Abstract: The present invention relates to binding molecules that comprise T cell receptor (TCR) variable domains and which can bind to a PRAME peptide-HLA complex. In particular, the present invention relates to binding molecules that bind to PYLGQMINL (SEQ ID NO: 1) in complex with HLA-A24. The invention also relates to the use of such molecules for the treatment of malignant diseases.

Abstract: The present invention relates to binding molecules that comprise T cell receptor (TCR) variable domains and which can bind to a PRAME peptide-HLA complex. In particular, the present invention relates to binding molecules that bind to PYLGQMINL (SEQ ID NO: 1) in complex with HLA-A24. The invention also relates to the use of such molecules for the treatment of malignant diseases.

Abstract: The present invention relates to binding molecules that comprise T cell receptor (TCR) variable domains and which can bind to a PRAME peptide-HLA complex. In particular, the present invention relates to binding molecules that bind to PYLGQMINL (SEQ ID NO: 1) in complex with HLA-A24. The invention also relates to the use of such molecules for the treatment of malignant diseases.

Abstract: Proposed is a transport device for transporting a carrier in the form of a foil for producing electrodes for energy accumulators, in particular electrodes for lithium-ion batteries, having at least two rollers on which the carrier is able to be borne, and of which at least one of the rollers is provided with a drive so as to, by rotation of the driven roller, move the carrier along the longitudinal extent thereof, and transport the carrier from roller to roller. Provided for improving the manufacturing quality is a drive device for generating an additional force which facilitates transport and which for generating an alternating magnetic field has an alternating field generator that generates a temporally changing magnetic field so as to induce eddy currents in the carrier, and so as to exert a Lorentz force on the charges flowing in the carrier as a consequence of the eddy currents.

Abstract: Proposed is a transport device for transporting a carrier in the form of a foil for producing electrodes for energy accumulators, in particular electrodes for lithium-ion batteries, having at least two rollers on which the carrier is able to be borne, and of which at least one roller is provided with a drive so as to transport the carrier from roller to roller. Provided for reducing creasing is a drive device for generating an additional force that facilitates transport, wherein the drive device for generating an alternating magnetic field has an alternating field generator which generates a temporally alternating magnetic field, the magnetic field being oriented such that, in addition to the effect of force in the transport direction, an effect of force perpendicular to the transport direction is initiated in the plane of the carrier.

Abstract: The invention relates to a method for producing a substrate coated with a paste or dry coating, the method comprising: providing a film; providing a paste/dry coating; coating the film with the paste in order to obtain a coated substrate; and drying the paste or solidifying the dry coating on the substrate, the substrate being transported in a transport direction between its provision and the drying and/or solidification process, and the particles in the force field being oriented perpendicular to the transport direction. In order to improve the transport process, the substrate is shaped before and/or during the drying/solidification process in order to counteract tensioning of the substrate caused by shrinkage of the coating.

Abstract: A coating device for coating a carrier with a coating is proposed, comprising a transport device for transporting the carrier during the coating process for coating the carrier on at least one side of the carrier and for transportation at least after the application of the paste to one side, and an aligning device. For particularly stable sheet guidance, the transport device comprises a supporting device for the positionally stable supporting of the carrier with regard to the direction perpendicular to the transport surface, in which the carrier lies during transport, and/or perpendicular to the transport direction, which is configured to form a mechanical constraint for the range of movement of the carrier perpendicular to the surface in the direction of the uncoated side of the carrier, in order to counteract a change in the position with regard to the direction perpendicular to the surface.

Abstract: A self-propelled sweeping machine has a sweepings pick-up device and a sweepings collection container. The pick-up device has a pick-up head and a conveying section adjoining the head having an ejection and distribution device opening into an interior of the collection container. Sweepings picked up from the traffic surface by the pick-up device can be distributed by the ejection and distribution device, with the formation of a sweepings surface, in the interior of the collection container. Also provided is a filling level sensor, which is configured as a radar sensor and scans the interior of the sweepings collection container, and an evaluation unit which interacts with the filling level sensor. A distance measured between the filling level sensor and the sweepings surface allows for the degree of filling of the sweepings collection container to be determined in the evaluation unit and to be output on a display or signal unit.

Abstract: A method of dry coating of surfaces of a carrier and/or of production of self-standing layers, especially for use in lithium ion batteries having improved properties, is proposed, wherein the coating is effected at least by means of a particle-comprising powder in the dry state, especially having a solvent content of less than 1% by weight, and alignment of the particles is conducted in order to reduce the ionic resistance of the powder layer. The alignment of the particles additionally comprises fluidization of the powder.

Abstract: What is proposed is a method for accurately determining an electric current (Iin, Iin,0) with reduced technical outlay, comprising: connecting a circuit branch (2, 12) in parallel with an inaccurate but current-loadable shunt resistor (Rsh), wherein a reference resistor (Rref) that is more accurate in comparison with the shunt resistor (Rsh) but less current-loadable is connected into the circuit branch (2, 12), such that the circuit branch (2, 12) branches off in each case at a node point (K) upstream and downstream of the shunt resistor, generating a temporally changeable reference current (Iref, I?ref, I?ref) through the circuit branch (2, 12), measuring the voltages (V?sh, V?sh, V?ref, V?ref) across the shunt resistor (Rsh) and across the reference resistor (Rref), determining the current strength (Iin, Iin,0) upstream and downstream of the node point (K).

