Abstract: A dressing for wounds includes a useful material, such as dye or biocide, trapped within or behind a gelatin barrier. On application to a wound, metalloproteinases naturally present in the wound diffuse into the dressing and degrade the gelatin, releasing the trapped material. The released material serves various useful purposes, such as indicating the status of the wound or improving wound healing.

Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, including at least one colored microsphere which has a color characteristic; producing a magnified optical image of individual microspheres of the microarray; locating a microsphere in the aperture of a spectrometer to confine the color region of interest of the located microsphere in order to determine one or more color characteristics thereof; and determining one or more color characteristics of the located microsphere by means of the spectrometer.

Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, at least one of which has a color characteristic; capturing the microarray with an electronic color image sensor assembly having a matrix of pixels to produce an electronic microarray image; detecting the location of a microsphere within the captured microarray image; and identifying a color characteristic of the detected microsphere.

Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, including at least one colored microsphere which has a color characteristic; producing a magnified optical image of individual microspheres of the microarray; locating a microsphere in the aperture of a spectrometer to confine the color region of interest of the located microsphere in order to determine one or more color characteristics thereof; and determining one or more color characteristics of the located microsphere by means of the spectrometer.

Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, at least one of which has a color characteristic; capturing the microarray with an electronic color image sensor assembly having a matrix of pixels to produce an electronic microarray image; detecting the location of a microsphere within the captured microarray image; and identifying a color characteristic of the detected microsphere.

Abstract: The invention discloses an apparatus for compensation for spectral fluctuation of a light source. Additionally the invention discloses a scanner incorporating the apparatus for compensation. A lamp generates light, which is sent into a light directing device. From the light directing device a sensor means and a spectral monitor means for determining the spectral content of the light from said lamp receive the light. A signal processing means receives the output from said spectral monitor means and said sensor means for producing a signal compensated for spectral fluctuations. A scanner, incorporating the inventive apparatus, additionally comprises a medium for scanning which is positioned between said sensor means and said light directing device and a lens is positioned between said medium for scanning and said sensor means, for imaging said medium onto said sensor means.

Abstract: An image sensing device having an array of photodetectors capable of generating electron/hole pairs from incident photons, with multiple charge coupled devices organized in a tandem well design that employs multiple storage wells per pixel. The wells use thresholds to control the overflow of charge from one well to the next and are arranged such that a first charge coupled device having a plurality of cells is operatively coupled to the photodetectors by first transfer means for placing charge accumulated within the photodetectors from generated electron/hole pairs within the first charge coupled device, and a second charge coupled device having a plurality of cells being operatively coupled to the first charge coupled device by second transfer means for removing charge exceeding a predetermined threshold within the first charge coupled device and placing charge exceeding the predetermined threshold within the second charge coupled device.

Abstract: The method of the present invention reduces noise in digital photographic images by decomposing the digital image into smooth regions and edge regions and by electronically blurring the smooth regions. Smooth regions are areas lacking any sharp detail, such as blue sky. Edge regions are regions containing sharp detail, such as grass. The method operates by choosing a set of neighborhood pixel types from a matrix of pixels representing an image. For each target pixel in the image, all neighborhoods that include the target pixel are considered and a linear least squares regression is computed to fit a plane to the code values of the pixels in each neighborhood, resulting in a goodness of fit and least squares estimate for the code value at the target pixel. Finally, a noise reduced code value for the target pixel is computed as a normalized, weighted sum of the least squares estimates for the target pixel, summed over all the neighborhoods containing the target pixel.

Abstract: A linear light source includes: a lamp for producing a beam of light; a cylindrical integrating cavity having an entry port for introducing the beam of light into the cylindrical integrating cavity and a linear slot parallel to the cylindrical axis of the integrating cavity for emitting a line of diffuse light that is uniform over an angular range; and an optical element aligned with the slot for reducing the angular divergence of the light exiting from the slot.

Abstract: The present invention reduces noise in digital photographic images based on the assumption that images may be decomposed into two types of regions, smooth regions and edge regions. Smooth regions are areas of the image lacking any sharp detail, such as blue sky. Edge regions are regions containing sharp detail, such as edges and textured regions (such as grass). The present method reduces noise in the smooth regions by a mathematical blurring technique based on least squares regression. The blurring does not degrade the sharpness of the image, because there are no sharp details in the smooth regions. Edge regions are left undisturbed to maintain sharpness, but the noise is less noticeable in those regions than in the smooth regions. The method operates upon the luminance and chrominance component of a digital image.

Abstract: A moving mask is incorporated in a flying spot scanner to reduce flare. The mask obscures all portions of the object being scanned, except for a small region surrounding the point currently being scanned. The mask moves to maintain registration with the flying spot. A rotating slotted disk with curved slots in cooperation with a fixed mask having a slot is described as one mechanism for achieving such masking.

Abstract: A highly uniform infrared illumination source for illuminating a stripe of a moving sensitized web for line scan imaging of imperfections in the coating on the web by a CCD imaging camera. A light integrator having an elongated housing formed with side and end walls defines a linear light integrating cavity having diffusely reflecting interior wall surfaces. An elongated array of infrared LEDs is spaced along the side wall for emitting light into the cavity for integration within the cavity. A longitudinally extending slit is formed in the side wall through which a diffuse, linear light beam exits the elongated slit having a varying longitudinal intensity profile. The intensity of the light emitted by the LEDs is modulated in an intensity pattern that alters the varying longitudinal intensity profile of the linear light beam to provide a desired longitudinal intensity profile of the stripe of diffuse illumination.

