Abstract: A headwear with a detachable visor is disclosed comprising a visor portion that is detachably attached to a crown portion. The visor portion is interchangeable or replaceable with a lip portion of the visor via at least two attachment members. The attachment members comprise a first attachment member secured to the front inner circumferential periphery of the crown portion and a second attachment member secured to the anterior portion of the lip portion of the visor. The attachment member includes a polymagnet, specifically neodymium magnets. Further, each of the attachment members comprises a first and second frame, made up of a thermoplastic polyurethane material and attached to the crown and visor via stitching or adhesive.

Abstract: The present disclosure relates to the area of automatic data generation, in particular data synthesis, defining a highly scalable methodology for data synthesis. The disclosure comprises a computer implemented method for training a model comprising plurality of data synthesizers for data synthesis. The method may in turn comprise: providing a dataset X of M columns and N rows, segmenting the N rows into segments of N/n rows, and slicing the M columns into slices of M/m columns, combining each segment with a corresponding slice, thereby providing a providing a plurality of blocks, each block comprising a combination of a segment with a slice, providing a model with K data synthesizers, training each data synthesizer with a corresponding block, wherein a transformation is performed to provide statistical independence between rows and/or statistical independency between columns of the dataset X. This method provides a substantially faster methodology, enabling a higher scalability.

Abstract: A kit for implanting a flexible multi-lead cardiac monitor for recording biosignals when the monitor is placed under the skin. The kit includes the monitor, an implantation tool for implanting the monitor under the skin, and optionally a surgical knife. The monitor exhibits an open-circular shape, is based on a flexible printed circuit board with at least two sensing electrodes, optionally a ground electrode, includes a main circuit based on the FPCB, and is free of a casing. The implantation tool exhibits an open-circular shape to reversibly receive the monitor, includes a base to reversibly accommodate the monitor, a handle connected to the base, and a slider reversibly insertable into the base. A process to make the monitor of the kit, the monitor obtainable according to the process, a process to monitor biosignals with the monitor, and the use of the kit, of the monitor and of the implantation tool.

Abstract: A method for connecting a mobile device with a vehicle-based system is described. The vehicle based-system comprises a first device and a second device that are both in possession of a system key. For an initial connection request between the first device and the mobile device, a token pair comprising a plaintext token and an encrypted token has been provided. The encrypted token is obtainable by applying the system key to at least the plaintext token. The mobile device is connected with the vehicle-based system by receiving, for a subsequent connection request with the second device and from the mobile device, the token pair comprising the plaintext token and the encrypted token. The token pair is verified using at least the system key. The subsequent connection is accepted upon successful verification of the token pair.

Abstract: A method for connecting a mobile device with a vehicle-based system is described. The vehicle based-system comprises a first device and a second device that are both in possession of a system key. For an initial connection request between the first device and the mobile device, a token pair comprising a plaintext token and an encrypted token has been provided. The encrypted token is obtainable by applying the system key to at least the plaintext token. The mobile device is connected with the vehicle-based system by receiving, for a subsequent connection request with the second device and from the mobile device, the token pair comprising the plaintext token and the encrypted token. The token pair is verified using at least the system key. The subsequent connection is accepted upon successful verification of the token pair.

Abstract: A method for closing an opening at a target site including bodily tissue including embedding a plurality of self-closing clips into the target site in a spaced apart manner about a perimeter of the opening. Each of the clips has opposing clip ends and an intermediate segment. A flexible tether is coupled to the embedded clips to form a loop about the opening perimeter. A pulling force is applied onto at least one of the loop ends, thereby drawing the perimeter of the opening onto itself to completely close the opening. The loop ends are secured to maintain the target site in a closed state. In some embodiments, the target site is apical cardiac tissue, and the method is performed as part of a trans-apical access procedure.

Abstract: A method for closing an opening at a target site including bodily tissue including embedding a plurality of self-closing clips into the target site in a spaced apart manner about a perimeter of the opening. Each of the clips has opposing clip ends and an intermediate segment. A flexible tether is coupled to the embedded clips to form a loop about the opening perimeter. A pulling force is applied onto at least one of the loop ends, thereby drawing the perimeter of the opening onto itself to completely close the opening. The loop ends are secured to maintain the target site in a closed state. In some embodiments, the target site is apical cardiac tissue, and the method is performed as part of a trans-apical access procedure.

Abstract: This invention relates to a medicament for protecting human mucosal cells from chemotherapy or radiotherapy induced cell death using formulations comprising adenosine or adenosine analogues as a reversible inhibitor of epithelial cell proliferation. The invention also relates to formulations containing adenosine for the prevention of or reduction in mucositis symptoms.

Abstract: Methods for interfering with the growth of fungi by exposing the fungi to an antimicrobial agent derived from cream, and more particularly, to methods for treating human fungal pathogens such as Candida albicans and Aspergillus fumigatus, through exposing the fungi to free fatty acids with antimicrobial activity derived from cream.

