravity. When the cartridge is inserted inside the inhaler body, all its holes can be blocked. By sliding the cartridge in relation to the body until the inhalation position is reached, the holes come into in fluid communication with one another and with the inhalation channel, thereby allowing a flow of air to disperse and entrain the dose through the mouthpiece. Five embodiments are disclosed.

Abstract: A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body and a cartridge with one or more compartments each containing one dose of a drug. The compartment has holes to admit air and holes to deliver powder, which, in use, communicate with an inhalation channel in the inhaler body. To prevent the powder from leaking through the compartment holes before use, the air admission holes are of reduced dimension, thereby blocking or hindering powder exit under the force of gravity. When the cartridge is inserted inside the inhaler body, all its holes can be blocked. By sliding the cartridge in relation to the body until the inhalation position is reached, the holes come into in fluid communication with one another and with the inhalation channel, thereby allowing a flow of air to disperse and entrain the dose through the mouthpiece. Five embodiments are disclosed.

Abstract: Inhaler device counter (20) for displaying the number of remaining doses in an inhaler device (10). The counter (20) comprises a counter mechanism and a display arrangement (60), wherein the display arrangement (60) is of pointer-gauge type with a static display section (90) provided as an integrated part of a transparent display containing part (150, 300) of a counter housing (70). There is also provided a method.

Abstract: An inhaler (1) for dispensing doses of medicament from a container under user activation said inhaling which comprises a body (7) which includes a mouthpiece (5) through which the medicament is dispensed and a cap (2) which can be place in a position to substantially occlude the mouthpiece (5). The cap (2) is attached to said body (7) by a strap (3) which pivots from said body (7), said cap (2) being arranged to slide on the strap (3) such that the cap (2) must translate away from the mouthpiece (5) prior to the pivoting of the strap (3).