Patents by Inventor Martin Duennwald

Martin Duennwald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treatment of protein misfolding diseases
    Patent number: 8192986
    Abstract: Disclosed are methods for identifying compounds that modulate huntingtin mediated impairment of protein degradation pathways. Compounds identified by such screens can be used as candidate drugs for the treatment of prevention of polyglutamine diseases such as Huntington's Disease.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: June 5, 2012
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Susan L. Lindquist, Martin Duennwald
  • Compositions and Methods for Treatment of Protein Misfolding Diseases
    Publication number: 20080045607
    Abstract: Disclosed are methods for identifying compounds that modulate huntingtinmediated impairment of protein degradation pathways. Compounds identified by such screens can be used as candidate drugs for the treatment of prevention of polyglutamine diseases such as Huntington's Disease.
    Type: Application
    Filed: May 4, 2005
    Publication date: February 21, 2008
    Inventors: Susan Lindquist, Martin Duennwald
  • DAPH analogs and inhibition of protein aggregation
    Publication number: 20060142591
    Abstract: The invention relates to compounds which inhibit aggregation of proteins or peptides, or disaggregate protein aggregates, and thereby antagonize the toxic effects of such aggregates. The invention also relates to methods for using such compounds and methods for discovering compounds that inhibit protein or peptide aggregation.
    Type: Application
    Filed: October 25, 2005
    Publication date: June 29, 2006
    Inventors: Susan Lindquist, James Shorter, Andrew Steele, Martin Duennwald, Vernon Ingram, Stephen Buchwald, Edward Hennessy