Patents by Inventor Martin C. N. M. Barnardo

Martin C. N. M. Barnardo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method
    Patent number: 8609436
    Abstract: The invention provides a method of detecting the presence of anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and detecting the binding or absence of binding of antibodies to said recombinant MHC molecules. This method allows the detection and/or identification of one or more specific MHC particularly HLA allele antibodies.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: December 17, 2013
    Assignees: Guy's & St Thomas' Hospital NHS Trust (“GST”), King's College London, Oxford Radcliffe Hospital NHS (“ORH”) Trust of the John Radcliffe Hospital
    Inventors: Martin C. N. M. Barnardo, Andrea W. Harmer, Michael Bunce, Robert W. Vaughn, Kenneth I. Welsh
  • Method of producing a body fluid sample depleted of anti-MHC antibodies
    Patent number: 8088586
    Abstract: The invention provides a method of depleting anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and removing at least the recombinant MHC molecules to which antibodies to said recombinant MHC molecules contained within the sample have bound. This method allows the depletion of one or more specific MHC particularly HLA allele antibodies from a sample.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: January 3, 2012
    Assignees: Oxford Radcliffe Hospital NHS Trust, Guy's & St. Thomas' Hospital NHS Trust, King's College London
    Inventors: Martin C. N. M. Barnardo, Andrea W. Harmer, Michael Bunce, Robert W. Vaughan, Kenneth I. Welsh