Abstract: The method of the present invention reduces noise in digital photographic images by decomposing the digital image into smooth regions and edge regions and by electronically blurring the smooth regions. Smooth regions are areas lacking any sharp detail, such as blue sky. Edge regions are regions containing sharp detail, such as grass. The method operates by choosing a set of neighborhood pixel types from a matrix of pixels representing an image. For each target pixel in the image, all neighborhoods that include the target pixel are considered and a linear least squares regression is computed to fit a plane to the code values of the pixels in each neighborhood, resulting in a goodness of fit and a least squares estimate for the code value at the target pixel. Finally, a noise reduced code value for the target pixel is computed as a normalized, weighted sum of the least squares estimates for the target pixel, summed over all the neighborhoods containing the target pixel.

Abstract: A linear light source for a film scanner includes an elongated light integrating cavity, formed within a light integrator, having diffusely reflective walls. Light is introduced into the cavity through an input port, and an output scan line of diffuse light is produced through an exit slit which is generally parallel to the longitudinal axis of the integrating cavity. The scan line of light is directed on film to be scanned in a stripe of illumination. The scan line of the illuminated film stripe is imaged onto a tri-linear CCD array for conversion of color intensity modulated pixels into scan line data sets. The linear light beam is reflected from a source region within the integrating cavity visible through the exit slit. In order to make the brightness profile of the linear light beam more uniform and avoid position dependent signal level drop outs, sharp angle joints in the source region are replaced by arcuate sections.

Abstract: An elongated light source of the type employed in a document scanner for forming a line of uniform intensity, diffuse illumination at a document scanning plane. The light source has a longitudinally extending aperture for generating a line of light aligned with the light entrance end face of a generally planar, light conducting pipe. The light conducting pipe conducts light through its length and emits the light at a light exiting end face in proximity to a document scanning plane. The emitted light is spectrally filtered within the light pipe by the selected colored material thereof for absorbing unwanted wavelengths and/or by shaping the light pipe and/or by use of dichroic filter coatings for reflecting unwanted light wavelengths.

Abstract: A linear light source for a film scanner is disclosed which includes an elongated light integrating cavity, formed within a solid illumination body, having diffusely reflective walls. Light is introduced into the cavity through an input port, and an output beam of diffuse light is produced through a slot which is generally parallel to the longitudinal axis of the integrating cavity. In order to increase the efficiency of the light source, light is introduced into the cavity through a high collection non-imaging optical device formed as a hollow bore within the illumination body.

Abstract: An improved linear light source or light collector for a film scanner comprising an elongated, cylindrical light integrating cylinder enclosed by first and second end walls and a longitudinal, cylindrical side wall, all having a diffusely-reflecting interior surface, the longitudinal side wall having a longitudinally extending outlet/inlet slit therein and an elongated light pipe, e.g. a glass rod, having a port at one end thereof for emitting light entering its input port (when used as a source) or for collecting light entering the slit (when used as a collector) in a preferred intensity profile varying along its length. The glass rod is mounted inside and parallel to the side wall of the cavity to direct light emitted laterally therefrom toward or to collect light reflected from the diffusely-reflecting interior surfaces. When used as a light source, a lens system directs the light from the light source into the end port of the glass rod.

Abstract: Film contact scanners are provided which irradiate a first surface of a film with a light source, and receive an image of the film from a second side of the film at an array of photosensors. In a first embodiment, the array of photosensors is disposed adjacent the film so that each photosensor receives light from a separate point on the film. In a second embodiment, a bundle of optical fibers is disposed between the film and the array of photosensors. A gap is provided between the film and a first end of the bundle of optical fibers. Each photosensor receives the light from one or more of optical fibers for producing a predetermined MTF. In the second embodiment, a portion of the film between the light source and the bundle of optical fibers is formed in a cylindrical shape. A linear direction of the cylindrical shape is oriented to permit the photosensors to scan the film in a first direction.

Abstract: An improved linear light source or light collector for a film scanner comprising an elongated, solid, light integrating, light conducting rod having an axial port at one end thereof through which a light beam is introduced into or directed out of the rod and an output/input strip extending generally parallel to its longitudinal axis. The rod preferably comprises a core of transparent glass having a first index of refraction with a cladding layer covering the core, except in a first elongated strip, of a glass having a second index of refraction. A coating of diffusely reflective paint is applied over the cladding and the first elongated strip, except in a second elongated strip (which defines the output/input strip), wherein the first and second elongated strips do not overlap one another.

Abstract: An integrating cylinder for use as an illuminator for a film scanner includes a hollow cylinder including an inner surface defining a cavity therein and an outer surface, a diffusing layer of reflective material covering an inner surface of the hollow cylinder, a first end plate for sealing a near end of the hollow cylinder, and a second end plate for sealing a far end of the hollow cylinder opposite the near end. The hollow cylinder defines a slit formed parallel to a longitudinal axis of the hollow cylinder between the inner and outer surfaces at a predetermined line along a circumference of the hollow cylinder. The first end plate defines a hole which is decentered from the longitudinal axis of the hollow cylinder and can be tilted at a predetermined angle to the longitudinal axis of the hollow cylinder towards an area of the inner surface of the hollow cylinder.