Abstract: Compounds of formula (I) or a pharmaceutically or veterinarily acceptable salts thereof wherein R1 represents hydrogen, C1-C6 alkyl or C1-C6 alkyl substituted by one or more halogen atoms; R2 represents a group R10-(ALK)m-, and A represents (i) a group of formula (IA): wherein the compounds inhibit the activity of bacterial PDF enzyme.

Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:

Abstract: The present invention provides a heat exchange system for a closed loop fuel delivery system. The heat exchange system generally includes a first pump, a heat exchanger, a high pressure pump pressurizes fuel. The heat exchanger, which is located downstream of the first pump, receives the pressurized fuel flow. The high pressure pump, which is located downstream of the heat exchanger, delivers a predetermined amount of fuel flow to a jet engine. The circulating pump receives fuel flow downstream of the heat exchanger and recirculates the fuel flow upstream of the heat exchanger.

Abstract: A compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof for the inhibition of activity of bacterial PDF enzyme: wherein A represents a group of formula (IA) or (IB) and wherein R1 is hydrogen, R2 is n-butyl, benzyl or cyclopentylmethyl, R3 is hydrogen, R4 is tert-butyl, iso-butyl, benzyl or methyl, R5 is hydrogen or methyl and R6 is methyl.

Abstract: Vane pump (10) mechanical losses are reduced by removing vane friction losses and replacing them with lower magnitude journal bearing fluid film viscous drag losses. A freely rotating cam ring (70) is supported by a journal bearing (80). A relatively low sliding velocity is imposed between the cam ring and the vanes (26). This permits the use of less expensive and less brittle materials in the pump by allowing the pump to operate at much higher speeds without concern for exceeding vane tip velocity limits.

Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:

Abstract: A bearing assembly is provided for a fuel delivery system that includes a pump (10) having a housing that rotatably receives a rotor (20) carrying vanes (26) thereon, a cam ring (70) received between the housing and rotor (20), and a support member of yoke (50) encompassing the cam ring (70) to selectively vary fuel flow. The bearing assembly (80) is a journal bearing between the yoke (50) and the cam ring (70) and includes an annular surface having a central opening therethrough. The annular surface includes a first, high pressure pad (102) and a second, low pressure pad (104) substantially diametrically opposite the first pad and separated by first and second lands (106, 108). The circumferential extent of the first pad (102) is at least as great as an inner diameter of the cam ring (70). Circumferential ends of the second pad (104) are wider than circumferential ends of the first pad.

Abstract: A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt thereof:

Abstract: Selected compounds of formula (I) are antibacterial agents: formula (I) wherein R2 represents a substituted or unsubstituted C1-C6 alkyl, cycloalkyl (C1-C6 alkyl)- or aryl (C1-C6 alkyl)-group, and A represents a group of formula (IA), or (IB) wherein R4 represents the side chain of a natural or non-natural alpha amino acid, and R5 and R6 are each independently hydrogen or C1-C6 alkyl, heterocyclic or aryl (C1-C6 alkyl)-, R5 and R6 when taken together with the nitrogen atom to which they are attached from an optionally substituted saturated heterocyclic ring of 3 to 8 atoms which ring is optionally fused to a carbocyclic or second heterocyclic ring

Abstract: Compounds of formula (I) are antibacterials: wherein: R1 represents hydrogen, or C1-C6 alkyl or C1-C6 alkyl substituted by one or more halogen atoms; R2 represents a group R10—(X)n—(ALK)m— wherein R10 represents hydrogen, or a C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, cycloalkyl, aryl, or heterocyclyl group, any of which may be unsubstituted or substituted by (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy, mercapto, (C1-C6)alkylthio, amino, halo (including fluoro, chloro, bromo and iodo), trifluoromethyl, cyano, nitro, —COOH, —CONH2, —COORA, —NHCORA, —CONHRA, —NHRA, —NRARB, or —CONRARB wherein RA and RB are independently a (C1-C6)alkyl group, and ALK represents a straight or branched divalent C1-C6 alkylene, C2-C6 alkenylene, or C2-C6 alkynylene radical, and may be interrupted by one or more non-adjacent —NH—, —O— or —S— linkages, X represents —NH—, —O— or —S—, an

Abstract: A dropping tool for transferring drops of a liquid onto a substrate wherein a surface of the dropping tool for contact with the liquid has a first region which exhibits an affinity to the liquid to be transferred directly surrounded by a second region which exhibits a lower affinity to the liquid to be transferred than the first region; the topography of the first and second regions and the relative affinities of the first and second regions for the liquid to be transferred being selected such that when the dropping tool is dipped into and then removed from a source of the liquid to be transferred, the liquid adheres to the first region without substantially any adherence of the liquid to the second region. A dropping tool for transferring drops of liquid onto a substrate, the dropping tool comprising a tip, at least one surface tapered towards the tip, and a capillary channel which leads from a position of the tapered surface remote from the tip to a reservoir located within the dropping tool.