Abstract: The invention relates to a method for orienting particles in a paste, comprising: providing the paste, which comprises particles that can be oriented in the paste, wherein the paste comprises, in particular, carbon-based particles, preferably graphite, and/or a volatile substance, and exposing the paste to the influence of a force field such that the particles experience a force due to the interaction with the force field, by means of which the particles are oriented relative to the field lines of the force field. For cost savings and improvement to productivity, the paste is heated in order to at least temporarily reduce the viscosity of the paste and to reduce the orientation time required for orienting the particles in the force field, wherein the paste is heated before exposing and/or while exposing the paste to the influence of the force field.

Abstract: The present invention relates to a pharmaceutical formulation comprising (i) a therapeutically effective amount of a bispecific protein comprising a soluble T cell receptor (TCR) and an scFV; and (ii) a surfactant. The w/w ratio of surfactant to protein is in the range of 0.75:1 to 1.5:1. The formulation may further comprise a bulking agent and/or a stabiliser. A further pharmaceutical formulation comprises (i) a therapeutically effective amount of a bispecific protein comprising a soluble T cell receptor (TCR) and an scFV; (ii) a bulking agent; and (iii) a stabiliser. The w/w ratio of stabiliser to bulking agent may be greater than 1:1.

Abstract: Processes for applying magnetic fields to articles such as a layer or layer-coated articles, and more particularly to coatings having graphite particles, preferably for manufacture of negative electrodes having aligned graphite particles, for example for fast-charging lithium-ion batteries. The application of magnetic fields may be continuous. For this, magnetic tools with permanent magnets may be used for applying magnetic fields, wherein an article is moved relative to a magnetic tool. Application of magnetic field is made before the initiation of a drying phase and/or during a drying phase.

Abstract: A side skirt arrangement of a body of an electrically operable motor vehicle includes a side skirt which has a hollow profile at least in a longitudinal region and to which a battery support frame is attachable by a first fixing element at a fixing point of the side skirt. The side skirt arrangement also includes a reinforcing element disposed within a cavity of the side skirt, where the reinforcing element extends in a transverse direction of the electrically operable vehicle at least over approximately an entire width of the side skirt between two walls of the side skirt. The reinforcing element is disposed in a region of the fixing point and is disposed in a transverse direction of the electrically operable motor vehicle at least partially overlapping with an attached battery support frame.

Abstract: The invention relates to a motor vehicle headlight (100), comprising a headlight housing (102) and a cover plate (103) having at least one light source (104, 105) arranged in said motor vehicle headlight (100). In order to cool the at least one light source (104, 105), a heat sink device (200) is provided. Said heat sink device (200) comprises two heat sink elements (106, 107, 201, 202, 501, 502, 601, 602, 701, 702, 801, 802, 901, 902, 1001, 1002) that are separated from one another by an air gap (209) and that are arranged in such a way that a first heat sink element (106, 201, 501, 601, 701, 801, 901, 1001) is mounted inside the motor vehicle headlight (100), and a second heat sink element (107, 202, 502, 602, 702, 802, 902, 1002) is mounted outside the motor vehicle headlight (100).

Abstract: The invention relates to a motor vehicle headlight (100), comprising a headlight housing (102) and a cover plate (103) having at least one light source (104, 105) arranged in said motor vehicle headlight (100). In order to cool the at least one light source (104, 105), a heat sink device (200) is provided. Said heat sink device (200) comprises two heat sink elements (106, 107, 201, 202, 501, 502, 601, 602, 701, 702, 801, 802, 901, 902, 1001, 1002) that are separated from one another by an air gap (209) and that are arranged in such a way that a first heat sink element (106, 201, 501, 601, 701, 801, 901, 1001) is mounted inside the motor vehicle headlight (100), and a second heat sink element (107, 202, 502, 602, 702, 802, 902, 1002) is mounted outside the motor vehicle headlight (100).

Abstract: The present invention relates to novel hardeners for curing epoxy resins and to cure accelerants for the accelerated curing of epoxy resins comprising, in each case, at least one compound from the group of esters of phosphorus-containing acids according to Formula (I), wherein there applies to Formula (I): wherein there applies to the radicals R1, R2, R3, R6, X and indices m, n, p, simultaneously or independently of one another: R1, R2=simultaneously or independently of one another, hydrogen or alkyl, R3=alkyl, aryl, —O-alkyl, —O-aryl, —O-alkylaryl or —O-arylalkyl, R6=hydrogen, alkyl or —NHC(O)NR1R2, X=oxygen or sulphur, m=1, 2 or 3, n=0, 1 or 2, wherein there applies: m+n=3 p=0, 1 or 2.

Abstract: The invention relates to a method for applying magnetic fields to an article (020), which is in particular a layer or a layer-coated article, and more particularly to a coating having graphite particles, preferably for manufacture of a negative electrode with aligned graphite particles, for example for fast-charging lithium-ion batteries. In particular, the application of magnetic fields should be continuous. For this, a magnetic tool with permanent magnets (010) is used for applying magnetic fields, wherein the article is moved relative to the magnetic tool. The application of the magnetic field is carried out in particular before the initiation of a drying phase (030) and/or during the drying phase.